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Organ Sites with Neoplasia

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  • Organ: Vascular System (Liver)
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Publication No. CASRN Test Article Name Species Sex Route Organ Level of Evidence Tumor Type/Incidence Finding Type
TR-026 1836-75-5 Nitrofen Mice Female Dosed-Feed Vascular System (Liver) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-026 1836-75-5 Nitrofen Mice Male Dosed-Feed Vascular System (Liver) Positive HEMANGIOSARCOMA Neoplastic Lesions
TR-349 87-86-5 Pentachlorophenol, Dowicide EC-7 Mice Female Dosed-Feed Vascular System (Liver) Clear Evidence HEMANGIOSARCOMA 0/34 1/50 1/49 8/48 Neoplastic Lesions
TR-349 87-86-5 Pentachlorophenol, technical Mice Female Dosed-Feed Vascular System (Liver) Some Evidence HEMANGIOSARCOMA 0/33 2/49 4/50 Neoplastic Lesions
TR-351 20265-96-7 p-Chloroaniline hydrochloride Mice Male Gavage Vascular System (Liver) Some Evidence HEMANGIOSARCOMA 2/50 2/50 1/49 6/50 Neoplastic Lesions
TR-414 1825-21-4 Pentachloroanisole Mice Male Gavage Vascular System (Liver) Some Evidence HEMANGIOSARCOMA 2/50 8/50 10/50 Neoplastic Lesions
TR-450 116-14-3 Tetrafluoroethylene Mice Female Inhalation Vascular System (Liver) Clear Evidence HEMANGIOMA 0/48 5/48 2/47 1/47 OR HEMANGIOSARCOMA 0/48 27/48 27/47 34/47 COMBINED 0/48 31/48 28/47 35/47 Neoplastic Lesions
TR-450 116-14-3 Tetrafluoroethylene Mice Male Inhalation Vascular System (Liver) Clear Evidence HEMANGIOMA 0/48 10/48 5/48 2/48 OR HEMANGIOSARCOMA 0/48 21/48 27/48 37/48 COMBINED 0/48 26/48 30/48 38/48 Neoplastic Lesions
TR-450 116-14-3 Tetrafluoroethylene Rats Female Inhalation Vascular System (Liver) Clear Evidence HEMANGIOSARCOMA 0/50 0/50 5/50 1/50 Neoplastic Lesions
TR-484 111-76-2 2-Butoxyethanol (ethylene glycol monobutyl ether) Mice Male Inhalation Vascular System (Liver) Some Evidence HEMANGIOSARCOMA 0/50 1/50 2/49 4/49 Neoplastic Lesions