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Organ Sites with Neoplasia

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  • Organ: Pituitary Gland
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Publication No. CASRN Test Article Name Species Sex Route Organ Level of Evidence Tumor Type/Incidence Finding Type
TR-235 17924-92-4 Zearalenone Mice Female Dosed-Feed Pituitary Gland Positive ADENOMA 3/46 2/43 13/42 Neoplastic Lesions
TR-235 17924-92-4 Zearalenone Mice Male Dosed-Feed Pituitary Gland Positive ADENOMA 0/40 4/45 6/44 Neoplastic Lesions
TR-332 149-30-4 2-Mercaptobenzothiazole Rats Female Gavage Pituitary Gland Some Evidence ADENOMA 15/49 24/50 25/50 Neoplastic Lesions
TR-340 5634-39-9 Iodinated glycerol Mice Female Gavage Pituitary Gland Some Evidence ADENOMA 10/47 15/45 24/46 Neoplastic Lesions
TR-388 96-45-7 Ethylene thiourea (ETU) Mice Female Dosed-Feed Pituitary Gland Clear Evidence ADENOMA 10/47 19/49 26/49; CARCINOMA 1/47 0/49 0/49 Neoplastic Lesions
TR-388 96-45-7 Ethylene thiourea (ETU) Mice Male Dosed-Feed Pituitary Gland Clear Evidence ADENOMA 0/44 0/42 8/41 Neoplastic Lesions
TR-589 32534-81-9 Pentabromodiphenyl Oxide (Technical) (DE 71) Rats Male Gavage Pituitary Gland Clear Evidence (pars distalis): adenoma 19/49 12/49 22/50 35/50 Neoplastic Lesions
TR-595 CELLPRADCDMA Cell Phone Radiation: CDMA Rats Male Whole Body Exposure Pituitary Gland Clear Evidence pars distalis, adenoma (17/89, 25/90, 34/90, 13/90) May Have Been Related
TR-595 CELLPRADGSM Cell Phone Radiation: GSM Rats Male Whole Body Exposure Pituitary Gland Clear Evidence pars distalis, adenoma (17/89, 28/90, 26/90, 26/90) May Have Been Related