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Organ Sites with Neoplasia

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  • Organ: Pancreas Acinar Cell
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Publication No. CASRN Test Article Name Species Sex Route Organ Level of Evidence Tumor Type/Incidence Finding Type
TR-026 1836-75-5 Nitrofen Rats Female Dosed-Feed Pancreas Acinar Cell Positive CARCINOMA Neoplastic Lesions
TR-251 26471-62-5 2,4- & 2,6-Toluene diisocyanate Rats Male Gavage Pancreas Acinar Cell Positive ADENOMA 1/47 3/47 7/49 Neoplastic Lesions
TR-196 87-29-6 Cinnamyl anthranilate Rats Male Dosed-Feed Pancreas Acinar Cell Positive ADENOMA OR CARCINOMA Neoplastic Lesions
TR-304 115-28-6 Chlorendic acid Rats Male Dosed-Feed Pancreas Acinar Cell Clear Evidence ADENOMA 0/49 4/50 6/50 Neoplastic Lesions
TR-332 149-30-4 2-Mercaptobenzothiazole Rats Male Gavage Pancreas Acinar Cell Some Evidence ADENOMA 2/50 13/50 6/50 Neoplastic Lesions
TR-334 121-88-0 2-Amino-5-nitrophenol Rats Male Gavage Pancreas Acinar Cell Some Evidence ADENOMA 1/50 10/50 3/49 Neoplastic Lesions
TR-342 62-73-7 Dichlorvos Rats Male Gavage Pancreas Acinar Cell Some Evidence ADENOMA 25/50 30/49 33/50 Neoplastic Lesions
TR-384 96-18-4 1,2,3-Trichloropropane Rats Male Gavage Pancreas Acinar Cell Clear Evidence ADENOMA 5/50 21/50 36/49 29/52 Neoplastic Lesions
TR-458 85-68-7 Butyl benzyl phthalate Rats Male Dosed-Feed Pancreas Acinar Cell Some Evidence ADENOMA 3/50 2/49 3/50 10/50 OR CARCINOMA 0/50 0/49 0/50 1/50 COMBINED 3/50 2/49 3/50 11/50 Neoplastic Lesions
TR-530 TEFBINARYMIX TEF evaluation (Binary mixture; PCB 126/PCB 153) Rats Female Gavage Pancreas Acinar Cell Clear Evidence ADENOMA 0/53 1/53 1/52 3/52 1/50 ADENOMA OR CARCINOMA 0/53 1/53 1/52 4 /52 2/50 Neoplastic Lesions