Helicase_C

• Pfam ID: Helicase_C
• Description: Helicase conserved C-terminal domain
• Accession: PF00271
• Interpro ID: IPR001650
• GO ID:

  GO:0003676

  GO:0004386

  GO:0005524

Helicase_C forms interactions with

Pfam ID	Description	Accession	Interpro ID	GO ID	Notes	Source
SNF2_N	SNF2 family N-terminal domain	PF00176	IPR000330	GO:0003677 GO:0005524
DEAD	DEAD/DEAH box helicase	PF00270	IPR011545	GO:0003676 GO:0005524 GO:0008026
Helicase_C	Helicase conserved C-terminal domain	PF00271	IPR001650	GO:0003676 GO:0004386 GO:0005524
SecA_PP_bind	SecA preprotein cross-linking domain	PF01043	IPR011130	GO:0005515 GO:0016020 GO:0017038
Mago_nashi	Mago nashi protein	PF02792	IPR004023	GO:0005634
MA3	MA3 domain	PF02847	IPR003891
MIF4G	MIF4G domain	PF02854	IPR003890	GO:0005515 GO:0016070
ResIII	Type III restriction enzyme, res subunit	PF04851	IPR006935	GO:0003677 GO:0005524 GO:0016787
SecA_SW	SecA Wing and Scaffold domain	PF07516	IPR011116	GO:0016020 GO:0017038
SecA_DEAD	SecA DEAD-like domain	PF07517	IPR011115	GO:0005524 GO:0016020 GO:0017038
Flavi_DEAD	Flavivirus DEAD domain	PF07652	IPR011492	GO:0005524 GO:0008026 GO:0019079
DUF1605	Domain of unknown function (DUF1605)	PF07717	IPR011709
DSHCT	DSHCT (NUC185) domain	PF08148	IPR012961	GO:0005524 GO:0016818
RQC	RQC domain	PF09382	IPR018982	GO:0006260 GO:0006281 GO:0043140
Btz	CASC3/Barentsz eIF4AIII binding	PF09405	IPR018545
dsrm	Double-stranded RNA binding motif	PF00035	IPR001159	GO:0003725 GO:0005622
Pkinase	Protein kinase domain	PF00069	IPR017442	GO:0004672 GO:0005524 GO:0006468
RRM_1	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	PF00076	IPR000504	GO:0003676
zf-C3HC4	Zinc finger, C3HC4 type (RING finger)	PF00097	IPR018957
Myb_DNA-binding	Myb-like DNA-binding domain	PF00249	IPR014778
2-Hacid_dh	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	PF00389	IPR006139	GO:0008152 GO:0016616 GO:0051287
Bromodomain	Bromodomain	PF00439	IPR001487
RdRP_1	RNA dependent RNA polymerase	PF00680	IPR001205	GO:0003723 GO:0003968 GO:0006350
Peptidase_C4	Peptidase family C4	PF00863	IPR001730	GO:0006508 GO:0008234
Flavi_glycoprot	Flavivirus glycoprotein, central and dimerisation domains	PF00869	IPR011999	GO:0016021 GO:0019031
Peptidase_S7	Peptidase S7, Flavivirus NS3 serine protease	PF00949	IPR001850	GO:0003723 GO:0003724 GO:0005524
Flavi_NS5	Flavivirus RNA-directed RNA polymerase	PF00972	IPR000208	GO:0003968 GO:0005524
RdRP_3	Viral RNA dependent RNA polymerase	PF00998	IPR002166	GO:0003723 GO:0003968 GO:0005524 GO:0006350 GO:0019079
HCV_NS4a	Hepatitis C virus non-structural protein NS4a	PF01006	IPR000745	GO:0016032 GO:0044423
tRNA_anti	OB-fold nucleic acid binding domain	PF01336	IPR004365	GO:0003676
LSM	LSM domain	PF01423	IPR001163
FtsJ	FtsJ-like methyltransferase	PF01728	IPR002877	GO:0003676 GO:0008168 GO:0032259
UVR	UvrB/uvrC motif	PF02151	IPR001943	GO:0003677 GO:0004518 GO:0006289
Flavi_glycop_C	Flavivirus glycoprotein, immunoglobulin-like domain	PF02832	IPR000336	GO:0005198 GO:0019031
Peptidase_S29	Hepatitis C virus NS3 protease	PF02907	IPR004109	GO:0006508 GO:0008236 GO:0019087
Brix	Brix domain	PF04427	IPR007109
zf-CCHC	Zinc knuckle	PF00098	IPR001878	GO:0003676 GO:0008270
adh_short	short chain dehydrogenase	PF00106	IPR002198	GO:0008152 GO:0016491
Histone	Core histone H2A/H2B/H3/H4	PF00125	IPR007125	GO:0003677
UQ_con	Ubiquitin-conjugating enzyme	PF00179	IPR000608	GO:0019787 GO:0043687 GO:0051246
Aminotran_3	Aminotransferase class-III	PF00202	IPR005814	GO:0008483 GO:0030170
Ribonuc_red_sm	Ribonucleotide reductase, small chain	PF00268	IPR000358	GO:0004748 GO:0009186 GO:0055114
CPSase_L_chain	Carbamoyl-phosphate synthase L chain, N-terminal domain	PF00289	IPR005481	GO:0003824 GO:0008152
Ribosomal_L3	Ribosomal protein L3	PF00297	IPR000597	GO:0003735 GO:0005622 GO:0005840 GO:0006412
Aconitase	Aconitase family (aconitate hydratase)	PF00330	IPR001030	GO:0008152
polyprenyl_synt	Polyprenyl synthetase	PF00348	IPR000092	GO:0008299
Dynamin_N	Dynamin family	PF00350	IPR001401	GO:0003924 GO:0005525
WD40	WD domain, G-beta repeat	PF00400	IPR019781
MutS_V	MutS domain V	PF00488	IPR000432	GO:0005524 GO:0006298 GO:0030983
FHA	FHA domain	PF00498	IPR000253
HMG_box	HMG (high mobility group) box	PF00505	IPR000910	GO:0003677 GO:0005634
BRCT	BRCA1 C Terminus (BRCT) domain	PF00533	IPR001357	GO:0005622
RNA_pol_Rpb2_6	RNA polymerase Rpb2, domain 6	PF00562	IPR007120	GO:0003677 GO:0003899 GO:0006350
S1	S1 RNA binding domain	PF00575	IPR003029	GO:0003723
PHD	PHD-finger	PF00628	IPR019787
E1_dh	Dehydrogenase E1 component	PF00676	IPR001017	GO:0008152 GO:0016624
Aconitase_C	Aconitase C-terminal domain	PF00694	IPR000573	GO:0008152
HhH-GPD	HhH-GPD superfamily base excision DNA repair protein	PF00730	IPR003265	GO:0006284
XPG_N	XPG N-terminal domain	PF00752	IPR006085	GO:0004518 GO:0006281
PUF	Pumilio-family RNA binding repeat	PF00806	IPR001313	GO:0003723
XPG_I	XPG I-region	PF00867	IPR006086	GO:0004518 GO:0006281
GTP1_OBG	GTP1/OBG	PF01018	IPR006169	GO:0005525
Dynamin_M	Dynamin central region	PF01031	IPR000375	GO:0005525
RNase_PH	3' exoribonuclease family, domain 1	PF01138	IPR001247	GO:0000175 GO:0003723 GO:0006396
Nol1_Nop2_Fmu	NOL1/NOP2/sun family	PF01189	IPR001678
MutS_I	MutS domain I	PF01624	IPR007695	GO:0005524 GO:0006298 GO:0030983
IF4E	Eukaryotic initiation factor 4E	PF01652	IPR001040	GO:0003723 GO:0003743 GO:0005737 GO:0006413
NTP_transf_2	Nucleotidyltransferase domain	PF01909	IPR002934	GO:0016779
eIF-6	eIF-6 family	PF01912	IPR002769	GO:0042256 GO:0043022
HAT	HAT (Half-A-TPR) repeat	PF02184	IPR003107	GO:0005622 GO:0006396
GED	Dynamin GTPase effector domain	PF02212	IPR003130	GO:0003924 GO:0005525
ERCC4	ERCC4 domain	PF02732	IPR006166	GO:0003677 GO:0004518 GO:0005515 GO:0006259
CPSase_L_D2	Carbamoyl-phosphate synthase L chain, ATP binding domain	PF02786	IPR005479	GO:0003824 GO:0005524 GO:0008152
TGS	TGS domain	PF02824	IPR004095
2-Hacid_dh_C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	PF02826	IPR006140	GO:0016616 GO:0048037
AAA	ATPase family associated with various cellular activities (AAA)	PF00004	IPR003959	GO:0005524
ABC_tran	ABC transporter	PF00005	IPR003439	GO:0005524 GO:0016887
GTP_EFTU	Elongation factor Tu GTP binding domain	PF00009	IPR000795	GO:0003924 GO:0005525
SH3_1	SH3 domain	PF00018	IPR001452
efhand	EF hand	PF00036	IPR018248
GST_C	Glutathione S-transferase, C-terminal domain	PF00043	IPR004046
Homeobox	Homeobox domain	PF00046	IPR001356	GO:0003700 GO:0006355 GO:0043565
Ldh_1_N	lactate/malate dehydrogenase, NAD binding domain	PF00056	IPR001236	GO:0016491 GO:0055114
Ras	Ras family	PF00071	IPR013753
zf-C2H2	Zinc finger, C2H2 type	PF00096	IPR007087	GO:0005622 GO:0008270
ADH_zinc_N	Zinc-binding dehydrogenase	PF00107	IPR013149	GO:0008270 GO:0016491 GO:0055114
Metallophos	Calcineurin-like phosphoesterase	PF00149	IPR004843	GO:0016787
Mito_carr	Mitochondrial carrier protein	PF00153	IPR018108
Pro_isomerase	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	PF00160	IPR002130	GO:0003755 GO:0006457
Ribosomal_L2	Ribosomal Proteins L2, RNA binding domain	PF00181	IPR022666	GO:0003735 GO:0005622 GO:0005840 GO:0006412
DNA_gyraseB	DNA gyrase B	PF00204	IPR013506	GO:0003677 GO:0003918 GO:0005524 GO:0005694 GO:0006265
TPP_enzyme_M	Thiamine pyrophosphate enzyme, central domain	PF00205	IPR012000	GO:0000287 GO:0030976
DnaJ	DnaJ domain	PF00226	IPR001623	GO:0031072
Proteasome	Proteasome A-type and B-type	PF00227	IPR001353	GO:0004298 GO:0005839 GO:0051603
ubiquitin	Ubiquitin family	PF00240	IPR000626
Fork_head	Fork head domain	PF00250	IPR001766	GO:0003700 GO:0005634 GO:0006355 GO:0043565
Ribosomal_L16	Ribosomal protein L16p/L10e	PF00252	IPR016180	GO:0003735 GO:0005840 GO:0006412
Ribosomal_L30	Ribosomal protein L30p/L7e	PF00327	IPR000517	GO:0003735 GO:0005840 GO:0006412
Acid_phosphat_A	Histidine acid phosphatase	PF00328	IPR000560	GO:0003993
PFK	Phosphofructokinase	PF00365	IPR000023	GO:0003872 GO:0005945 GO:0006096
Ribosomal_S9	Ribosomal protein S9/S16	PF00380	IPR000754	GO:0003735 GO:0005622 GO:0005840 GO:0006412
Chromo	'chromo' (CHRromatin Organisation MOdifier) domain	PF00385	IPR000953	GO:0000785 GO:0003682 GO:0005634 GO:0006333
WW	WW domain	PF00397	IPR001202	GO:0005515
Pkinase_C	Protein kinase C terminal domain	PF00433	IPR017892	GO:0004674 GO:0005524 GO:0006468
UCH	Ubiquitin carboxyl-terminal hydrolase	PF00443	IPR001394	GO:0004221 GO:0006511
PI3_PI4_kinase	Phosphatidylinositol 3- and 4-kinase	PF00454	IPR000403	GO:0016773
PP2C	Protein phosphatase 2C	PF00481	IPR014045
AMP-binding	AMP-binding enzyme	PF00501	IPR000873	GO:0003824 GO:0008152
Arm	Armadillo/beta-catenin-like repeat	PF00514	IPR000225
TPR_1	Tetratricopeptide repeat	PF00515	IPR001440
ZZ	Zinc finger, ZZ type	PF00569	IPR000433	GO:0008270
HRDC	HRDC domain	PF00570	IPR002121	GO:0003676 GO:0005622
SPRY	SPRY domain	PF00622	IPR003877
RNA_pol_Rpb1_2	RNA polymerase Rpb1, domain 2	PF00623	IPR000722	GO:0003677 GO:0003899 GO:0006350
UBA	UBA/TS-N domain	PF00627	IPR000449
HECT	HECT-domain (ubiquitin-transferase)	PF00632	IPR000569	GO:0005622 GO:0006464 GO:0016881
HHH	Helix-hairpin-helix motif	PF00633	IPR000445	GO:0003677
Ribonuclease_3	RNase3 domain	PF00636	IPR000999	GO:0003723 GO:0004525 GO:0006396
PARP	Poly(ADP-ribose) polymerase catalytic domain	PF00644	IPR012317	GO:0003950
F-box	F-box domain	PF00646	IPR001810
Peptidase_M16	Insulinase (Peptidase family M16)	PF00675	IPR011765	GO:0004222 GO:0006508
Hydrolase	haloacid dehalogenase-like hydrolase	PF00702	IPR005834	GO:0003824 GO:0008152
Pyrophosphatase	Inorganic pyrophosphatase	PF00719	IPR008162	GO:0000287 GO:0004427 GO:0005737 GO:0006796
Oxidored_FMN	NADH:flavin oxidoreductase / NADH oxidase family	PF00724	IPR001155	GO:0010181 GO:0016491
THF_DHG_CYH	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	PF00763	IPR020630	GO:0003824 GO:0009396
Glyco_transf_20	Glycosyltransferase family 20	PF00982	IPR001830	GO:0003824 GO:0005992
RNA_pol_A_bac	RNA polymerase Rpb3/RpoA insert domain	PF01000	IPR011262	GO:0003899 GO:0006350 GO:0046983
DNA_ligase_A_M	ATP dependent DNA ligase domain	PF01068	IPR012310	GO:0003910 GO:0005524 GO:0006260 GO:0006281 GO:0006310
EMP24_GP25L	emp24/gp25L/p24 family/GOLD	PF01105	IPR000348	GO:0006810 GO:0016021
CK_II_beta	Casein kinase II regulatory subunit	PF01214	IPR000704	GO:0005956 GO:0019887
Ribosomal_L7Ae	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	PF01248	IPR004038
FTHFS	Formate--tetrahydrofolate ligase	PF01268	IPR000559	GO:0004329 GO:0005524 GO:0009396
Fibrillarin	Fibrillarin	PF01269	IPR000692	GO:0003723 GO:0006364 GO:0008033 GO:0008168
mRNA_cap_enzyme	mRNA capping enzyme, catalytic domain	PF01331	IPR001339	GO:0004484 GO:0006370 GO:0006397
Mov34	Mov34/MPN/PAD-1 family	PF01398	IPR000555
PUA	PUA domain	PF01472	IPR002478	GO:0003723
TruB_N	TruB family pseudouridylate synthase (N terminal domain)	PF01509	IPR002501	GO:0006396
G-patch	G-patch domain	PF01585	IPR000467	GO:0003676 GO:0005622
Adaptin_N	Adaptin N terminal region	PF01602	IPR002553	GO:0005515 GO:0006886 GO:0016192 GO:0030117
3_5_exonuc	3'-5' exonuclease	PF01612	IPR002562	GO:0003676 GO:0005622 GO:0006139 GO:0008408
TIG	IPT/TIG domain	PF01833	IPR002909
ACT	ACT domain	PF01842	IPR002912	GO:0008152 GO:0016597
MMR_HSR1	GTPase of unknown function	PF01926	IPR002917	GO:0005525 GO:0005622
zf-CXXC	CXXC zinc finger domain	PF02008	IPR002857	GO:0003677 GO:0008270
MGS	MGS-like domain	PF02142	IPR011607
AT_hook	AT hook motif	PF02178	IPR017956	GO:0003677
FH2	Formin Homology 2 Domain	PF02181	IPR015425
RFX_DNA_binding	RFX DNA-binding domain	PF02257	IPR003150	GO:0003677 GO:0006355
FAT	FAT domain	PF02259	IPR003151
FATC	FATC domain	PF02260	IPR003152
E2F_TDP	E2F/DP family winged-helix DNA-binding domain	PF02319	IPR003316	GO:0003700 GO:0005667 GO:0006355
HATPase_c	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	PF02518	IPR003594	GO:0005524
TPP_enzyme_C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	PF02775	IPR011766	GO:0003824 GO:0030976
TPP_enzyme_N	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	PF02776	IPR012001	GO:0030976
Transket_pyr	Transketolase, pyrimidine binding domain	PF02779	IPR005475
CPSase_L_D3	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	PF02787	IPR005480	GO:0004086 GO:0006807
GST_N	Glutathione S-transferase, N-terminal domain	PF02798	IPR004045
SEC-C	SEC-C motif	PF02810	IPR004027
Ldh_1_C	lactate/malate dehydrogenase, alpha/beta C-terminal domain	PF02866	IPR022383
PARP_reg	Poly(ADP-ribose) polymerase, regulatory domain	PF02877	IPR004102	GO:0003950 GO:0006471
THF_DHG_CYH_C	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain	PF02882	IPR020631	GO:0003824 GO:0009396
Sec63	Sec63 Brl domain	PF02889	IPR004179
HEAT	HEAT repeat	PF02985	IPR000357
4HBT	Thioesterase superfamily	PF03061	IPR006683
RNase_PH_C	3' exoribonuclease family, domain 2	PF03725	IPR015847	GO:0000175 GO:0003723 GO:0006396
SecG	Preprotein translocase SecG subunit	PF03840	IPR004692	GO:0009306 GO:0015450 GO:0016021
DbpA	DbpA RNA binding domain	PF03880	IPR005580
CBF	CBF/Mak21 family	PF03914	IPR005612
Ribosomal_L2_C	Ribosomal Proteins L2, C-terminal domain	PF03947	IPR022669	GO:0003735 GO:0005622 GO:0005840 GO:0006412
PWP2	Periodic tryptophan protein 2 WD repeat associated presumed domain	PF04047
HSDR_N	Type I restriction enzyme R protein N terminus (HSDR_N)	PF04313	IPR007409	GO:0003677 GO:0004519 GO:0006304
HA2	Helicase associated domain (HA2)	PF04408	IPR007502	GO:0004386
SWIM	SWIM zinc finger	PF04434	IPR007527	GO:0008270
RNA_pol_Rpb2_7	RNA polymerase Rpb2, domain 7	PF04560	IPR007641	GO:0003677 GO:0003899 GO:0006350
RNA_pol_Rpb2_2	RNA polymerase Rpb2, domain 2	PF04561	IPR007642	GO:0003677 GO:0003899 GO:0006350
RNA_pol_Rpb2_1	RNA polymerase beta subunit	PF04563	IPR007644	GO:0003677 GO:0003899 GO:0006350
RNA_pol_Rpb2_3	RNA polymerase Rpb2, domain 3	PF04565	IPR007645	GO:0003677 GO:0003899 GO:0006350
RNA_pol_Rpb1_3	RNA polymerase Rpb1, domain 3	PF04983	IPR007066	GO:0003677 GO:0003899 GO:0006350
RNA_pol_Rpb1_1	RNA polymerase Rpb1, domain 1	PF04997	IPR007080	GO:0003677 GO:0003899 GO:0006350
RNA_pol_Rpb1_5	RNA polymerase Rpb1, domain 5	PF04998	IPR007081	GO:0003677 GO:0003899 GO:0006350
RNA_pol_Rpb1_4	RNA polymerase Rpb1, domain 4	PF05000	IPR007083	GO:0003677 GO:0003899 GO:0006350
RCSD	RCSD region	PF05177	IPR007850
MutS_II	MutS domain II	PF05188	IPR007860	GO:0005524 GO:0006298 GO:0030983
MutS_IV	MutS family domain IV	PF05190	IPR007861	GO:0005524 GO:0006298 GO:0030983
MutS_III	MutS domain III	PF05192	IPR007696	GO:0005524 GO:0006298 GO:0030983
CHL4	Kinetochore protein CHL4 like	PF05238	IPR007902
KRE9	Yeast cell wall synthesis protein KRE9/KNH1	PF05390	IPR008659	GO:0005576 GO:0042546
DEAD_2	DEAD_2	PF06733	IPR010614	GO:0003677 GO:0004003 GO:0005524
DUF1227	Protein of unknown function (DUF1227)	PF06777	IPR010643	GO:0004003 GO:0005634 GO:0006289 GO:0016818
EIF_2_alpha	Eukaryotic translation initiation factor 2 alpha subunit	PF07541	IPR011488	GO:0003723 GO:0003743 GO:0005850 GO:0006412
EGF_CA	Calcium binding EGF domain	PF07645	IPR013091
DUF1753	Golgi protein of unknown function (DUF1753)	PF08552	IPR013862