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Organ Sites with Neoplasia

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  • Organ: Vascular System (Heart)
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Publication No. CASRN Test Article Name Species Sex Route Organ Level of Evidence Tumor Type/Incidence Finding Type
TR-288 106-99-0 1,3-Butadiene Mice Female Inhalation Vascular System (Heart) Clear Evidence HEMANGIOSARCOMA 0/50 11/48 18/49 Neoplastic Lesions
TR-288 106-99-0 1,3-Butadiene Mice Male Inhalation Vascular System (Heart) Clear Evidence HEMANGIOSARCOMA 0/50 16/49 7/49 Neoplastic Lesions
TR-434 106-99-0 1,3-Butadiene Mice Female Inhalation Vascular System (Heart) Clear Evidence HEMANGIOSARCOMA 0/50 0/50 0/50 1/49 21/50 23/80 Neoplastic Lesions
TR-434 106-99-0 1,3-Butadiene Mice Male Inhalation Vascular System (Heart) Clear Evidence HEMANGIOSARCOMA 0/50 0/49 1/50 5/48 20/48 4/73, STOP STUDY 15/50 7/50 33/50 13/50 Neoplastic Lesions