COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

Search Results

One moment please while the data are loaded...
View results
  • Organ: Mammary Gland
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Displays results that match exactly with the given criteria.
Exact Match Publication No. CASRN Test Article Name Species Sex Route Organ Level of Evidence Tumor Type/Incidence Finding Type
Yes TR-019 366-70-1 Procarbazine hydrochloride Rats Female Intraperitoneal Injection Mammary Gland Positive (ADENOCARCINOMA) Neoplastic Lesions
Yes TR-019 366-70-1 Procarbazine hydrochloride Rats Male Intraperitoneal Injection Mammary Gland Positive (ADENOCARCINOMA) Neoplastic Lesions
Yes TR-028 96-12-8 1,2-Dibromo-3-chloropropane Rats Female Gavage Mammary Gland Positive (ADENOCARCINOMA) Neoplastic Lesions
Yes TR-032 3778-73-2 Isophosphamide Rats Female Intraperitoneal Injection Mammary Gland Positive (FIBROADENOMA) Neoplastic Lesions
Yes TR-092 122-66-7 Hydrazobenzene Rats Female Dosed-Feed Mammary Gland Positive (ADENOCARCINOMA) Neoplastic Lesions
Yes TR-049 7008-42-6 Acronycine Rats Female Intraperitoneal Injection Mammary Gland Positive (ADENOCARCINOMA) Neoplastic Lesions
Yes TR-054 121-14-2 2,4-Dinitrotoluene Rats Female Dosed-Feed Mammary Gland Positive (FIBROADENOMA) Neoplastic Lesions
Yes TR-055 107-06-2 1,2-Dichloroethane Mice Female Gavage Mammary Gland Positive (ADENOCARCINOMA) Neoplastic Lesions
Yes TR-055 107-06-2 1,2-Dichloroethane Rats Female Gavage Mammary Gland Positive (ADENOCARCINOMA) Neoplastic Lesions
Yes TR-060 3546-10-9 Phenesterin Rats Female Gavage Mammary Gland Positive (ADENOCARCINOMA) Neoplastic Lesions
Yes TR-115 95-06-7 Sulfallate Mice Female Dosed-Feed Mammary Gland Positive (ADENOCARCINOMA) Neoplastic Lesions
Yes TR-115 95-06-7 Sulfallate Rats Female Dosed-Feed Mammary Gland Positive (ADENOCARCINOMA) Neoplastic Lesions
Yes TR-118 602-87-9 5-Nitroacenaphthene Rats Female Dosed-Feed Mammary Gland Positive (ADENOCARCINOMA) Neoplastic Lesions
Yes TR-146 139-94-6 Nithiazide Rats Female Dosed-Feed Mammary Gland Positive (FIBROADENOMA OR CYSTADENOMA) Neoplastic Lesions
Yes TR-153 636-21-5 o-Toluidine hydrochloride Rats Female Dosed-Feed Mammary Gland Positive (ADENOMA OR FIBROADENOMA) Neoplastic Lesions
Yes TR-162 95-80-7 2,4-Diaminotoluene (2,4-toluene diamine) Rats Female Dosed-Feed Mammary Gland Positive (ADENOMA, CARCINOMA) Neoplastic Lesions
Yes TR-207 21739-91-3 Cytembena Rats Female Intraperitoneal Injection Mammary Gland Positive FIBROADENOMA 13/49 22/50 36/50 Neoplastic Lesions
Yes TR-210 106-93-4 1,2-Dibromoethane Mice Female Inhalation Mammary Gland Positive ADENOCARCINOMA 2/50 14/50 8/50 Neoplastic Lesions
Yes TR-210 106-93-4 1,2-Dibromoethane Rats Female Inhalation Mammary Gland Positive FIBROADENOMA 4/50 29/50 24/50 Neoplastic Lesions
Yes TR-251 26471-62-5 2,4- & 2,6-Toluene diisocyanate Rats Female Gavage Mammary Gland Positive FIBROADENOMA 15/50 21/50 18/50 Neoplastic Lesions
Yes TR-193 50-55-5 Reserpine Mice Female Dosed-Feed Mammary Gland Positive (FIBROADENOMA, ADENOCARCINOMA, ADENOSQUAMOUS CARCINOMA) Neoplastic Lesions
Yes TR-288 106-99-0 1,3-Butadiene Mice Female Inhalation Mammary Gland Clear Evidence ACINAR CELL CARCINOMA 0/50 2/49 6/49 Neoplastic Lesions
Yes TR-289 71-43-2 Benzene Mice Female Gavage Mammary Gland Clear Evidence CARCINOMA 0/49 2/45 5/50 10/49; CARCINOSARCOMA 0/49 0/45 1/50 4/49 Neoplastic Lesions
Yes TR-306 75-09-2 Methylene chloride Rats Female Inhalation Mammary Gland Clear Evidence ADENOMA 0/50 0/50 0/50 1/50 OR FIBROADENOMA 5/50 11/50 13/50 22/50 COMBINED 5/50 11/50 13/50 23/50 Neoplastic Lesions
Yes TR-306 75-09-2 Methylene chloride Rats Male Inhalation Mammary Gland Some Evidence ADENOMA 0/50 0/50 0/50 1/50 OR FIBROADENOMA 0/50 0/50 2/50 4/50 COMBINED 0/50 0/50 2/50 5/50 Neoplastic Lesions
Yes TR-326 75-21-8 Ethylene oxide Mice Female Inhalation Mammary Gland Clear Evidence ADENOCARCINOMA 1/49 6/48 4/49; ADENOSQUAMOUS CARCINOMA 0/49 2/48 2/49 Neoplastic Lesions
Yes TR-374 556-52-5 Glycidol Mice Female Gavage Mammary Gland Clear Evidence ADENOMA 0/50 1/50 0/50, FIBROADENOMA 1/50 0/50 0/50, OR ADENOCARCINOMA 1/50 5/50 15/50 COMBINED 2/50 6/50 15/50 Neoplastic Lesions
Yes TR-374 556-52-5 Glycidol Rats Female Gavage Mammary Gland Clear Evidence FIBROADENOMA 14/50 32/50 29/50; ADENOCARCINOMA 1/50 11/50 16/50 Neoplastic Lesions
Yes TR-374 556-52-5 Glycidol Rats Male Gavage Mammary Gland Clear Evidence FIBROADENOMA 3/50 8/50 7/50 Neoplastic Lesions
Yes TR-337 59-87-0 Nitrofurazone Rats Female Dosed-Feed Mammary Gland Clear Evidence FIBROADENOMA 8/49 36/50 36/50 Neoplastic Lesions
Yes TR-356 54-31-9 Furosemide Mice Female Dosed-Feed Mammary Gland Some Evidence ADENOCARCINOMA 0/50 2/50 5/48 Neoplastic Lesions
Yes TR-358 303-47-9 Ochratoxin A Rats Female Gavage Mammary Gland Clear Evidence FIBROADENOMA 17/50 23/51 22/50 28/50 Neoplastic Lesions
Yes TR-372 20325-40-0 3,3'-Dimethoxybenzidine dihydrochloride Rats Female Dosed-Water Mammary Gland Clear Evidence ADENOCARCINOMA 1/60 2/45 14/75 20/60 Neoplastic Lesions
Yes TR-390 612-82-8 3,3'-Dimethylbenzidine dihydrochloride Rats Female Dosed-Water Mammary Gland Clear Evidence ADENOCARCINOMA 0/60 1/45 3/75 6/60 Neoplastic Lesions
Yes TR-400 96-13-9 2,3-Dibromo-1-propanol Rats Female Topical Application Mammary Gland Clear Evidence ADENOCARCINOMA 0/50 0/50 5/50 Neoplastic Lesions
Yes TR-384 96-18-4 1,2,3-Trichloropropane Rats Female Gavage Mammary Gland Clear Evidence ADENOCARCINOMA 1/50 6/49 12/52 21/52 Neoplastic Lesions
Yes TR-467 126-99-8 Chloroprene Mice Female Inhalation Mammary Gland Clear Evidence CARCINOMA 3/50 4/50 7/50 12/50 Neoplastic Lesions
Yes TR-467 126-99-8 Chloroprene Rats Female Inhalation Mammary Gland Clear Evidence FIBROADENOMA 24/49 32/50 36/50 36/50 Neoplastic Lesions
Yes TR-452 3296-90-0 2,2-bis(Bromomethyl)-1,3-propanediol Rats Male Dosed-Feed Mammary Gland Clear Evidence FIBROADENOMA 0/51 4/53 6/51 6/55 5/60 OR ADENOMA 0/51 0/53 1/51 1/55 0/60 COMBINED 0/51 4/53 7/51 7/55 5/60 Neoplastic Lesions
Yes TR-461 75-52-5 Nitromethane Rats Female Inhalation Mammary Gland Clear Evidence FIBROADENOMA 19/50 21/50 33/50 36/50 OR CARCINOMA 2/50 7/50 1/50 11/50 COMBINED 9/50 25/50 34/50 39/50 Neoplastic Lesions
Yes TR-434 106-99-0 1,3-Butadiene Mice Female Inhalation Mammary Gland Clear Evidence ADENOACANTHOMA, ADENOCARCINOMA, OR MALIGNANT MIXED TUMOR 0/50 2/50 4/50 12/50 15/50 16/80 Neoplastic Lesions
Yes TR-486 78-79-5 Isoprene Rats Female Inhalation Mammary Gland Some Evidence FIBROADENOMA 19/50 35/50 32/50 32/50 MULTIPLE FIBROADENOMA 7/50 12/50 19/50 17/50 Neoplastic Lesions
Yes TR-452 3296-90-0 2,2-bis(Bromomethyl)-1,3-propanediol Rats Female Dosed-Feed Mammary Gland Clear Evidence FIBROADENOMA 25/50 45/51 46/53 45/52 Neoplastic Lesions
Yes TR-486 78-79-5 Isoprene Rats Male Inhalation Mammary Gland Clear Evidence FIBROADENOMA 2/50 4/50 6/50 21/50 FIBROADENOMA OR CARCINOMA COMBINED 2/50 5/50 7/50 21/50 Neoplastic Lesions
Yes TR-491 93-15-2 Methyleugenol Rats Male Gavage Mammary Gland Clear Evidence FIBROADENOMA 5/50 5/50 15/50 13/50 6/50 Neoplastic Lesions
Yes TR-504 88-72-2 o-Nitrotoluene Rats Female Dosed-Feed Mammary Gland Clear Evidence FIBROADENOMA 23/60 47/60 52/60 56/60 Neoplastic Lesions
Yes TR-504 88-72-2 o-Nitrotoluene Rats Male Dosed-Feed Mammary Gland Clear Evidence FIBROADENOMA 0/60 7/60 10/60 2/60 13/60 20/60 Neoplastic Lesions
Yes TR-510 51-79-6 Urethane Mice Female Dosed-Water Mammary Gland Clear Evidence ADENOACANTHOMA 0/47 1/46 1/46 11/48 ADENOCARCINOMA 4/47 3/46 3/46 11/48 COMBINED 4/47 4/46 4/46 22/48 Neoplastic Lesions
Yes TR-549 5589-96-8 Water disinfection byproducts (Bromochloroacetic acid) Rats Female Dosed-Water Mammary Gland Clear Evidence Fibroadenoma, multiple 22/50 24/50 43/50 38/50 Neoplastic Lesions
Yes TR-588 5694-00-8 Glycidamide Rats Female Dosed-Water Mammary Gland Clear Evidence fibroadenoma 16/48 26/48 35/48 33/48 36/48 Neoplastic Lesions
Yes TR-588 5694-00-8 Glycidamide Mice Female Dosed-Water Mammary Gland Clear Evidence adenoacanthoma 0/45 0/48 0/47 1/47 8/45 adenocarcinoma 1/45 1/48 2/47 9/47 11/45 adenoacanthoma or adenocarcinoma 1/45 1/48 2/47 9/47 18/45 Neoplastic Lesions
Yes TR-575 79-06-1 Acrylamide Mice Female Dosed-Water Mammary Gland Clear Evidence adenoacanthoma 0/47 1/46 1/48 2/45 4/42 adenocarcinoma 0/47 4/46 6/48 2/45 13/42 adenoacanthoma or adenocarcinoma 0/47 4/46 7/48 4/45 17/42 Neoplastic Lesions
Yes TR-575 79-06-1 Acrylamide Rats Female Dosed-Water Mammary Gland Clear Evidence fibroadenoma 16/48 18/48 24/46 22/47 31/48 Neoplastic Lesions