SH2

• Pfam ID: SH2
• Description: SH2 domain
• Accession: PF00017
• Interpro ID: IPR000980
• GO ID:

  GO:0005515

SH2 forms interactions with

Pfam ID	Description	Accession	Interpro ID	GO ID	Notes	Source
SH2	SH2 domain	PF00017	IPR000980	GO:0005515
SH3_1	SH3 domain	PF00018	IPR001452
fn3	Fibronectin type III domain	PF00041	IPR003961
Y_phosphatase	Protein-tyrosine phosphatase	PF00102	IPR000242	GO:0004725 GO:0006470
C1_1	Phorbol esters/diacylglycerol binding domain (C1 domain)	PF00130	IPR002219	GO:0023034
PI3Ka	Phosphoinositide 3-kinase family, accessory domain (PIK domain)	PF00613	IPR001263	GO:0004428
PI3K_C2	Phosphoinositide 3-kinase C2	PF00792	IPR002420	GO:0005942 GO:0016303 GO:0046854 GO:0048015
ITAM	Immunoreceptor tyrosine-based activation motif	PF02189	IPR003110	GO:0004888 GO:0007166 GO:0016020
STAT_bind	STAT protein, DNA binding domain	PF02864	IPR013801	GO:0003700 GO:0004871 GO:0005634 GO:0006355 GO:0007165
SOCS_box	SOCS box	PF07525	IPR001496	GO:0023034
SH3_2	Variant SH3 domain	PF07653	IPR011511
Pkinase_Tyr	Protein tyrosine kinase	PF07714	IPR001245	GO:0004672 GO:0005524 GO:0006468
7tm_1	7 transmembrane receptor (rhodopsin family)	PF00001	IPR000276	GO:0007186 GO:0016021
KH_1	KH domain	PF00013	IPR018111	GO:0003723
Ank	Ankyrin repeat	PF00023	IPR002110
ig	Immunoglobulin domain	PF00047	IPR013151
Pkinase	Protein kinase domain	PF00069	IPR017442	GO:0004672 GO:0005524 GO:0006468
C2	C2 domain	PF00168	IPR000008
PH	PH domain	PF00169	IPR001849
PI-PLC-Y	Phosphatidylinositol-specific phospholipase C, Y domain	PF00387	IPR001711	GO:0004435 GO:0006629 GO:0007165 GO:0023034
PI-PLC-X	Phosphatidylinositol-specific phospholipase C, X domain	PF00388	IPR000909	GO:0004629 GO:0006629 GO:0023034
Pkinase_C	Protein kinase C terminal domain	PF00433	IPR017892	GO:0004674 GO:0005524 GO:0006468
RhoGAP	RhoGAP domain	PF00620	IPR000198	GO:0005622 GO:0007165
RhoGEF	RhoGEF domain	PF00621	IPR000219	GO:0005089 GO:0005622 GO:0035023
PID	Phosphotyrosine interaction domain (PTB/PID)	PF00640	IPR006020
BTK	BTK motif	PF00779	IPR001562	GO:0023034
STAT_alpha	STAT protein, all-alpha domain	PF01017	IPR013800	GO:0003700 GO:0004871 GO:0005634 GO:0006355 GO:0007165
IRS	PTB domain (IRS-1 type)	PF02174	IPR002404	GO:0005158
RBD	Raf-like Ras-binding domain	PF02196	IPR003116	GO:0005057 GO:0007165
Cbl_N	CBL proto-oncogene N-terminal domain 1	PF02262	IPR003153	GO:0004871 GO:0005634 GO:0007166
Cbl_N2	CBL proto-oncogene N-terminus, EF hand-like domain	PF02761	IPR014741	GO:0004871 GO:0005634 GO:0007166
Cbl_N3	CBL proto-oncogene N-terminus, SH2-like domain	PF02762	IPR014742	GO:0004871 GO:0005634 GO:0007166
Focal_AT	Focal adhesion targeting region	PF03623	IPR005189	GO:0004713 GO:0004871 GO:0005925 GO:0006468 GO:0007172
V-set	Immunoglobulin V-set domain	PF07686	IPR013106
RA	Ras association (RalGDS/AF-6) domain	PF00788	IPR000159	GO:0007165
UPAR_LY6	u-PAR/Ly-6 domain	PF00021	IPR001526
Actin	Actin	PF00022	IPR004000	GO:0005515
Ras	Ras family	PF00071	IPR013753
Histone	Core histone H2A/H2B/H3/H4	PF00125	IPR007125	GO:0003677
bZIP_1	bZIP transcription factor	PF00170	IPR011616	GO:0003700 GO:0006355 GO:0043565 GO:0046983
NUDIX	NUDIX domain	PF00293	IPR000086	GO:0016787
Ribosomal_L3	Ribosomal protein L3	PF00297	IPR000597	GO:0003735 GO:0005622 GO:0005840 GO:0006412
CH	Calponin homology (CH) domain	PF00307	IPR001715
Bromodomain	Bromodomain	PF00439	IPR001487
UCH	Ubiquitin carboxyl-terminal hydrolase	PF00443	IPR001394	GO:0004221 GO:0006511
HMG_box	HMG (high mobility group) box	PF00505	IPR000910	GO:0003677 GO:0005634
SRCR	Scavenger receptor cysteine-rich domain	PF00530	IPR001190	GO:0005044 GO:0016020
S1	S1 RNA binding domain	PF00575	IPR003029	GO:0003723
FCH	Fes/CIP4 homology domain	PF00611	IPR001060
IQ	IQ calmodulin-binding motif	PF00612	IPR000048
RasGAP	GTPase-activator protein for Ras-like GTPase	PF00616	IPR001936	GO:0005096 GO:0005622 GO:0051056
UBA	UBA/TS-N domain	PF00627	IPR000449
Furin-like	Furin-like cysteine rich region	PF00757	IPR006211	GO:0004714 GO:0005524 GO:0006468 GO:0007169 GO:0016020
Recep_L_domain	Receptor L domain	PF01030	IPR000494	GO:0016020
SAM_PNT	Sterile alpha motif (SAM)/Pointed domain	PF02198	IPR003118	GO:0005634 GO:0043565
VPS9	Vacuolar sorting protein 9 (VPS9) domain	PF02204	IPR003123
Retro_M	Retroviral M domain	PF02813	IPR004028
zf-BED	BED zinc finger	PF02892	IPR003656	GO:0003677
zf-Tim10_DDP	Tim10/DDP family zinc finger	PF02953	IPR004217	GO:0006626 GO:0042719 GO:0045039
Exo_endo_phos	Endonuclease/Exonuclease/phosphatase family	PF03372	IPR005135
UPF0172	Uncharacterised protein family (UPF0172)	PF03665	IPR005366
Lep_receptor_Ig	Ig-like C2-type domain	PF06328	IPR010457