COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

Search Results

One moment please while the data are loaded...
View results
  • Organ: Urinary Bladder
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Displays results that match exactly with the given criteria.
Exact Match Publication No. CASRN Test Article Name Species Sex Route Organ Level of Evidence Tumor Type/Incidence Finding Type
Yes TR-006 139-13-9 Nitrilotriacetic acid (NTA) Rats Female Dosed-Feed Urinary Bladder Positive (TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-006 18662-53-8 Nitrilotriacetic acid trisodium monohydrate Rats Female Dosed-Feed Urinary Bladder Positive (TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-094 119-34-6 4-Amino-2-nitrophenol Rats Male Dosed-Feed Urinary Bladder Positive (TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-089 134-29-2 o-Anisidine hydrochloride Mice Female Dosed-Feed Urinary Bladder Positive (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-089 134-29-2 o-Anisidine hydrochloride Mice Male Dosed-Feed Urinary Bladder Positive (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-089 134-29-2 o-Anisidine hydrochloride Rats Female Dosed-Feed Urinary Bladder Positive (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-089 134-29-2 o-Anisidine hydrochloride Rats Male Dosed-Feed Urinary Bladder Positive (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-063 95-83-0 4-Chloro-o-phenylenediamine Rats Female Dosed-Feed Urinary Bladder Positive (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-063 95-83-0 4-Chloro-o-phenylenediamine Rats Male Dosed-Feed Urinary Bladder Positive (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-142 120-71-8 p-Cresidine Mice Female Dosed-Feed Urinary Bladder Positive (CARCINOMA) Neoplastic Lesions
Yes TR-142 120-71-8 p-Cresidine Mice Male Dosed-Feed Urinary Bladder Positive (CARCINOMA) Neoplastic Lesions
Yes TR-142 120-71-8 p-Cresidine Rats Female Dosed-Feed Urinary Bladder Positive (PAPILLOMA, CARCINOMA) Neoplastic Lesions
Yes TR-142 120-71-8 p-Cresidine Rats Male Dosed-Feed Urinary Bladder Positive (PAPILLOMA, CARCINOMA) Neoplastic Lesions
Yes TR-153 636-21-5 o-Toluidine hydrochloride Rats Female Dosed-Feed Urinary Bladder Positive (TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-164 86-30-6 N-Nitrosodiphenylamine Rats Female Dosed-Feed Urinary Bladder Positive (TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-164 86-30-6 N-Nitrosodiphenylamine Rats Male Dosed-Feed Urinary Bladder Positive (TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-179 105-11-3 p-Benzoquinone dioxime Rats Female Dosed-Feed Urinary Bladder Positive (TRANSITIONAL CELL PAPILLOMA OR CARCINOMA OR SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
Yes TR-105 102-50-1 m-Cresidine Rats Female Gavage Urinary Bladder Positive (TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-105 102-50-1 m-Cresidine Rats Male Gavage Urinary Bladder Positive (TRANSITIONAL CELL CARCINOMA) Neoplastic Lesions
Yes TR-216 2432-99-7 11-Aminoundecanoic acid Rats Male Dosed-Feed Urinary Bladder Positive TRANSITIONAL CELL CARCINOMA 0/48 0/48 7/49 Neoplastic Lesions
Yes TR-234 57-06-7 Allyl isothiocyanate Rats Male Gavage Urinary Bladder Positive TRANSITIONAL CELL PAPILLOMA 0/49 2/49 4/49 Neoplastic Lesions
Yes TR-245 108-78-1 Melamine Rats Male Dosed-Feed Urinary Bladder Positive TRANSITIONAL CELL CARCINOMA 0/45 0/50 8/49 Neoplastic Lesions
Yes TR-269 542-75-6 1,3-Dichloropropene (Telone II) Mice Female Gavage Urinary Bladder Clear Evidence TRANSITIONAL CELL CARCINOMA 0/50 8/50 21/48 Neoplastic Lesions
Yes TR-299 2475-45-8 C.I. Disperse blue 1 Rats Female Dosed-Feed Urinary Bladder Clear Evidence TRANSITIONAL CELL PAPILLOMA 0/48 0/50 9/50 15/48 OR TRANSITIONAL CELL CARCINOMA 0/48 0/50 10/50 13/48 COMBINED 0/48 0/50 15/50 21/48; LEIOMYOMA 0/48 0/50 1/50 4/48 OR LEIOMYOSARCOMA 0/48 0/50 2/50 23/48 COMBINED 0/48 0/50 3/50 26/48; SQUAMOUS CELL PAPILLOMA 0/48 0/50 1/50 7/48 OR SQUAMOUS CELL CARCINOMA 0/48 0/50 1/50 4/48 COMBINED 0/48 0/50 1/50 11/48 Neoplastic Lesions
Yes TR-299 2475-45-8 C.I. Disperse blue 1 Rats Male Dosed-Feed Urinary Bladder Clear Evidence TRANSITIONAL CELL PAPILLOMA 0/49 0/50 8/50 4/49 OR TRANSITIONAL CELL CARCINOMA 0/49 0/50 4/50 8/49 COMBINED 0/49 0/50 10/50 11/49; LEIOMYOMA 0/49 0/50 7/50 41/49 OR LEIOMYOSARCOMA 0/49 0/50 6/50 41/49 COMBINED 0/49 0/50 7/50 41/49; SQUAMOUS CELL PAPILLOMA 0/49 0/50 1/50 3/49 OR SQUAMOUS CELL CARCINOMA 0/49 0/50 1/50 1/49 COMBINED 0/49 0/50 2/50 4/49 Neoplastic Lesions
Yes TR-383 81-49-2 1-Amino-2,4-dibromoanthraquinone Rats Female Dosed-Feed Urinary Bladder Clear Evidence TRANSITIONAL CELL PAPILLOMA 0/50 2/40 7/60 9/46; TRANSITIONAL CELL CARCINOMA 0/50 0/40 8/60 16/46 Neoplastic Lesions
Yes TR-383 81-49-2 1-Amino-2,4-dibromoanthraquinone Rats Male Dosed-Feed Urinary Bladder Clear Evidence TRANSITIONAL CELL PAPILLOMA 0/50 1/38 2/58 8/50; TRANSITIONAL CELL CARCINOMA 0/50 0/38 1/58 4/50 Neoplastic Lesions
Yes TR-452 3296-90-0 2,2-bis(Bromomethyl)-1,3-propanediol Rats Male Dosed-Feed Urinary Bladder Clear Evidence TRANSITIONAL CELL PAPILLOMA 0/51 0/53 1/51 2/55 1/59 OR TRANSITIONAL CELL CARCINOMA 0/51 0/53 0/51 1/55 1/59 COMBINED 0/51 0/53 1/51 3/55 2/59 Neoplastic Lesions
Yes TR-457 599-79-1 Salicylazosulfapyridine Rats Female Gavage Urinary Bladder Some Evidence TRANSITIONAL CELL PAPILLOMA 0/49 0/50 2/50 0/50 Neoplastic Lesions
Yes TR-457 599-79-1 Salicylazosulfapyridine Rats Female Gavage Urinary Bladder Some Evidence TRANSITIONAL CELL PAPILLOMA 0/49 0/50 2/50 0/50 Neoplastic Lesions
Yes TR-457 599-79-1 Salicylazosulfapyridine Rats Male Gavage Urinary Bladder Some Evidence (CORE STUDY) TRANSITIONAL CELL PAPILLOMA 0/50 0/49 2/50 6/50 Neoplastic Lesions
Yes TR-457 599-79-1 Salicylazosulfapyridine Rats Male Gavage Urinary Bladder Some Evidence (CORE STUDY) TRANSITIONAL CELL PAPILLOMA 0/50 0/49 2/50 6/50 Neoplastic Lesions
Yes TR-416 91-23-6 o-Nitroanisole Rats Female Dosed-Feed Urinary Bladder Clear Evidence (STOP STUDY) TRANSITIONAL CELL PAPILLOMA 0/58 2/59 1/60, TRANSITIONAL CELL CARCINOMA 0/58 28/59 48/60 Neoplastic Lesions
Yes TR-416 91-23-6 o-Nitroanisole Rats Male Dosed-Feed Urinary Bladder Clear Evidence (STOP STUDY) TRANSITIONAL CELL PAPILLOMA 0/59 9/59 1/60, TRANSITIONAL CELL CARCINOMA 0/59 27/59 50/60, SQUAMOUS CELL PAPILLOMA 0/59 0/59 4/60, SQUAMOUS CELL CARCINOMA 0/59 0/59 6/60, SARCOMA 0/59 2/59 9/60 Neoplastic Lesions
Yes TR-494 84-65-1 Anthraquinone Rats Female Dosed-Feed Urinary Bladder Clear Evidence TRANSITIONAL EPITHELIAL PAPILLOMA OR CARCINOMA 0/49 0/49 0/49 1/50 2/49 Neoplastic Lesions
Yes TR-494 84-65-1 Anthraquinone Rats Male Dosed-Feed Urinary Bladder Some Evidence TRANSITIONAL EPITHELIAL PAPILLOMA 0/50 1/50 3/50 7/50 3/49 Neoplastic Lesions
Yes TR-563 89-82-7 Pulegone Rats Female Gavage Urinary Bladder Some Evidence Papilloma 0/50 0/49 1/50 3/47 papilloma or carcinoma 0/50 0/49 1/50 5/47 Neoplastic Lesions