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Organ Sites with Neoplasia

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  • Organ: Uterus
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Publication No. CASRN Test Article Name Species Sex Route Organ Level of Evidence Tumor Type/Incidence Finding Type
TR-559 31508-00-6 TEF evaluation (PCB 118) Rats Female Gavage Uterus Clear Evidence Carcinoma 2/52 2/52 1/52 3/52 4/52 3/52 11/50 Neoplastic Lesions
TR-561 119-64-2 Tetralin Rats Female Inhalation Uterus Some Evidence Stromal polyp 6/50 10/50 9/50 17/50 Neoplastic Lesions
TR-587 79-94-7 Tetrabromobisphenol A Rats Female Gavage Uterus Clear Evidence adenoma (original transverse review) 0/50 0/50 3/50 4/50 adenocarcinoma (original transverse review) 3/50 3/50 8/50 9/50 )original transverse and residual longitudinal reviews, combined) 4/50 10/50 15/50 16/50 malignant mixed Müllerian tumor (original transverse review) 0/50 4/50 0/50 2/50 adenoma, adenocarcinoma, or malignant mixed Müllerian tumor (original transverse review) 3/50 7/50 11/50 13/50 )original transverse and residual longitudinal reviews, combined) 6/50 11/50 16/50 19/50 Neoplastic Lesions
TR-594 98-56-6 p-Chloro-a,a,a-trifluorotoluene Rats Female Inhalation Uterus Some Evidence adenocarcinoma (1/50, 1/50, 0/50, 5/50); stromal polyp (7/50, 9/50, 16/50, 12/50) Neoplastic Lesions
TR-576 15625-89-5 Trimethylolpropane triacrylate Mice Female Topical Application Uterus Some Evidence stromal polyp or stromal sarcoma 0/50, 1/50, 2/50, 6/50 Neoplastic Lesions