Pfam ID Description Accession Interpro ID GO ID
SH3_1 SH3 domain PF00018 IPR001452



SH3_1 forms interactions with

Pfam ID Description Accession Interpro ID GO ID Notes Source
SH2 SH2 domain PF00017 IPR000980
GO:0005515
 PDB IPFAM 3DID ME FUSION PE KGIDDI
SH3_1 SH3 domain PF00018 IPR001452
PDB IPFAM 3DID ME RCDP PE RDFF
Ank Ankyrin repeat PF00023 IPR002110
PDB IPFAM 3DID ME FUSION
PH PH domain PF00169 IPR001849
PDB 3DID ME FUSION RDFF
ubiquitin Ubiquitin family PF00240 IPR000626
PDB 3DID RDFF
LIM LIM domain PF00412 IPR001781
GO:0008270
 PDB IPFAM FUSION
F-protein Negative factor, (F-Protein) or Nef PF00469 IPR001558
GO:0005525
 PDB IPFAM 3DID
PB1 PB1 domain PF00564 IPR000270
PDB 3DID ME FUSION GPE
FCH Fes/CIP4 homology domain PF00611 IPR001060
PDB 3DID FUSION GPE
RhoGEF RhoGEF domain PF00621 IPR000219
GO:0005089
GO:0005622
GO:0035023
 PDB 3DID ME FUSION RDFF
Guanylate_kin Guanylate kinase PF00625 IPR008144
PDB IPFAM 3DID ME FUSION
Ca_channel_B Dihydropyridine sensitive L-type calcium channel (Beta subunit) PF00774
PDB IPFAM FUSION
P53 P53 DNA-binding domain PF00870 IPR011615
GO:0003677
GO:0003700
GO:0005634
GO:0006355
 PDB IPFAM 3DID
Myc_N Myc amino-terminal region PF01056 IPR012682
GO:0003700
GO:0005634
GO:0006355
 PDB IPFAM
Pex14_N Peroxisomal membrane anchor protein (Pex14p) conserved region PF04695 IPR006785
GO:0005777
GO:0016020
 PDB IPFAM
Cytochrom_B558a Cytochrome Cytochrome b558 alpha-subunit PF05038 IPR007732
GO:0020037
 PDB IPFAM
SAMP SAMP Motif PF05924 IPR009224
GO:0005515
GO:0016055
 PDB 3DID
SH3_2 Variant SH3 domain PF07653 IPR011511
PDB 3DID
Pkinase_Tyr Protein tyrosine kinase PF07714 IPR001245
GO:0004672
GO:0005524
GO:0006468
 PDB IPFAM 3DID KGIDDI
p47_phox_C NADPH oxidase subunit p47Phox, C terminal domain PF08944 IPR015039
PDB IPFAM 3DID
efhand EF hand PF00036 IPR018248
HCP ME FUSION RDFF
ig Immunoglobulin domain PF00047 IPR013151
HCP ME FUSION
Myosin_head Myosin head (motor domain) PF00063 IPR001609
GO:0003774
GO:0005524
GO:0016459
 HCP ME FUSION GPE
Pkinase Protein kinase domain PF00069 IPR017442
GO:0004672
GO:0005524
GO:0006468
 HCP FUSION RDFF INSITE DOMAINGA
Ras Ras family PF00071 IPR013753
HCP ME
Y_phosphatase Protein-tyrosine phosphatase PF00102 IPR000242
GO:0004725
GO:0006470
 HCP ME
C2 C2 domain PF00168 IPR000008
HCP ME PVALUE FUSION PE RDFF
2-oxoacid_dh 2-oxoacid dehydrogenases acyltransferase (catalytic domain) PF00198 IPR001078
GO:0008152
GO:0008415
 HCP PVALUE GPE RDFF
DnaJ DnaJ domain PF00226 IPR001623
GO:0031072
 HCP PE RDFF DOMAINGA
CH Calponin homology (CH) domain PF00307 IPR001715
HCP ME FUSION PE
WD40 WD domain, G-beta repeat PF00400 IPR019781
HCP ME RDFF DOMAINGA
Spectrin Spectrin repeat PF00435 IPR002017
HCP ME FUSION
Arginase Arginase family PF00491 IPR006035
GO:0016813
GO:0046872
 HCP PE GPE RDFF INSITE
WH1 WH1 domain PF00568 IPR000697
HCP GPE RDFF KGIDDI
PDZ PDZ domain (Also known as DHR or GLGF) PF00595 IPR001478
GO:0005515
 HCP ME FUSION
IQ IQ calmodulin-binding motif PF00612 IPR000048
HCP ME FUSION RDFF KGIDDI
RasGAP GTPase-activator protein for Ras-like GTPase PF00616 IPR001936
GO:0005096
GO:0005622
GO:0051056
 HCP ME FUSION
RasGEF RasGEF domain PF00617 IPR001895
GO:0005085
GO:0005622
GO:0007264
 HCP PVALUE FUSION GPE RDFF
RasGEF_N Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif PF00618 IPR000651
GO:0005085
GO:0005622
GO:0051056
 HCP ME PVALUE FUSION RDFF
RhoGAP RhoGAP domain PF00620 IPR000198
GO:0005622
GO:0007165
 HCP ME FUSION RDFF
PBD P21-Rho-binding domain PF00786 IPR000095
HCP ME PE RDFF KGIDDI
PX PX domain PF00787 IPR001683
GO:0005515
GO:0007154
GO:0035091
 HCP ME FUSION RDFF
ArfGap Putative GTPase activating protein for Arf PF01412 IPR001164
GO:0008060
GO:0008270
GO:0032312
 HCP ME FUSION PE RDFF
Pyr_redox_dim Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain PF02852 IPR004099
GO:0005737
GO:0016491
GO:0045454
GO:0050660
GO:0055114
 HCP PVALUE GPE RDFF
BAR BAR domain PF03114 IPR004148
GO:0005515
GO:0005737
 HCP FUSION PE GPE
HSP70 Hsp70 protein PF00012 IPR013126
MCP PE RDFF
Actin Actin PF00022 IPR004000
GO:0005515
 MCP PE RDFF INSITE
zf-C2H2 Zinc finger, C2H2 type PF00096 IPR007087
GO:0005622
GO:0008270
 MCP RDFF DOMAINGA
ADH_zinc_N Zinc-binding dehydrogenase PF00107 IPR013149
GO:0008270
GO:0016491
GO:0055114
 MCP PVALUE RDFF
C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain) PF00130 IPR002219
GO:0023034
 MCP FUSION KGIDDI
Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein PF00241 IPR002108
GO:0003779
GO:0005622
 MCP PVALUE FUSION
14-3-3 14-3-3 protein PF00244 IPR000308
GO:0019904
 MCP PE RDFF
PGAM Phosphoglycerate mutase family PF00300 IPR013078
MCP FUSION RDFF
UCH Ubiquitin carboxyl-terminal hydrolase PF00443 IPR001394
GO:0004221
GO:0006511
 MCP PE RDFF
TPR_1 Tetratricopeptide repeat PF00515 IPR001440
MCP FUSION DOMAINGA
UBA UBA/TS-N domain PF00627 IPR000449
MCP FUSION RDFF
VHS VHS domain PF00790 IPR002014
GO:0006886
 MCP FUSION GPE
PUF Pumilio-family RNA binding repeat PF00806 IPR001313
GO:0003723
 MCP PVALUE RDFF
DUF6 Integral membrane protein DUF6 PF00892 IPR000620
GO:0016020
 MCP PE GPE RDFF
NAP Nucleosome assembly protein (NAP) PF00956 IPR002164
GO:0005634
GO:0006334
 MCP PE RDFF
CAP_N Adenylate cyclase associated (CAP) N terminal PF01213 IPR013992
GO:0003779
GO:0007010
 MCP PE RDFF
I_LWEQ I/LWEQ domain PF01608 IPR002558
GO:0003779
 MCP GPE RDFF
UPF0057 Uncharacterized protein family UPF0057 PF01679 IPR000612
GO:0016021
 MCP PE GPE RDFF
Glyco_transf_15 Glycolipid 2-alpha-mannosyltransferase PF01793 IPR002685
GO:0004377
GO:0006486
GO:0016020
 MCP PE RDFF
SAP SAP domain PF02037 IPR003034
GO:0003676
 MCP PE RDFF
FH2 Formin Homology 2 Domain PF02181 IPR015425
MCP PE RDFF
WH2 WH2 motif PF02205 IPR003124
MCP PE RDFF
Syja_N SacI homology domain PF02383 IPR002013
MCP GPE RDFF
zf-MIZ MIZ/SP-RING zinc finger PF02891 IPR004181
GO:0008270
 MCP GPE RDFF
Glyco_hydro_81 Glycosyl hydrolase family 81 PF03639 IPR005200
GO:0016998
GO:0033903
 MCP PE GPE INSITE
DUF500 Family of unknown function (DUF500) PF04366 IPR007461
MCP DPEA GPE
ChaC ChaC-like protein PF04752 IPR006840
MCP PE GPE
UNC-50 UNC-50 family PF05216 IPR007881
MCP PE GPE
AAA ATPase family associated with various cellular activities (AAA) PF00004 IPR003959
GO:0005524
 LCP RDFF
GTP_EFTU Elongation factor Tu GTP binding domain PF00009 IPR000795
GO:0003924
GO:0005525
 LCP RDFF
fn3 Fibronectin type III domain PF00041 IPR003961
LCP FUSION
Gp_dh_N Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PF00044 IPR020828
LCP RDFF
Pyr_redox Pyridine nucleotide-disulphide oxidoreductase PF00070 IPR001327
GO:0016491
GO:0050660
GO:0055114
 LCP RDFF
Response_reg Response regulator receiver domain PF00072 IPR001789
GO:0000156
GO:0000160
GO:0006355
 LCP RDFF
RRM_1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PF00076 IPR000504
GO:0003676
 LCP RDFF
Sugar_tr Sugar (and other) transporter PF00083 IPR005828
GO:0005215
GO:0006810
GO:0016021
GO:0055085
 LCP RDFF
GATase Glutamine amidotransferase class-I PF00117 IPR000991
GO:0003824
 LCP PE
Histone Core histone H2A/H2B/H3/H4 PF00125 IPR007125
GO:0003677
 LCP RDFF
Metallophos Calcineurin-like phosphoesterase PF00149 IPR004843
GO:0016787
 LCP RDFF
Mito_carr Mitochondrial carrier protein PF00153 IPR018108
LCP DOMAINGA
Pro_isomerase Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PF00160 IPR002130
GO:0003755
GO:0006457
 LCP RDFF
bZIP_1 bZIP transcription factor PF00170 IPR011616
GO:0003700
GO:0006355
GO:0043565
GO:0046983
 LCP KGIDDI
Zn_clus Fungal Zn(2)-Cys(6) binuclear cluster domain PF00172 IPR001138
GO:0003700
GO:0005634
GO:0006355
GO:0008270
 LCP RDFF
NAD_binding_1 Oxidoreductase NAD-binding domain PF00175 IPR001433
GO:0016491
GO:0055114
 LCP RDFF
HSP90 Hsp90 protein PF00183 IPR020576
LCP GPE
DEAD DEAD/DEAH box helicase PF00270 IPR011545
GO:0003676
GO:0005524
GO:0008026
 LCP DOMAINGA
Helicase_C Helicase conserved C-terminal domain PF00271 IPR001650
GO:0003676
GO:0004386
GO:0005524
 LCP DOMAINGA
Ribosomal_L3 Ribosomal protein L3 PF00297 IPR000597
GO:0003735
GO:0005622
GO:0005840
GO:0006412
 LCP PE
GATA GATA zinc finger PF00320 IPR000679
GO:0003700
GO:0006355
GO:0008270
GO:0043565
 LCP RDFF
Biotin_lipoyl Biotin-requiring enzyme PF00364 IPR000089
LCP RDFF
HMG-CoA_red Hydroxymethylglutaryl-coenzyme A reductase PF00368 IPR002202
GO:0004420
GO:0015936
GO:0050662
GO:0055114
 LCP RDFF
PI-PLC-Y Phosphatidylinositol-specific phospholipase C, Y domain PF00387 IPR001711
GO:0004435
GO:0006629
GO:0007165
GO:0023034
 LCP FUSION
PI-PLC-X Phosphatidylinositol-specific phospholipase C, X domain PF00388 IPR000909
GO:0004629
GO:0006629
GO:0023034
 LCP FUSION
WW WW domain PF00397 IPR001202
GO:0005515
 LCP RDFF
PIR Yeast PIR protein repeat PF00399 IPR000420
LCP RDFF
Pkinase_C Protein kinase C terminal domain PF00433 IPR017892
GO:0004674
GO:0005524
GO:0006468
 LCP RDFF
Bromodomain Bromodomain PF00439 IPR001487
LCP KGIDDI
PP2C Protein phosphatase 2C PF00481 IPR014045
LCP PE
HMG_box HMG (high mobility group) box PF00505 IPR000910
GO:0003677
GO:0005634
 LCP RDFF
SAM_1 SAM domain (Sterile alpha motif) PF00536 IPR021129
LCP FUSION
RHD Rel homology domain (RHD) PF00554 IPR011539
GO:0003700
GO:0005634
GO:0045449
 LCP GPE
LRR_1 Leucine Rich Repeat PF00560 IPR001611
GO:0005515
 LCP RDFF
Abhydrolase_1 alpha/beta hydrolase fold PF00561 IPR000073
LCP RDFF
TBC TBC domain PF00566 IPR000195
GO:0005097
GO:0005622
GO:0032313
 LCP RDFF
Rhodanese Rhodanese-like domain PF00581 IPR001763
LCP RDFF
TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases PF00590 IPR000878
GO:0008152
GO:0008168
 LCP RDFF
HECT HECT-domain (ubiquitin-transferase) PF00632 IPR000569
GO:0005622
GO:0006464
GO:0016881
 LCP RDFF
PID Phosphotyrosine interaction domain (PTB/PID) PF00640 IPR006020
LCP FUSION
F-box F-box domain PF00646 IPR001810
LCP RDFF
Copper-fist Copper fist DNA binding domain PF00649 IPR001083
GO:0003677
GO:0003700
GO:0005507
GO:0005634
GO:0006355
 LCP RDFF
Peptidase_M16 Insulinase (Peptidase family M16) PF00675 IPR011765
GO:0004222
GO:0006508
 LCP RDFF
BTK BTK motif PF00779 IPR001562
GO:0023034
 LCP FUSION
MyTH4 MyTH4 domain PF00784 IPR000857
GO:0005856
 LCP FUSION
RA Ras association (RalGDS/AF-6) domain PF00788 IPR000159
GO:0007165
 LCP FUSION
ZU5 ZU5 domain PF00791 IPR000906
LCP FUSION
Syntaxin Syntaxin PF00804 IPR006011
GO:0016020
 LCP RDFF
Nebulin Nebulin repeat PF00880 IPR000900
LCP FUSION
FAD_binding_6 Oxidoreductase FAD-binding domain PF00970 IPR008333
GO:0016491
GO:0055114
 LCP RDFF
GDI GDP dissociation inhibitor PF00996 IPR018203
LCP RDFF
Clathrin_lg_ch Clathrin light chain PF01086 IPR000996
GO:0005198
GO:0005515
GO:0006886
GO:0016192
GO:0030130
GO:0030132
 LCP INSITE
GIDA Glucose inhibited division protein A PF01134 IPR002218
GO:0008033
GO:0050660
 LCP PVALUE
Ribosomal_L36e Ribosomal protein L36e PF01158 IPR000509
GO:0003735
GO:0005622
GO:0005840
GO:0006412
 LCP RDFF
Glucosamine_iso Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PF01182 IPR006148
GO:0005975
 LCP INSITE
CK_II_beta Casein kinase II regulatory subunit PF01214 IPR000704
GO:0005956
GO:0019887
 LCP PE
Ribosomal_L7Ae Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PF01248 IPR004038
LCP RDFF
ENTH ENTH domain PF01417 IPR001026
LCP RDFF
Peptidase_M1 Peptidase family M1 PF01433 IPR014782
GO:0008237
GO:0008270
 LCP PVALUE
IlvC Acetohydroxy acid isomeroreductase, catalytic domain PF01450 IPR000506
GO:0004455
GO:0009082
GO:0055114
 LCP RDFF
FAD_binding_4 FAD binding domain PF01565 IPR006094
GO:0016491
GO:0050660
 LCP RDFF
Adaptin_N Adaptin N terminal region PF01602 IPR002553
GO:0005515
GO:0006886
GO:0016192
GO:0030117
 LCP RDFF
IF4E Eukaryotic initiation factor 4E PF01652 IPR001040
GO:0003723
GO:0003743
GO:0005737
GO:0006413
 LCP RDFF
Rhomboid Rhomboid family PF01694
GO:0004252
GO:0016021
 LCP RDFF
AICARFT_IMPCHas AICARFT/IMPCHase bienzyme PF01808 IPR013982
GO:0003824
GO:0006188
 LCP INSITE
STE2 Fungal pheromone mating factor STE2 GPCR PF02116 IPR000366
GO:0004932
GO:0016020
 LCP INSITE
MGS MGS-like domain PF02142 IPR011607
LCP INSITE
HAT HAT (Half-A-TPR) repeat PF02184 IPR003107
GO:0005622
GO:0006396
 LCP RDFF
SWIB SWIB/MDM2 domain PF02201 IPR003121
LCP GPE
Sorb Sorbin homologous domain PF02208 IPR003127
LCP FUSION
Reticulon Reticulon PF02453 IPR003388
GO:0005783
 LCP INSITE
Tim17 Tim17/Tim22/Tim23 family PF02466 IPR003397
GO:0005743
GO:0008565
GO:0015031
 LCP RDFF
HATPase_c Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PF02518 IPR003594
GO:0005524
 LCP RDFF
Zip ZIP Zinc transporter PF02535 IPR003689
GO:0016020
GO:0030001
GO:0046873
GO:0055085
 LCP PE
Gp_dh_C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain PF02800 IPR020829
LCP RDFF
UIM Ubiquitin interaction motif PF02809 IPR003903
LCP FUSION
Retro_M Retroviral M domain PF02813 IPR004028
LCP FUSION
L27 L27 domain PF02828 IPR014775
LCP FUSION
FAD-oxidase_C FAD linked oxidases, C-terminal domain PF02913 IPR004113
GO:0003824
GO:0050660
 LCP RDFF
ATP_bind_1 Conserved hypothetical ATP binding protein PF03029 IPR004130
GO:0000166
 LCP INSITE
GTP_EFTU_D3 Elongation factor Tu C-terminal domain PF03143 IPR004160
GO:0005525
 LCP GPE
GTP_EFTU_D2 Elongation factor Tu domain 2 PF03144 IPR004161
GO:0005525
 LCP GPE
SHD1 SLA1 homology domain 1, SHD1 PF03983 IPR007131
LCP GPE
Tom22 Mitochondrial import receptor subunit Tom22 PF04281 IPR005683
GO:0005741
GO:0006886
 LCP INSITE
Peroxin-3 Peroxin-3 PF04882 IPR006966
GO:0005779
GO:0007031
 LCP INSITE
V-SNARE Vesicle transport v-SNARE protein PF05008 IPR007705
GO:0006886
GO:0016020
 LCP PE
MPPN MPPN (rrm-like) domain PF05172 IPR007846
LCP INSITE
RCSD RCSD region PF05177 IPR007850
LCP PE
Glycogen_syn Glycogen synthase PF05693 IPR008631
GO:0004373
GO:0005978
 LCP INSITE
Myosin_TH1 Myosin tail PF06017 IPR010926
GO:0003774
GO:0016459
 LCP FUSION
Drf_GBD Diaphanous GTPase-binding Domain PF06371 IPR010473
GO:0003779
GO:0017048
GO:0030036
 LCP GPE
Ded_cyto Dedicator of cytokinesis PF06920 IPR010703
GO:0005085
GO:0005525
GO:0051020
 LCP FUSION
EGF_CA Calcium binding EGF domain PF07645 IPR013091
LCP PE
HSCB_C HSCB C-terminal oligomerisation domain PF07743 IPR009073
GO:0005515
GO:0006457
 LCP PVALUE
Swi3 Replication Fork Protection Component Swi3 PF07962 IPR012923
GO:0005634
GO:0006974
GO:0007049
GO:0048478
 LCP INSITE
Rad33 Rad33 PF08730 IPR014841
LCP INSITE



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