Welcome to CancerRxTissue

We built predictive models for 272 drugs using data on gene expression from CCLE and drug sensitivity (IC50) from cancer cell lines from GDSC. We applied these predictive models to ~17,000 RNA-seq samples from TCGA and 5,894 RNA-seq samples from the GTEx to predict drug sensitivity for both normal and tumor tissues. You can query, visualize, and download the predicted IC50 values of the 272 drugs using ID, name, target or pathway.

Drug Sensitivity Predictions for The Cancer Genome Atlas (TCGA) RNA-seq data

Drug Sensitivity Predictions for GTEx RNA-seq data