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Organ Sites with Neoplasia

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  • Organ: Vascular System (Unspecified)
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Publication No. CASRN Test Article Name Species Sex Route Organ Level of Evidence Tumor Type/Incidence Finding Type
TR-029 129-15-7 2-Methyl-1-nitroanthraquinone Mice Female Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-029 129-15-7 2-Methyl-1-nitroanthraquinone Mice Male Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-100 135-20-6 Cupferron Mice Female Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOMA OR HEMANGIOSARCOMA Neoplastic Lesions
TR-100 135-20-6 Cupferron Mice Male Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-100 135-20-6 Cupferron Rats Female Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-100 135-20-6 Cupferron Rats Male Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-086 106-93-4 1,2-Dibromoethane Rats Male Gavage Vascular System (Unspecified) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-055 107-06-2 1,2-Dichloroethane Rats Male Gavage Vascular System (Unspecified) Positive (HEMANGIOSARCOMA) Neoplastic Lesions
TR-153 636-21-5 o-Toluidine hydrochloride Mice Male Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-165 3165-93-3 4-Chloro-o-toluidine hydrochloride Mice Female Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-165 3165-93-3 4-Chloro-o-toluidine hydrochloride Mice Male Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-181 90-94-8 Michler's ketone Mice Male Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-187 95-79-4 5-Chloro-o-toluidine Mice Female Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-107 99-55-8 5-Nitro-o-toluidine Mice Female Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-107 99-55-8 5-Nitro-o-toluidine Mice Male Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOMA OR HEMANGIOSARCOMA Neoplastic Lesions
TR-210 106-93-4 1,2-Dibromoethane Mice Female Inhalation Vascular System (Unspecified) Positive HEMANGIOSARCOMA 0/50 11/50 23/50 Neoplastic Lesions
TR-210 106-93-4 1,2-Dibromoethane Rats Female Inhalation Vascular System (Unspecified) Positive HEMANGIOSARCOMA 0/50 0/50 5/50 Neoplastic Lesions
TR-210 106-93-4 1,2-Dibromoethane Rats Male Inhalation Vascular System (Unspecified) Positive HEMANGIOSARCOMA 0/50 1/50 15/50 Neoplastic Lesions
TR-233 2185-92-4 2-Biphenylamine hydrochloride Mice Female Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOSARCOMA 0/49 1/50 7/50 Neoplastic Lesions
TR-251 26471-62-5 2,4- & 2,6-Toluene diisocyanate Mice Female Gavage Vascular System (Unspecified) Positive HEMANGIOMA 0/50 1/50 2/50 OR HEMANGIOSARCOMA 0/50 0/50 3/50 COMBINED 0/50 1/50 5/50 Neoplastic Lesions
TR-187 95-79-4 5-Chloro-o-toluidine Mice Male Dosed-Feed Vascular System (Unspecified) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-467 126-99-8 Chloroprene Mice Female Inhalation Vascular System (Unspecified) Clear Evidence HEMANGIOMA 0/50 0/50 2/50 3/50 OR HEMANGIOSARCOMA 4/50 6/50 17/50 5/50 COMBINED 4/50 6/50 18/50 8/50 Neoplastic Lesions
TR-467 126-99-8 Chloroprene Mice Male Inhalation Vascular System (Unspecified) Clear Evidence HEMANGIOMA 0/50 1/50 2/50 2/50 OR HEMANGIOSARCOMA 3/50 13/50 22/50 19/50 COMBINED 3/50 14/50 23/50 21/50 Neoplastic Lesions