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Organ Sites with Neoplasia

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  • Organ: Small intestine
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Publication No. CASRN Test Article Name Species Sex Route Organ Level of Evidence Tumor Type/Incidence Finding Type
TR-015 133-06-2 Captan Mice Female Dosed-Feed Intestines (Small) Positive (POLYPOID CARCINOMA) Neoplastic Lesions
TR-015 133-06-2 Captan Mice Male Dosed-Feed Intestines (Small) Positive (POLYPOID CARCINOMA) Neoplastic Lesions
TR-397 2429-74-5 C.I. Direct blue 15 Rats Female Dosed-Water Intestines (Small) Clear Evidence ADENOCARCINOMA 0/50 0/35 1/65 3/50 Neoplastic Lesions
TR-397 2429-74-5 C.I. Direct blue 15 Rats Male Dosed-Water Intestines (Small) Clear Evidence NEOPLASMS 0/50 1/35 0/65 2/50 Neoplastic Lesions
TR-405 6459-94-5 C.I. Acid red 114 Rats Female Dosed-Water Intestines (Small) Clear Evidence NEOPLASMS 0/50 0/35 1/65 2/50 Neoplastic Lesions
TR-452 3296-90-0 2,2-bis(Bromomethyl)-1,3-propanediol Rats Male Dosed-Feed Intestines (Small) Clear Evidence ADENOMA OR CARCINOMA 0/51 0/53 0/51 2/53 5/59 Neoplastic Lesions
TR-540 7220-79-3 Methylene blue trihydrate Mice Male Gavage Intestines (Small) Some Evidence CARCINOMA 0/50 1/50 2/50 4/50 ADENOMA OR CARCINOMA 1/50 2/50 4/50 6/50 Neoplastic Lesions
TR-546 7789-12-0 Sodium dichromate dihydrate (VI) Mice Female Dosed-Water Intestines (Small) Clear Evidence Duodenum: adenoma (0/50, 0/50, 2/50, 13/50, 12/50); carcinoma (0/50, 0/50, 0/50, 1/50, 6/50); Jejunum: adenoma (0/50, 1/50, 0/50, 2/50, 5/50); Duodenum, Jejunum, or Ileum: adenoma (0/50, 1/50, 2/50, 15/50, 16/50), carcinoma (1/50, 0/50, 2/50, 3/50, 7/50), adenoma or carcinoma (1/50, 1/50, 4/50, 17/50, 22/50) Neoplastic Lesions
TR-546 7789-12-0 Sodium dichromate dihydrate (VI) Mice Male Dosed-Water Intestines (Small) Clear Evidence Duodenum: adenoma (1/50, 0/50, 1/50, 5/50, 15/50); Duodenum, Jejunum, or Ileum: adenoma (1/50, 1/50, 1/50, 5/50, 17/50), carcinoma (0/50, 2/50, 1/50, 3/50, 5/50), adenoma or carcinoma (1/50, 3/50, 2/50, 7/50, 20/50) Neoplastic Lesions