RhoGEF

• Pfam ID: RhoGEF
• Description: RhoGEF domain
• Accession: PF00621
• Interpro ID: IPR000219
• GO ID:

  GO:0005089

  GO:0005622

  GO:0035023

RhoGEF forms interactions with

Pfam ID	Description	Accession	Interpro ID	GO ID	Notes	Source
SH3_1	SH3 domain	PF00018	IPR001452
Ras	Ras family	PF00071	IPR013753
Histone	Core histone H2A/H2B/H3/H4	PF00125	IPR007125	GO:0003677
C1_1	Phorbol esters/diacylglycerol binding domain (C1 domain)	PF00130	IPR002219	GO:0023034
PH	PH domain	PF00169	IPR001849
G-alpha	G-protein alpha subunit	PF00503	IPR001019	GO:0004871 GO:0007186 GO:0019001
RasGEF_N	Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif	PF00618	IPR000651	GO:0005085 GO:0005622 GO:0051056
RhoGEF	RhoGEF domain	PF00621	IPR000219	GO:0005089 GO:0005622 GO:0035023
SH3_2	Variant SH3 domain	PF07653	IPR011511
SH2	SH2 domain	PF00017	IPR000980	GO:0005515
Pkinase	Protein kinase domain	PF00069	IPR017442	GO:0004672 GO:0005524 GO:0006468
CH	Calponin homology (CH) domain	PF00307	IPR001715
PB1	PB1 domain	PF00564	IPR000270
PDZ	PDZ domain (Also known as DHR or GLGF)	PF00595	IPR001478	GO:0005515
FYVE	FYVE zinc finger	PF01363	IPR000306
RBD	Raf-like Ras-binding domain	PF02196	IPR003116	GO:0005057 GO:0007165
AAA	ATPase family associated with various cellular activities (AAA)	PF00004	IPR003959	GO:0005524
efhand	EF hand	PF00036	IPR018248
fn3	Fibronectin type III domain	PF00041	IPR003961
ig	Immunoglobulin domain	PF00047	IPR013151
Cpn60_TCP1	TCP-1/cpn60 chaperonin family	PF00118	IPR002423	GO:0005515 GO:0005524 GO:0044267
C2	C2 domain	PF00168	IPR000008
bZIP_1	bZIP transcription factor	PF00170	IPR011616	GO:0003700 GO:0006355 GO:0043565 GO:0046983
WD40	WD domain, G-beta repeat	PF00400	IPR019781
Spectrin	Spectrin repeat	PF00435	IPR002017
Bromodomain	Bromodomain	PF00439	IPR001487
BRCT	BRCA1 C Terminus (BRCT) domain	PF00533	IPR001357	GO:0005622
DEP	Domain found in Dishevelled, Egl-10, and Pleckstrin	PF00610	IPR000591	GO:0023034
IQ	IQ calmodulin-binding motif	PF00612	IPR000048
RasGEF	RasGEF domain	PF00617	IPR001895	GO:0005085 GO:0005622 GO:0007264
RhoGAP	RhoGAP domain	PF00620	IPR000198	GO:0005622 GO:0007165
Pyrophosphatase	Inorganic pyrophosphatase	PF00719	IPR008162	GO:0000287 GO:0004427 GO:0005737 GO:0006796
CNH	CNH domain	PF00780	IPR001180	GO:0005083
ENTH	ENTH domain	PF01417	IPR001026
SAM_PNT	Sterile alpha motif (SAM)/Pointed domain	PF02198	IPR003118	GO:0005634 GO:0043565
COG6	Conserved oligomeric complex COG6	PF06419	IPR010490
Pkinase_Tyr	Protein tyrosine kinase	PF07714	IPR001245	GO:0004672 GO:0005524 GO:0006468