Ras

• Pfam ID: Ras
• Description: Ras family
• Accession: PF00071
• Interpro ID: IPR013753

Ras forms interactions with

Pfam ID	Description	Accession	Interpro ID	GO ID	Notes	Source
Pkinase	Protein kinase domain	PF00069	IPR017442	GO:0004672 GO:0005524 GO:0006468
Ras	Ras family	PF00071	IPR013753
PH	PH domain	PF00169	IPR001849
RCC1	Regulator of chromosome condensation (RCC1)	PF00415	IPR000408
PI3_PI4_kinase	Phosphatidylinositol 3- and 4-kinase	PF00454	IPR000403	GO:0016773
TPR_1	Tetratricopeptide repeat	PF00515	IPR001440
LRR_1	Leucine Rich Repeat	PF00560	IPR001611	GO:0005515
TBC	TBC domain	PF00566	IPR000195	GO:0005097 GO:0005622 GO:0032313
PDZ	PDZ domain (Also known as DHR or GLGF)	PF00595	IPR001478	GO:0005515
RasGAP	GTPase-activator protein for Ras-like GTPase	PF00616	IPR001936	GO:0005096 GO:0005622 GO:0051056
RasGEF	RasGEF domain	PF00617	IPR001895	GO:0005085 GO:0005622 GO:0007264
RasGEF_N	Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif	PF00618	IPR000651	GO:0005085 GO:0005622 GO:0051056
RhoGAP	RhoGAP domain	PF00620	IPR000198	GO:0005622 GO:0007165
RhoGEF	RhoGEF domain	PF00621	IPR000219	GO:0005089 GO:0005622 GO:0035023
Ran_BP1	RanBP1 domain	PF00638	IPR000156	GO:0046907
zf-RanBP	Zn-finger in Ran binding protein and others	PF00641	IPR001876	GO:0005622 GO:0008270
PBD	P21-Rho-binding domain	PF00786	IPR000095
RA	Ras association (RalGDS/AF-6) domain	PF00788	IPR000159	GO:0007165
PI3K_rbd	PI3-kinase family, ras-binding domain	PF00794	IPR000341	GO:0005942 GO:0016303
PAS	PAS fold	PF00989	IPR013767	GO:0006355
GDI	GDP dissociation inhibitor	PF00996	IPR018203
TIG	IPT/TIG domain	PF01833	IPR002909
Rho_GDI	RHO protein GDP dissociation inhibitor	PF02115	IPR000406	GO:0005094 GO:0005737
NTF2	Nuclear transport factor 2 (NTF2) domain	PF02136	IPR002075	GO:0005622 GO:0006810
Rap_GAP	Rap/ran-GAP	PF02145	IPR000331	GO:0005096 GO:0005622 GO:0051056
HR1	Hr1 repeat	PF02185	IPR000861	GO:0005622 GO:0007165
RBD	Raf-like Ras-binding domain	PF02196	IPR003116	GO:0005057 GO:0007165
VPS9	Vacuolar sorting protein 9 (VPS9) domain	PF02204	IPR003123
RPH3A_effector	Rabphilin-3A effector domain	PF02318	IPR003315	GO:0005515 GO:0006886 GO:0008270 GO:0017137
Fic	Fic/DOC family	PF02661	IPR003812
RUN	RUN domain	PF02759	IPR004012
HEAT	HEAT repeat	PF02985	IPR000357
IpaB_EvcA	IpaB/EvcA family	PF03278	IPR004959	GO:0009405
CAS_CSE1	CAS/CSE protein, C-terminus	PF03378	IPR005043	GO:0005634 GO:0005737 GO:0008262 GO:0008283
Binary_toxA	Clostridial binary toxin A	PF03496	IPR003540	GO:0005576 GO:0009405
YopE	Yersinia virulence determinant (YopE)	PF03545	IPR014773
PRONE	PRONE (Plant-specific Rop nucleotide exchanger)	PF03759	IPR005512	GO:0005089
IBN_N	Importin-beta N-terminal domain	PF03810	IPR001494	GO:0006886 GO:0008565
Sybindin	Sybindin-like family	PF04099	IPR007233	GO:0005801 GO:0006888
Mss4	Mss4 protein	PF04421	IPR007515	GO:0005085 GO:0007264
Drf_FH3	Diaphanous FH3 Domain	PF06367	IPR010472	GO:0003779 GO:0016043
Drf_GBD	Diaphanous GTPase-binding Domain	PF06371	IPR010473	GO:0003779 GO:0017048 GO:0030036
Sec2p	GDP/GTP exchange factor Sec2p	PF06428	IPR009449
Arfaptin	Arfaptin-like domain	PF06456	IPR010504
Ded_cyto	Dedicator of cytokinesis	PF06920	IPR010703	GO:0005085 GO:0005525 GO:0051020
SopE_GEF	SopE GEF domain	PF07487	IPR016019	GO:0005085 GO:0005576 GO:0009405 GO:0031532 GO:0032862
V-set	Immunoglobulin V-set domain	PF07686	IPR013106
Plexin_cytopl	Plexin cytoplasmic region	PF08337	IPR013548
Xpo1	Exportin 1-like protein	PF08389	IPR013598
Cse1	Cse1	PF08506	IPR013713	GO:0006886
CRM1_C	CRM1 C terminal	PF08767	IPR014877
Rho_Binding	Rho Binding	PF08912	IPR015008	GO:0000910 GO:0004674 GO:0005515 GO:0005524 GO:0006468
GTPase_binding	GTPase binding	PF09027	IPR015116
Rab5-bind	Rab5 binding	PF09311	IPR015390
RBD-FIP	FIP domain	PF09457	IPR019018	GO:0015031 GO:0043231
Rac1	Rac1-binding domain	PF09632	IPR019093
SH3_1	SH3 domain	PF00018	IPR001452
Ank	Ankyrin repeat	PF00023	IPR002110
efhand	EF hand	PF00036	IPR018248
ADH_zinc_N	Zinc-binding dehydrogenase	PF00107	IPR013149	GO:0008270 GO:0016491 GO:0055114
PB1	PB1 domain	PF00564	IPR000270
PX	PX domain	PF00787	IPR001683	GO:0005515 GO:0007154 GO:0035091
FYVE	FYVE zinc finger	PF01363	IPR000306
ArfGap	Putative GTPase activating protein for Arf	PF01412	IPR001164	GO:0008060 GO:0008270 GO:0032312
Yip1	Yip1 domain	PF04893	IPR006977	GO:0016020
HLH	Helix-loop-helix DNA-binding domain	PF00010	IPR001092	GO:0030528 GO:0045449
KH_1	KH domain	PF00013	IPR018111	GO:0003723
Arf	ADP-ribosylation factor family	PF00025	IPR006689	GO:0005525
Pyr_redox	Pyridine nucleotide-disulphide oxidoreductase	PF00070	IPR001327	GO:0016491 GO:0050660 GO:0055114
Response_reg	Response regulator receiver domain	PF00072	IPR001789	GO:0000156 GO:0000160 GO:0006355
Hexapep	Bacterial transferase hexapeptide (three repeats)	PF00132	IPR001451
Aminotran_3	Aminotransferase class-III	PF00202	IPR005814	GO:0008483 GO:0030170
TPP_enzyme_M	Thiamine pyrophosphate enzyme, central domain	PF00205	IPR012000	GO:0000287 GO:0030976
Lyase_1	Lyase	PF00206	IPR022761
Cofilin_ADF	Cofilin/tropomyosin-type actin-binding protein	PF00241	IPR002108	GO:0003779 GO:0005622
TFIIB	Transcription factor TFIIB repeat	PF00382	IPR013150	GO:0003743 GO:0005515 GO:0006413
dCMP_cyt_deam_1	Cytidine and deoxycytidylate deaminase zinc-binding region	PF00383	IPR002125	GO:0008270 GO:0016787
Pkinase_C	Protein kinase C terminal domain	PF00433	IPR017892	GO:0004674 GO:0005524 GO:0006468
HSF_DNA-bind	HSF-type DNA-binding	PF00447	IPR000232	GO:0003700 GO:0005634 GO:0006355 GO:0043565
Arginase	Arginase family	PF00491	IPR006035	GO:0016813 GO:0046872
AMP-binding	AMP-binding enzyme	PF00501	IPR000873	GO:0003824 GO:0008152
Arm	Armadillo/beta-catenin-like repeat	PF00514	IPR000225
AA_kinase	Amino acid kinase family	PF00696	IPR001048	GO:0008652
PUF	Pumilio-family RNA binding repeat	PF00806	IPR001313	GO:0003723
Glyco_transf_20	Glycosyltransferase family 20	PF00982	IPR001830	GO:0003824 GO:0005992
GrpE	GrpE	PF01025	IPR000740	GO:0000774 GO:0005739 GO:0006457 GO:0030150 GO:0042803 GO:0051087
F_actin_cap_B	F-actin capping protein, beta subunit	PF01115	IPR001698	GO:0003779 GO:0005737 GO:0008290 GO:0030036
DHO_dh	Dihydroorotate dehydrogenase	PF01180	IPR012135	GO:0004152 GO:0006222 GO:0055114
CK_II_beta	Casein kinase II regulatory subunit	PF01214	IPR000704	GO:0005956 GO:0019887
Porin_3	Eukaryotic porin	PF01459	IPR001925	GO:0005741 GO:0006820 GO:0008308 GO:0055085
Peptidase_M20	Peptidase family M20/M25/M40	PF01546	IPR002933	GO:0008152 GO:0016787
IF4E	Eukaryotic initiation factor 4E	PF01652	IPR001040	GO:0003723 GO:0003743 GO:0005737 GO:0006413
Thi4	Thi4 family	PF01946
Peptidase_M18	Aminopeptidase I zinc metalloprotease (M18)	PF02127	IPR001948	GO:0004177 GO:0005773 GO:0006508 GO:0008270
TPP_enzyme_N	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	PF02776	IPR012001	GO:0030976
FAD-oxidase_C	FAD linked oxidases, C-terminal domain	PF02913	IPR004113	GO:0003824 GO:0050660
Y_phosphatase2	Tyrosine phosphatase family	PF03162	IPR004861
YIF1	YIF1	PF03878	IPR005578
Vps52	Vps52 / Sac2 family	PF04129	IPR007258
UNC-50	UNC-50 family	PF05216	IPR007881
SNARE	SNARE domain	PF05739	IPR000727
Pkinase_Tyr	Protein tyrosine kinase	PF07714	IPR001245	GO:0004672 GO:0005524 GO:0006468
TFIIB_Zn_Ribbon	TFIIB zinc-binding	PF08271	IPR013137	GO:0008270 GO:0045449
Miro	Miro-like protein	PF08477	IPR013684	GO:0005525 GO:0005622 GO:0007264
AAA	ATPase family associated with various cellular activities (AAA)	PF00004	IPR003959	GO:0005524
GTP_EFTU	Elongation factor Tu GTP binding domain	PF00009	IPR000795	GO:0003924 GO:0005525
HSP20	Hsp20/alpha crystallin family	PF00011	IPR002068
SH2	SH2 domain	PF00017	IPR000980	GO:0005515
cNMP_binding	Cyclic nucleotide-binding domain	PF00027	IPR000595
GST_C	Glutathione S-transferase, C-terminal domain	PF00043	IPR004046
Myosin_head	Myosin head (motor domain)	PF00063	IPR001609	GO:0003774 GO:0005524 GO:0016459
RRM_1	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	PF00076	IPR000504	GO:0003676
Trypsin	Trypsin	PF00089	IPR001254	GO:0004252 GO:0006508
zf-C2H2	Zinc finger, C2H2 type	PF00096	IPR007087	GO:0005622 GO:0008270
zf-C3HC4	Zinc finger, C3HC4 type (RING finger)	PF00097	IPR018957
adh_short	short chain dehydrogenase	PF00106	IPR002198	GO:0008152 GO:0016491
Thiolase_N	Thiolase, N-terminal domain	PF00108	IPR020616	GO:0008152 GO:0016747
C1_1	Phorbol esters/diacylglycerol binding domain (C1 domain)	PF00130	IPR002219	GO:0023034
Pro_isomerase	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	PF00160	IPR002130	GO:0003755 GO:0006457
Cpn10	Chaperonin 10 Kd subunit	PF00166	IPR020818	GO:0005737 GO:0006457
bZIP_1	bZIP transcription factor	PF00170	IPR011616	GO:0003700 GO:0006355 GO:0043565 GO:0046983
Ets	Ets-domain	PF00178	IPR000418	GO:0003700 GO:0006355 GO:0043565
Iso_dh	Isocitrate/isopropylmalate dehydrogenase	PF00180	IPR001804	GO:0000287 GO:0016616 GO:0051287 GO:0055114
HSP90	Hsp90 protein	PF00183	IPR020576
UDPGT	UDP-glucoronosyl and UDP-glucosyl transferase	PF00201	IPR002213	GO:0008152 GO:0016758
Guanylate_cyc	Adenylate and Guanylate cyclase catalytic domain	PF00211	IPR001054	GO:0009190 GO:0016849 GO:0023034
DnaJ	DnaJ domain	PF00226	IPR001623	GO:0031072
MIP	Major intrinsic protein	PF00230	IPR000425	GO:0005215 GO:0006810 GO:0016020
ubiquitin	Ubiquitin family	PF00240	IPR000626
Flavodoxin_1	Flavodoxin	PF00258	IPR008254	GO:0010181 GO:0016491
Ribonuc_red_sm	Ribonucleotide reductase, small chain	PF00268	IPR000358	GO:0004748 GO:0009186 GO:0055114
DEAD	DEAD/DEAH box helicase	PF00270	IPR011545	GO:0003676 GO:0005524 GO:0008026
Helicase_C	Helicase conserved C-terminal domain	PF00271	IPR001650	GO:0003676 GO:0004386 GO:0005524
PALP	Pyridoxal-phosphate dependent enzyme	PF00291	IPR001926	GO:0003824 GO:0008152 GO:0030170
FBPase	Fructose-1-6-bisphosphatase	PF00316	IPR000146	GO:0005975 GO:0042578
Aconitase	Aconitase family (aconitate hydratase)	PF00330	IPR001030	GO:0008152
NDK	Nucleoside diphosphate kinase	PF00334	IPR001564	GO:0004550 GO:0005524 GO:0006183 GO:0006228 GO:0006241
WW	WW domain	PF00397	IPR001202	GO:0005515
WD40	WD domain, G-beta repeat	PF00400	IPR019781
LIM	LIM domain	PF00412	IPR001781	GO:0008270
Bromodomain	Bromodomain	PF00439	IPR001487
UCH	Ubiquitin carboxyl-terminal hydrolase	PF00443	IPR001394	GO:0004221 GO:0006511
PP2C	Protein phosphatase 2C	PF00481	IPR014045
PRK	Phosphoribulokinase / Uridine kinase family	PF00485	IPR006083	GO:0005524 GO:0008152 GO:0016301
ALAD	Delta-aminolevulinic acid dehydratase	PF00490	IPR001731	GO:0004655 GO:0033014 GO:0046872
G-alpha	G-protein alpha subunit	PF00503	IPR001019	GO:0004871 GO:0007186 GO:0019001
CBS	CBS domain pair	PF00571	IPR000644
Rhodanese	Rhodanese-like domain	PF00581	IPR001763
Acetyltransf_1	Acetyltransferase (GNAT) family	PF00583	IPR022610
FCH	Fes/CIP4 homology domain	PF00611	IPR001060
UBA	UBA/TS-N domain	PF00627	IPR000449
HECT	HECT-domain (ubiquitin-transferase)	PF00632	IPR000569	GO:0005622 GO:0006464 GO:0016881
BTB	BTB/POZ domain	PF00651	IPR013069	GO:0005515
SRP1_TIP1	Seripauperin and TIP1 family	PF00660	IPR000992	GO:0006950
Peptidase_M16	Insulinase (Peptidase family M16)	PF00675	IPR011765	GO:0004222 GO:0006508
E1_dh	Dehydrogenase E1 component	PF00676	IPR001017	GO:0008152 GO:0016624
dUTPase	dUTPase	PF00692	IPR008180	GO:0016787 GO:0046080
Aconitase_C	Aconitase C-terminal domain	PF00694	IPR000573	GO:0008152
Asparaginase	Asparaginase	PF00710	IPR006034	GO:0006520
EF1_GNE	EF-1 guanine nucleotide exchange domain	PF00736	IPR014038	GO:0003746 GO:0005853 GO:0006414
XPG_N	XPG N-terminal domain	PF00752	IPR006085	GO:0004518 GO:0006281
RNB	RNB domain	PF00773	IPR001900	GO:0003723 GO:0004540
DAGK_cat	Diacylglycerol kinase catalytic domain	PF00781	IPR001206	GO:0004143 GO:0007205
DSPc	Dual specificity phosphatase, catalytic domain	PF00782	IPR000340	GO:0006470 GO:0008138
ILVD_EDD	Dehydratase family	PF00920	IPR000581	GO:0003824 GO:0008152
Sec1	Sec1 family	PF00995	IPR001619	GO:0006904 GO:0016192
Cys_Met_Meta_PP	Cys/Met metabolism PLP-dependent enzyme	PF01053	IPR000277	GO:0006520 GO:0030170
Hint	Hint module	PF01079	IPR001767	GO:0006508 GO:0008233
HH_signal	Hedgehog amino-terminal signalling domain	PF01085	IPR000320	GO:0007267 GO:0007275
TFIIS_C	Transcription factor S-II (TFIIS)	PF01096	IPR001222	GO:0003676 GO:0008270 GO:0030528 GO:0045449
GTP_cyclohydroI	GTP cyclohydrolase I	PF01227	IPR020602
CAP_GLY	CAP-Gly domain	PF01302	IPR000938
mRNA_cap_enzyme	mRNA capping enzyme, catalytic domain	PF01331	IPR001339	GO:0004484 GO:0006370 GO:0006397
Skp1	Skp1 family, dimerisation domain	PF01466	IPR016072	GO:0006511
PUA	PUA domain	PF01472	IPR002478	GO:0003723
P_proprotein	Proprotein convertase P-domain	PF01483	IPR002884	GO:0004252 GO:0006508
V_ATPase_I	V-type ATPase 116kDa subunit family	PF01496	IPR002490	GO:0015078 GO:0015986 GO:0033177
Glyco_hydro_47	Glycosyl hydrolase family 47	PF01532	IPR001382	GO:0004571 GO:0005509 GO:0016020
FAD_binding_4	FAD binding domain	PF01565	IPR006094	GO:0016491 GO:0050660
Choline_kinase	Choline/ethanolamine kinase	PF01633	IPR002573
FtsJ	FtsJ-like methyltransferase	PF01728	IPR002877	GO:0003676 GO:0008168 GO:0032259
IBB	Importin beta binding domain	PF01749	IPR002652	GO:0005634 GO:0005643 GO:0005737 GO:0006606 GO:0006886 GO:0008565
RRF	Ribosome recycling factor	PF01765	IPR002661	GO:0006412
NIF3	NIF3 (NGG1p interacting factor 3)	PF01784	IPR002678
Glyco_transf_15	Glycolipid 2-alpha-mannosyltransferase	PF01793	IPR002685	GO:0004377 GO:0006486 GO:0016020
Ferric_reduct	Ferric reductase like transmembrane component	PF01794	IPR013130	GO:0005506 GO:0009055 GO:0016021 GO:0016491 GO:0050660
FF	FF domain	PF01846	IPR002713
NAC	NAC domain	PF01849	IPR002715
SIR2	Sir2 family	PF02146	IPR003000	GO:0006342 GO:0006476 GO:0008270 GO:0016811 GO:0045449 GO:0070403
RNA_POL_M_15KD	RNA polymerases M/15 Kd subunit	PF02150	IPR001529	GO:0003677 GO:0003899 GO:0006350
zf-TRAF	TRAF-type zinc finger	PF02176
RIIa	Regulatory subunit of type II PKA R-subunit	PF02197	IPR003117	GO:0007165 GO:0008603
SAM_PNT	Sterile alpha motif (SAM)/Pointed domain	PF02198	IPR003118	GO:0005634 GO:0043565
E2F_TDP	E2F/DP family winged-helix DNA-binding domain	PF02319	IPR003316	GO:0003700 GO:0005667 GO:0006355
Glucan_synthase	1,3-beta-glucan synthase component	PF02364	IPR003440	GO:0000148 GO:0003843 GO:0006075 GO:0016020
HATPase_c	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	PF02518	IPR003594	GO:0005524
Pantoate_transf	Ketopantoate hydroxymethyltransferase	PF02548	IPR003700	GO:0003864 GO:0015940
TPP_enzyme_C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	PF02775	IPR011766	GO:0003824 GO:0030976
Transket_pyr	Transketolase, pyrimidine binding domain	PF02779	IPR005475
GRAM	GRAM domain	PF02893	IPR004182
Peptidase_C1_2	Peptidase C1-like family	PF03051	IPR004134	GO:0004197 GO:0006508
BPL_LipA_LipB	Biotin/lipoate A/B protein ligase family	PF03099	IPR004143	GO:0003824 GO:0006464
MH1	MH1 domain	PF03165	IPR003619	GO:0005622 GO:0006355
MH2	MH2 domain	PF03166	IPR001132	GO:0005622 GO:0006355
PRA1	PRA1 family protein	PF03208	IPR004895
V-ATPase_C	V-ATPase subunit C	PF03223	IPR004907	GO:0015986 GO:0016820 GO:0033180
FTR1	Iron permease FTR1 family	PF03239	IPR004923	GO:0016020 GO:0055085
PMM	Eukaryotic phosphomannomutase	PF03332	IPR005002	GO:0004615 GO:0005737 GO:0019307
Snf7	Snf7	PF03357	IPR005024	GO:0015031
Saccharop_dh	Saccharopine dehydrogenase	PF03435	IPR005097
Tmemb_14	Transmembrane proteins 14C	PF03647	IPR005349	GO:0016020
UPF0160	Uncharacterised protein family (UPF0160)	PF03690	IPR003226
mRNA_cap_C	mRNA capping enzyme, C-terminal domain	PF03919	IPR013846
Skp1_POZ	Skp1 family, tetramerisation domain	PF03931	IPR016073	GO:0006511
Sec34	Sec34-like family	PF04136	IPR007265	GO:0005801 GO:0006886 GO:0016020
Mog1	Ran-interacting Mog1 protein	PF04603	IPR007681
SIP1	Survival motor neuron (SMN) interacting protein 1 (SIP1)	PF04938
Dpy-30	Dpy-30 motif	PF05186	IPR007858
GMP_PDE_delta	GMP-PDE, delta subunit	PF05351	IPR008015
Ran-binding	RanGTP-binding protein	PF05508	IPR008812
SOCS_box	SOCS box	PF07525	IPR001496	GO:0023034
DUF1712	Fungal domain of unknown function (DUF1712)	PF08217	IPR013176
NBP1	Fungal Nap binding protein NBP1	PF08537	IPR013743
TFIIH_BTF_p62_N	TFIIH p62 subunit, N-terminal domain	PF08567	IPR013876
Vps51	Vps51/Vps67	PF08700	IPR014812
Rgp1	Rgp1	PF08737	IPR014848