Share This:

Organ Sites with Neoplasia

View results
  • Organ: Stomach, Forestomach
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Publication No. CASRN Test Article Name Species Sex Route Organ Level of Evidence Tumor Type/Incidence Finding Type
TR-028 96-12-8 1,2-Dibromo-3-chloropropane Mice Female Gavage Forestomach Positive (SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-028 96-12-8 1,2-Dibromo-3-chloropropane Mice Male Gavage Forestomach Positive (SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-028 96-12-8 1,2-Dibromo-3-chloropropane Rats Female Gavage Forestomach Positive (SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-028 96-12-8 1,2-Dibromo-3-chloropropane Rats Male Gavage Forestomach Positive (SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-086 106-93-4 1,2-Dibromoethane Mice Female Gavage Forestomach Positive (SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-086 106-93-4 1,2-Dibromoethane Mice Male Gavage Forestomach Positive (SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-095 6959-48-4 3-Chloromethylpyridine hydrochloride Mice Female Gavage Forestomach Positive (SQUAMOUS CELL PAPILLOMA OR CARCINOMA) Neoplastic Lesions
TR-095 6959-48-4 3-Chloromethylpyridine hydrochloride Mice Male Gavage Forestomach Positive (SQUAMOUS CELL PAPILLOMA OR CARCINOMA) Neoplastic Lesions
TR-095 6959-48-4 3-Chloromethylpyridine hydrochloride Rats Male Gavage Forestomach Positive (SQUAMOUS CELL PAPILLOMA OR CARCINOMA) Neoplastic Lesions
TR-100 135-20-6 Cupferron Rats Female Dosed-Feed Forestomach Positive SQUAMOUS CELL CARCINOMA Neoplastic Lesions
TR-086 106-93-4 1,2-Dibromoethane Rats Female Gavage Forestomach Positive (SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-086 106-93-4 1,2-Dibromoethane Rats Male Gavage Forestomach Positive SQUAMOUS CELL CARCINOMA Neoplastic Lesions
TR-034 1582-09-8 Trifluralin Mice Female Dosed-Feed Forestomach Positive (SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-055 107-06-2 1,2-Dichloroethane Rats Male Gavage Forestomach Positive (SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-059 22966-79-6 Estradiol mustard Mice Female Gavage Forestomach Positive (SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-059 22966-79-6 Estradiol mustard Mice Male Gavage Forestomach Positive (SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-063 95-83-0 4-Chloro-o-phenylenediamine Rats Female Dosed-Feed Forestomach Positive (SQUAMOUS CELL PAPILLOMA OR SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-063 95-83-0 4-Chloro-o-phenylenediamine Rats Male Dosed-Feed Forestomach Positive (SQUAMOUS CELL PAPILLOMA OR SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-076 126-72-7 tris(2,3-Dibromopropyl) phosphate Mice Female Dosed-Feed Forestomach Positive (SQUAMOUS CELL PAPILLOMA, SQUAMOUS CELL CARCINOMA) Neoplastic Lesions
TR-076 126-72-7 tris(2,3-Dibromopropyl) phosphate Mice Male Dosed-Feed Forestomach Positive (SQUAMOUS CELL PAPILLOMA, SQUAMOUS CELL PAPILLOMA OR CARCINOMA) Neoplastic Lesions
TR-115 95-06-7 Sulfallate Rats Male Dosed-Feed Forestomach Positive (SQUAMOUS CELL PAPILLOMA OR CARCINOMA) Neoplastic Lesions
TR-140 1955-45-9 Pivalolactone Rats Female Gavage Forestomach Positive (SQUAMOUS CELL PAPILLOMA OR CARCINOMA) Neoplastic Lesions
TR-140 1955-45-9 Pivalolactone Rats Male Gavage Forestomach Positive (SQUAMOUS CELL PAPILLOMA OR CARCINOMA) Neoplastic Lesions
TR-100 135-20-6 Cupferron Rats Male Dosed-Feed Forestomach Positive SQUAMOUS CELL CARCINOMA Neoplastic Lesions
TR-250 140-11-4 Benzyl acetate Mice Female Gavage Forestomach Some Evidence SQUAMOUS CELL PAPILLOMA 0/50 0/50 4/48 Neoplastic Lesions
TR-250 140-11-4 Benzyl acetate Mice Male Gavage Forestomach Some Evidence SQUAMOUS CELL PAPILLOMA 3/49 3/48 9/49 OR SQUAMOUS CELL CARCINOMA 1/49 1/48 2/49 COMBINED 4/49 4/48 11/49 Neoplastic Lesions
TR-257 101-90-6 Diglycidyl resorcinol ether (DGRE) Mice Female Gavage Forestomach Positive SQUAMOUS CELL PAPILLOMA 0/47 5/49 10/49; SQUAMOUS CELL CARCINOMA 0/47 12/49 23/49 Neoplastic Lesions
TR-257 101-90-6 Diglycidyl resorcinol ether (DGRE) Mice Male Gavage Forestomach Positive SQUAMOUS CELL PAPILLOMA 0/47 4/49 10/50; SQUAMOUS CELL CARCINOMA 0/47 14/49 25/50 Neoplastic Lesions
TR-257 101-90-6 Diglycidyl resorcinol ether (DGRE) Rats Female Gavage Forestomach Positive SQUAMOUS CELL PAPILLOMA 0/49 7/50 1/50; SQUAMOUS CELL CARCINOMA 0/49 34/50 3/50 Neoplastic Lesions
TR-257 101-90-6 Diglycidyl resorcinol ether (DGRE) Rats Male Gavage Forestomach Positive SQUAMOUS CELL PAPILLOMA 0/50 17/50 6/49; SQUAMOUS CELL CARCINOMA 0/50 38/50 4/49 Neoplastic Lesions
TR-259 140-88-5 Ethyl acrylate Mice Female Gavage Forestomach Positive SQUAMOUS CELL PAPILLOMA 1/50 4/49 5/48 OR SQUAMOUS CELL CARCINOMA 0/50 1/49 2/48 COMBINED 1/50 5/49 7/48 Neoplastic Lesions
TR-259 140-88-5 Ethyl acrylate Mice Male Gavage Forestomach Positive SQUAMOUS CELL PAPILLOMA 0/48 4/47 9/50 OR SQUAMOUS CELL CARCINOMA 0/48 2/47 5/50 COMBINED 0/48 5/47 12/50 Neoplastic Lesions
TR-259 140-88-5 Ethyl acrylate Rats Female Gavage Forestomach Positive SQUAMOUS CELL PAPILLOMA 1/50 6/50 9/50 OR SQUAMOUS CELL CARCINOMA 0/50 0/50 2/50 COMBINED 1/50 6/50 11/50 Neoplastic Lesions
TR-259 140-88-5 Ethyl acrylate Rats Male Gavage Forestomach Positive SQUAMOUS CELL PAPILLOMA 1/50 15/50 29/50 OR SQUAMOUS CELL CARCINOMA 0/50 5/50 12/50 COMBINED 1/50 18/50 36/50 Neoplastic Lesions
TR-269 542-75-6 1,3-Dichloropropene (Telone II) Mice Female Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 1/50 2/50 OR SQUAMOUS CELL CARCINOMA 0/50 0/50 2/50 COMBINED 0/50 1/50 4/50 Neoplastic Lesions
TR-269 542-75-6 1,3-Dichloropropene (Telone II) Rats Female Gavage Forestomach Some Evidence SQUAMOUS CELL PAPILLOMA 0/52 2/52 3/52 Neoplastic Lesions
TR-269 542-75-6 1,3-Dichloropropene (Telone II) Rats Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 1/52 1/52 9/52; SQUAMOUS CELL CARCINOMA 0/52 0/52 4/52 Neoplastic Lesions
TR-287 868-85-9 Dimethyl hydrogen phosphite Rats Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 1/50 3/50; SQUAMOUS CELL CARCINOMA 0/50 0/50 3/50 Neoplastic Lesions
TR-288 106-99-0 1,3-Butadiene Mice Female Inhalation Forestomach Clear Evidence PAPILLOMA 0/49 4/42 10/49 Neoplastic Lesions
TR-288 106-99-0 1,3-Butadiene Mice Male Inhalation Forestomach Clear Evidence PAPILLOMA 0/49 5/40 0/44 Neoplastic Lesions
TR-300 563-47-3 3-Chloro-2-methylpropene Mice Female Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 15/48 29/44; SQUAMOUS CELL CARCINOMA 0/50 1/48 2/44 Neoplastic Lesions
TR-300 563-47-3 3-Chloro-2-methylpropene Mice Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 3/49 19/49 30/49; SQUAMOUS CELL CARCINOMA 0/49 5/49 7/49 Neoplastic Lesions
TR-300 563-47-3 3-Chloro-2-methylpropene Rats Female Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 1/50 1/50 10/50 Neoplastic Lesions
TR-300 563-47-3 3-Chloro-2-methylpropene Rats Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 1/50 5/50 30/48; SQUAMOUS CELL CARCINOMA 0/50 0/50 2/48 Neoplastic Lesions
TR-316 513-37-1 Dimethylvinyl chloride (DMVC) Mice Female Gavage Forestomach Clear Evidence SQUAMOUS CELL CARCINOMA 0/50 40/47 36/43 Neoplastic Lesions
TR-316 513-37-1 Dimethylvinyl chloride (DMVC) Mice Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 1/48 3/47 8/44; SQUAMOUS CELL CARCINOMA 0/48 42/47 35/44 Neoplastic Lesions
TR-316 513-37-1 Dimethylvinyl chloride (DMVC) Rats Female Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 1/50 4/50 1/49 OR SQUAMOUS CELL CARCINOMA 0/50 5/50 1/49 COMBINED 1/50 9/50 2/49 Neoplastic Lesions
TR-316 513-37-1 Dimethylvinyl chloride (DMVC) Rats Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/49 7/50 0/50; SQUAMOUS CELL CARCINOMA 0/49 7/50 0/50 Neoplastic Lesions
TR-374 556-52-5 Glycidol Mice Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 2/50 9/50 OR SQUAMOUS CELL CARCINOMA 1/50 0/50 1/50 COMBINED 1/50 2/50 10/50 Neoplastic Lesions
TR-374 556-52-5 Glycidol Rats Female Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 4/50 8/50 OR SQUAMOUS CELL CARCINOMA 0/50 0/50 3/50 COMBINED 0/50 4/50 11/50 Neoplastic Lesions
TR-374 556-52-5 Glycidol Rats Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 1/50 5/50 OR SQUAMOUS CELL CARCINOMA 1/50 1/50 2/50 COMBINED 1/50 2/50 6/50 Neoplastic Lesions
TR-378 100-52-7 Benzaldehyde Mice Female Gavage Forestomach Some Evidence SQUAMOUS CELL PAPILLOMA 0/50 5/50 6/50 Neoplastic Lesions
TR-378 100-52-7 Benzaldehyde Mice Male Gavage Forestomach Some Evidence SQUAMOUS CELL PAPILLOMA 1/50 2/50 5/50 Neoplastic Lesions
TR-383 81-49-2 1-Amino-2,4-dibromoanthraquinone Mice Female Dosed-Feed Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 2/50 16/50 27/50; SQUAMOUS CELL CARCINOMA 0/50 12/50 11/50 Neoplastic Lesions
TR-383 81-49-2 1-Amino-2,4-dibromoanthraquinone Mice Male Dosed-Feed Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 13/51 16/50; SQUAMOUS CELL CARCINOMA 0/50 12/51 13/50 Neoplastic Lesions
TR-384 96-18-4 1,2,3-Trichloropropane Mice Female Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 23/50 18/51 29/55; SQUAMOUS CELL CARCINOMA 0/50 46/50 49/51 49/55 Neoplastic Lesions
TR-342 62-73-7 Dichlorvos Mice Female Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 5/49 6/49 18/50 Neoplastic Lesions
TR-342 62-73-7 Dichlorvos Mice Male Gavage Forestomach Some Evidence SQUAMOUS CELL PAPILLOMA 1/50 1/50 5/50 Neoplastic Lesions
TR-370 271-89-6 Benzofuran Mice Female Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 2/50 8/50 5/50 OR SQUAMOUS CELL CARCINOMA 0/50 1/50 1/50 COMBINED 2/50 9/50 5/50 Neoplastic Lesions
TR-370 271-89-6 Benzofuran Mice Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 2/49 7/39 10/48 OR SQUAMOUS CELL CARCINOMA 0/49 4/39 3/48 COMBINED 2/49 11/39 13/48 Neoplastic Lesions
TR-400 96-13-9 2,3-Dibromo-1-propanol Mice Female Topical Application Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 12/49 17/50 OR SQUAMOUS CELL CARCINOMA 0/50 7/47 6/50 COMBINED 0/50 18/49 19/50 Neoplastic Lesions
TR-400 96-13-9 2,3-Dibromo-1-propanol Mice Male Topical Application Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 12/50 20/50 OR SQUAMOUS CELL CARCINOMA 0/50 2/50 1/49 COMBINED 0/50 14/50 21/49 Neoplastic Lesions
TR-400 96-13-9 2,3-Dibromo-1-propanol Rats Female Topical Application Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 1/50 3/50 23/50 Neoplastic Lesions
TR-400 96-13-9 2,3-Dibromo-1-propanol Rats Male Topical Application Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 1/50 17/50 Neoplastic Lesions
TR-408 7487-94-7 Mercuric chloride Rats Male Gavage Forestomach Some Evidence SQUAMOUS CELL PAPILLOMA 0/50 3/50 12/50 Neoplastic Lesions
TR-384 96-18-4 1,2,3-Trichloropropane Mice Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 3/52 28/51 22/54 33/56; SQUAMOUS CELL CARCINOMA 0/52 40/51 50/54 51/56 Neoplastic Lesions
TR-384 96-18-4 1,2,3-Trichloropropane Rats Female Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 13/49 32/51 17/52; SQUAMOUS CELL CARCINOMA 0/50 3/49 9/51 4/52 Neoplastic Lesions
TR-384 96-18-4 1,2,3-Trichloropropane Rats Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 29/50 33/49 38/52; SQUAMOUS CELL CARCINOMA 0/50 9/50 27/49 13/52 Neoplastic Lesions
TR-467 126-99-8 Chloroprene Mice Female Inhalation Forestomach Clear Evidence Squamous Cell Papilloma 0/50 0/50 0/50 4/50 Neoplastic Lesions
TR-467 126-99-8 Chloroprene Mice Male Inhalation Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 1/50 0/50 2/50 4/50 Neoplastic Lesions
TR-452 3296-90-0 2,2-bis(Bromomethyl)-1,3-propanediol Rats Male Dosed-Feed Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/51 0/53 0/51 1/55 5/60 Neoplastic Lesions
TR-434 106-99-0 1,3-Butadiene Mice Female Inhalation Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA OR CARCINOMA 0/50 0/50 3/50 2/50 4/50 22/80 Neoplastic Lesions
TR-434 106-99-0 1,3-Butadiene Mice Male Inhalation Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA OR CARCINOMA 1/50 0/50 0/50 1/50 8/50 4/73, STOP STUDY 3/50 7/50 9/50 10/50 Neoplastic Lesions
TR-484 111-76-2 2-Butoxyethanol (ethylene glycol monobutyl ether) Mice Female Inhalation Forestomach Some Evidence SQUAMOUS CELL PAPILLOMA 0/50 1/50 2/50 5/50 COMBINED 0/50 1/50 2/50 6/50 Neoplastic Lesions
TR-506 107-13-1 Acrylonitrile Mice Female Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 3/50 6/50 24/50 19/50 SQUAMOUS CELL CARCINOMA 0/50 1/50 1/50 11/50 COMBINED 3/50 7/50 25/50 29/50 Neoplastic Lesions
TR-506 107-13-1 Acrylonitrile Mice Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 3/50 4/50 19/50 25/50; SQUAMOUS CELL CARCINOMA 0/50 0/50 8/50 9/50 COMBINED 3/50 4/50 26/50 32/50 Neoplastic Lesions
TR-509 142-83-6 2,4-Hexadienal Mice Female Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 2/50 2/49 11/50 13/50 OR SQUAMOUS CELL CARCINOMA 0/50 0/49 0/50 7/50 COMBINED 2/50 2/49 11/50 18/50 Neoplastic Lesions
TR-509 142-83-6 2,4-Hexadienal Mice Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 2/50 4/50 5/50 8/50 OR SQUAMOUS CELL CARCINOMA 0/50 1/50 0/50 2/50 COMBINED 2/50 4/50 5/50 10/50 Neoplastic Lesions
TR-509 142-83-6 2,4-Hexadienal Rats Female Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 1/50 5/50 17/50 Neoplastic Lesions
TR-509 142-83-6 2,4-Hexadienal Rats Male Gavage Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 3/50 10/50 29/50 OR SQUAMOUS CELL CARCINOMA 0/50 0/50 1/50 2/50 COMBINED 0/50 3/50 11/50 29/50 Neoplastic Lesions
TR-510 51-79-6 Urethane Mice Male Dosed-Water Forestomach Clear Evidence SQUAMOUS CELL PAPILLOMA OR SQUAMOUS CELL CARCINOMA 0/46 2/47 3/44 5/45 Neoplastic Lesions
TR-558 14047-09-7 3,3',4,4'-Tetrachloroazobenzene Mice Female Gavage Forestomach Clear Evidence Squamous cell carcinoma 0/50 1/50 1/50 4/50 Neoplastic Lesions
TR-558 14047-09-7 3,3',4,4'-Tetrachloroazobenzene Mice Male Gavage Forestomach Clear Evidence Squamous cell carcinoma 0/50 1/50 1/49 3/50 Neoplastic Lesions
TR-558 14047-09-7 3,3',4,4'-Tetrachloroazobenzene Rats Female Gavage Forestomach Clear Evidence Squamous cell papilloma or carcinoma 0/50 1/50 0/50 4/50 Neoplastic Lesions
TR-544 3252-43-5 Water disinfection byproducts (Dibromoacetonitrile) Mice Female Dosed-Water Forestomach Clear Evidence Squamous cell papilloma 1/50 0/50 5/50 14/50 Neoplastic Lesions
TR-544 3252-43-5 Water disinfection byproducts (Dibromoacetonitrile) Mice Male Dosed-Water Forestomach Clear Evidence Squamous cell papilloma or carcinoma 0/50 1/50 0/50 5/50 Neoplastic Lesions
TR-550 1319-77-3 Cresols Mice Female Dosed-Feed Forestomach Some Evidence squamous cell papilloma (0/50, 1/50, 1/49, 10/50) Neoplastic Lesions
TR-588 5694-00-8 Glycidamide Mice Male Dosed-Water Forestomach Clear Evidence squamous cell papilloma 0/47 2/45 3/48 2/45 10/41 squamous cell carcinoma 0/47 0/45 0/48 0/45 2/41 squamous cell papilloma or carcinoma 0/47 2/45 3/48 2/45 12/41 Neoplastic Lesions
TR-588 5694-00-8 Glycidamide Mice Female Dosed-Water Forestomach Clear Evidence squamous cell papilloma 1/45 1/45 1/47 5/45 9/44 Neoplastic Lesions
TR-588 5694-00-8 Glycidamide Rats Female Dosed-Water Forestomach Clear Evidence squamous cell papilloma 0/48 1/48 0/48 0/47 3/46 Neoplastic Lesions
TR-575 79-06-1 Acrylamide Mice Female Dosed-Water Forestomach Clear Evidence squamous cell papilloma 4/46 0/46 2/48 5/45 8/42 Neoplastic Lesions
TR-575 79-06-1 Acrylamide Mice Male Dosed-Water Forestomach Clear Evidence squamous cell papilloma 0/46 2/45 2/46 6/47 6/44 squamous cell carcinoma 0/46 0/45 0/46 1/47 2/44 squamous cell papilloma or carcinoma 0/46 2/45 2/46 7/47 8/44 Neoplastic Lesions
TR-579 99-97-8 N,N-Dimethyl-p-toluidine Mice Female Gavage Forestomach Clear Evidence squamous cell papilloma 1/50, 5/50, 6/50, 7/50; squamous cell papilloma or carcinoma 1/50, 6/50, 6/50, 7/50 Neoplastic Lesions