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Organ Sites with Neoplasia

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  • Organ: Kidney Transitional Cell
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Publication No. CASRN Test Article Name Species Sex Route Organ Level of Evidence Tumor Type/Incidence Finding Type
TR-006 18662-53-8 Nitrilotriacetic acid trisodium monohydrate Rats Male Dosed-Feed Kidney Transitional Cell Positive CARCINOMA Neoplastic Lesions
TR-089 134-29-2 o-Anisidine hydrochloride Rats Male Dosed-Feed Kidney Transitional Cell Positive CARCINOMA Neoplastic Lesions
TR-313 2385-85-5 Mirex Rats Male Dosed-Feed Kidney Transitional Cell Clear Evidence PAPILLOMA 0/51 0/51 0/52 0/52 1/51 3/52 Neoplastic Lesions
TR-323 756-79-6 Dimethyl methylphosphonate Rats Male Gavage Kidney Transitional Cell Some Evidence PAPILLOMA 0/50 7/50 3/49 Neoplastic Lesions
TR-335 6373-74-6 C.I. Acid orange 3 Rats Female Gavage Kidney Transitional Cell Clear Evidence CARCINOMA 0/50 0/50 6/50 Neoplastic Lesions
TR-367 50-33-9 Phenylbutazone Rats Female Gavage Kidney Transitional Cell Some Evidence CARCINOMA 0/50 0/50 2/50 Neoplastic Lesions
TR-416 91-23-6 o-Nitroanisole Rats Female Dosed-Feed Kidney Transitional Cell Clear Evidence (STOP STUDY) PAPILLOMA 0/60 0/60 1/60 OR CARCINOMA 0/60 0/60 1/60 Neoplastic Lesions
TR-457 599-79-1 Salicylazosulfapyridine Rats Female Gavage Kidney Transitional Cell Some Evidence PAPILLOMA 0/50 0/50 0/50 2/50 Neoplastic Lesions
TR-457 599-79-1 Salicylazosulfapyridine Rats Female Gavage Kidney Transitional Cell Some Evidence PAPILLOMA 0/50 0/50 0/50 2/50 Neoplastic Lesions
TR-416 91-23-6 o-Nitroanisole Rats Male Dosed-Feed Kidney Transitional Cell Clear Evidence PAPILLOMA (STOP STUDY) 0/60 0/60 4/60 OR CARCINOMA 0/60 1/60 8/60 Neoplastic Lesions
TR-494 84-65-1 Anthraquinone Rats Male Dosed-Feed Kidney Transitional Cell Some Evidence PAPILLOMA 0/50 0/50 2/50 0/50 1/50 Neoplastic Lesions