COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

Search Results

One moment please while the data are loaded...
View results
  • Organ: Hematopoietic System
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Displays results that match exactly with the given criteria.
Exact Match Publication No. CASRN Test Article Name Species Sex Route Organ Level of Evidence Tumor Type/Incidence Finding Type
Yes TR-019 366-70-1 Procarbazine hydrochloride Mice Female Intraperitoneal Injection Hematopoietic System Positive (LYMPHOMA OR LEUKEMIA) Neoplastic Lesions
Yes TR-019 366-70-1 Procarbazine hydrochloride Mice Male Intraperitoneal Injection Hematopoietic System Positive (LYMPHOMA OR LEUKEMIA) Neoplastic Lesions
Yes TR-019 366-70-1 Procarbazine hydrochloride Rats Female Intraperitoneal Injection Hematopoietic System Positive (LYMPHOMA) Neoplastic Lesions
Yes TR-019 366-70-1 Procarbazine hydrochloride Rats Male Intraperitoneal Injection Hematopoietic System Positive (LYMPHOMA OR LEUKEMIA) Neoplastic Lesions
Yes TR-032 3778-73-2 Isophosphamide Mice Female Intraperitoneal Injection Hematopoietic System Positive (LYMPHOMA) Neoplastic Lesions
Yes TR-039 303-34-4 Lasiocarpine Rats Female Dosed-Feed Hematopoietic System Positive Lymphoma/Leukemia Neoplastic Lesions
Yes TR-042 320-67-2 5-Azacytidine Mice Female Intraperitoneal Injection Hematopoietic System Positive (LYMPHOMA OR GRANULOCYTIC SARCOMA) Neoplastic Lesions
Yes TR-053 121-66-4 2-Amino-5-nitrothiazole Rats Male Dosed-Feed Hematopoietic System Positive (LYMPHOMA, LEUKEMIA) Neoplastic Lesions
Yes TR-058 52-24-4 tris(Aziridinyl)-phosphine sulfide (thio-tepa) Mice Female Intraperitoneal Injection Hematopoietic System Positive (LYMPHOMA, LEUKEMIA) Neoplastic Lesions
Yes TR-058 52-24-4 tris(Aziridinyl)-phosphine sulfide (thio-tepa) Mice Male Intraperitoneal Injection Hematopoietic System Positive (LYMPHOMA, LEUKEMIA) Neoplastic Lesions
Yes TR-058 52-24-4 tris(Aziridinyl)-phosphine sulfide (thio-tepa) Rats Male Intraperitoneal Injection Hematopoietic System Positive (LYMPHOMA OR LEUKEMIA) Neoplastic Lesions
Yes TR-059 22966-79-6 Estradiol mustard Mice Female Gavage Hematopoietic System Positive (LYMPHOMA) Neoplastic Lesions
Yes TR-059 22966-79-6 Estradiol mustard Mice Male Gavage Hematopoietic System Positive (LYMPHOMA OR LEUKEMIA) Neoplastic Lesions
Yes TR-060 3546-10-9 Phenesterin Mice Female Gavage Hematopoietic System Positive (LYMPHOMA) Neoplastic Lesions
Yes TR-060 3546-10-9 Phenesterin Mice Male Gavage Hematopoietic System Positive (LYMPHOMA) Neoplastic Lesions
Yes TR-078 21416-87-5 ICRF-159 Mice Female Intraperitoneal Injection Hematopoietic System Positive (LYMPHOMA) Neoplastic Lesions
Yes TR-128 91-93-0 3,3'-Dimethoxybenzidine-4,4'-diisocyanate Rats Female Dosed-Feed Hematopoietic System Positive (LYMPHOMA OR LEUKEMIA) Neoplastic Lesions
Yes TR-128 91-93-0 3,3'-Dimethoxybenzidine-4,4'-diisocyanate Rats Male Dosed-Feed Hematopoietic System Positive (LYMPHOMA OR LEUKEMIA) Neoplastic Lesions
Yes TR-134 128-66-5 C.I. Vat yellow 4 Mice Male Dosed-Feed Hematopoietic System Positive (LYMPHOMA) Neoplastic Lesions
Yes TR-144 117-79-3 2-Aminoanthraquinone Mice Female Dosed-Feed Hematopoietic System Positive (LYMPHOMA) Neoplastic Lesions
Yes TR-155 88-06-2 2,4,6-Trichlorophenol Rats Male Dosed-Feed Hematopoietic System Positive (LEUKEMIA) Neoplastic Lesions
Yes TR-213 85-68-7 Butyl benzyl phthalate Rats Female Dosed-Feed Hematopoietic System Positive LEUKEMIA 7/49 7/49 18/50 Neoplastic Lesions
Yes TR-248 13552-44-8 4,4'-Methylenedianiline dihydrochloride Mice Female Dosed-Water Hematopoietic System Positive LYMPHOMA 13/50 28/50 29/50 Neoplastic Lesions
Yes TR-253 2835-39-4 Allyl isovalerate Mice Female Gavage Hematopoietic System Positive LYMPHOMA 11/50 11/50 18/50 Neoplastic Lesions
Yes TR-253 2835-39-4 Allyl isovalerate Rats Male Gavage Hematopoietic System Positive LEUKEMIA 1/50 4/50 7/50 Neoplastic Lesions
Yes TR-288 106-99-0 1,3-Butadiene Mice Female Inhalation Hematopoietic System Clear Evidence LYMPHOMA 1/50 10/49 10/49 Neoplastic Lesions
Yes TR-288 106-99-0 1,3-Butadiene Mice Male Inhalation Hematopoietic System Clear Evidence LYMPHOMA 0/50 23/50 29/50 Neoplastic Lesions
Yes TR-289 71-43-2 Benzene Mice Female Gavage Hematopoietic System Clear Evidence LYMPHOMA 15/49 25/45 26/50 22/49 Neoplastic Lesions
Yes TR-289 71-43-2 Benzene Mice Male Gavage Hematopoietic System Clear Evidence LYMPHOMA 4/49 10/48 10/50 15/49 Neoplastic Lesions
Yes TR-298 597-25-1 Dimethyl morpholinophosphoramidate Rats Female Gavage Hematopoietic System Some Evidence LEUKEMIA 9/50 13/50 12/49 18/50 Neoplastic Lesions
Yes TR-298 597-25-1 Dimethyl morpholinophosphoramidate Rats Male Gavage Hematopoietic System Some Evidence LEUKEMIA 14/50 21/50 19/50 25/50 Neoplastic Lesions
Yes TR-305 108171-27-3 Chlorinated paraffins: C23, 43% chlorine Mice Male Gavage Hematopoietic System Clear Evidence LYMPHOMA 6/50 12/50 16/50 Neoplastic Lesions
Yes TR-326 75-21-8 Ethylene oxide Mice Female Inhalation Hematopoietic System Clear Evidence LYMPHOMA 9/49 6/48 22/49 Neoplastic Lesions
Yes TR-332 149-30-4 2-Mercaptobenzothiazole Rats Male Gavage Hematopoietic System Some Evidence LEUKEMIA 7/50 16/50 3/50 Neoplastic Lesions
Yes TR-311 127-18-4 Tetrachloroethylene Rats Female Inhalation Hematopoietic System Some Evidence LEUKEMIA 18/50 30/50 29/50 Neoplastic Lesions
Yes TR-311 127-18-4 Tetrachloroethylene Rats Male Inhalation Hematopoietic System Clear Evidence LEUKEMIA 28/50 37/50 37/50 Neoplastic Lesions
Yes TR-313 2385-85-5 Mirex Rats Female Dosed-Feed Hematopoietic System Clear Evidence LEUKEMIA 6/52 9/52 14/52 Neoplastic Lesions
Yes TR-374 556-52-5 Glycidol Rats Female Gavage Hematopoietic System Clear Evidence LEUKEMIA 13/50 14/50 20/50 Neoplastic Lesions
Yes TR-340 5634-39-9 Iodinated glycerol Rats Male Gavage Hematopoietic System Some Evidence LEUKEMIA 14/50 29/50 24/50 Neoplastic Lesions
Yes TR-342 62-73-7 Dichlorvos Rats Male Gavage Hematopoietic System Some Evidence LEUKEMIA 11/50 20/50 21/50 Neoplastic Lesions
Yes TR-366 123-31-9 Hydroquinone Rats Female Gavage Hematopoietic System Some Evidence Leukemia 9/55 15/55 22/55 Neoplastic Lesions
Yes TR-397 2429-74-5 C.I. Direct blue 15 Rats Female Dosed-Water Hematopoietic System Clear Evidence MONONUCLEAR CELL LEUKEMIA 7/50 13/35 27/65 15/50 Neoplastic Lesions
Yes TR-402 110-00-9 Furan Rats Female Gavage Hematopoietic System Clear Evidence MONONUCLEAR CELL LEUKEMIA 8/50 9/50 17/50 21/50 Neoplastic Lesions
Yes TR-402 110-00-9 Furan Rats Male Gavage Hematopoietic System Clear Evidence MONONUCLEAR CELL LEUKEMIA 8/50 11/50 17/50 25/50 Neoplastic Lesions
Yes TR-452 3296-90-0 2,2-bis(Bromomethyl)-1,3-propanediol Rats Male Dosed-Feed Hematopoietic System Clear Evidence MONONUCLEAR CELL LEUKEMIA 27/51 29/53 40/51 34/55 25/60 Neoplastic Lesions
Yes TR-465 77-09-8 Phenolphthalein Mice Female Dosed-Feed Hematopoietic System Clear Evidence HISTIOCYTIC SARCOMA 0/50 2/50 7/50 7/50; LYMPHOMA 15/50 28/50 33/5 25/50; LYMPHOMA (THYMIC ORIGIN) 1/50 9/50 10/50 7/50 Neoplastic Lesions
Yes TR-465 77-09-8 Phenolphthalein Mice Male Dosed-Feed Hematopoietic System Clear Evidence HISTIOCYTIC SARCOMA 1/50 3/50 11/50 12/49; LYMPHOMA (THYMIC ORIGIN) 0/50 4/50 7/50 2/49 Neoplastic Lesions
Yes TR-416 91-23-6 o-Nitroanisole Rats Female Dosed-Feed Hematopoietic System Clear Evidence MONONUCLEAR CELL LEUKEMIA 14/50 11/50 14/50 26/50 Neoplastic Lesions
Yes TR-416 91-23-6 o-Nitroanisole Rats Male Dosed-Feed Hematopoietic System Clear Evidence MONONUCLEAR CELL LEUKEMIA 26/50 25/50 42/50 34/50 Neoplastic Lesions
Yes TR-434 106-99-0 1,3-Butadiene Mice Female Inhalation Hematopoietic System Clear Evidence LYMPHOMA 6/50 12/50 11/50 7/50 9/50 32/80; HISTIOCYTIC SARCOMA 3/50 2/50 7/50 4/50 7/50 4/80 Neoplastic Lesions
Yes TR-434 106-99-0 1,3-Butadiene Mice Male Inhalation Hematopoietic System Clear Evidence LYMPHOMA 4/50 2/50 4/50 6/50 2/50 51/73, STOP STUDY 8/50 22/50 8/50 33/50; HISTIOCYTIC SARCOMA 0/50 0/50 4/50 5/50 7/50 4/73, STOP STUDY 5/50 2/50 7/50 2/50 Neoplastic Lesions
Yes TR-450 116-14-3 Tetrafluoroethylene Mice Female Inhalation Hematopoietic System Clear Evidence HISTIOCYTIC SARCOMA 1/48 21/48 19/47 18/48 Neoplastic Lesions
Yes TR-450 116-14-3 Tetrafluoroethylene Mice Male Inhalation Hematopoietic System Clear Evidence HISTIOCYTIC SARCOMA 0/48 12/48 7/48 7/48 Neoplastic Lesions
Yes TR-450 116-14-3 Tetrafluoroethylene Rats Female Inhalation Hematopoietic System Clear Evidence MONONUCLEAR CELL LEUKEMIA: 16/50 31/50 23/50 36/50 Neoplastic Lesions
Yes TR-492 1303-00-0 Gallium arsenide Rats Female Inhalation Hematopoietic System Clear Evidence MONONUCLEAR CELL LEUKEMIA 22/50 21/50 18/50 33/50 Neoplastic Lesions
Yes TR-504 88-72-2 o-Nitrotoluene Mice Female Dosed-Feed Hematopoietic System Clear Evidence HEMANGIOSARCOMA 0/60 2/60 3/60 50/60 Neoplastic Lesions
Yes TR-504 88-72-2 o-Nitrotoluene Mice Male Dosed-Feed Hematopoietic System Clear Evidence HEMANGIOSARCOMA 4/60 17/60 55/60 60/60 Neoplastic Lesions
Yes TR-508 23246-96-0 Riddelliine Rats Female Gavage Hematopoietic System Clear Evidence MONONUCLEAR CELL LEUKEMIA (ALL ORGANS) 12/50 8/50 13/50 18/50 18/50 14/50 Neoplastic Lesions
Yes TR-508 23246-96-0 Riddelliine Rats Male Gavage Hematopoietic System Clear Evidence Hematopoietic System: MONONUCLEAR CELL LEUKEMIA (ALL ORGANS) 2/50 9/50 Neoplastic Lesions
Yes TR-533 119-61-9 Benzophenone Mice Female Dosed-Feed Hematopoietic System Some Evidence HISTIOCYTIC SARCOMA: 0/50 0/50 5/50 3/50 Neoplastic Lesions
Yes TR-537 631-64-1 Water disinfection byproducts (Dibromoacetic acid) Rats Female Dosed-Water Hematopoietic System Some Evidence MONONUCLEAR CELL LEUKEMIA (ALL ORGANS) 11/50 13/50 16/50 22/50 Neoplastic Lesions
Yes TR-537 631-64-1 Water disinfection byproducts (Dibromoacetic acid) Rats Male Dosed-Water Hematopoietic System Some Evidence MALIGNANT MESOTHELIOMA (ALL ORGANS) 3/50 1/50 0/50 10/50 Neoplastic Lesions