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Organ Sites with Neoplasia

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  • Organ: Esophagus
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Publication No. CASRN Test Article Name Species Sex Route Organ Level of Evidence Tumor Type/Incidence Finding Type
TR-316 513-37-1 Dimethylvinyl chloride (DMVC) Rats Female Gavage Esophagus Clear Evidence SQUAMOUS CELL CARCINOMA 0/49 3/50 1/49 Neoplastic Lesions
TR-316 513-37-1 Dimethylvinyl chloride (DMVC) Rats Male Gavage Esophagus Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 2/50 3/49 OR SQUAMOUS CELL CARCINOMA 0/50 4/50 1/49 COMBINED 0/50 6/50 4/49 Neoplastic Lesions
TR-400 96-13-9 2,3-Dibromo-1-propanol Rats Female Topical Application Esophagus Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 9/50 38/50 Neoplastic Lesions
TR-400 96-13-9 2,3-Dibromo-1-propanol Rats Male Topical Application Esophagus Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 19/50 33/50 Neoplastic Lesions
TR-452 3296-90-0 2,2-bis(Bromomethyl)-1,3-propanediol Rats Male Dosed-Feed Esophagus Clear Evidence SQUAMOUS CELL PAPILLOMA 0/51 0/53 1/51 5/55 0/60 Neoplastic Lesions
TR-452 3296-90-0 2,2-bis(Bromomethyl)-1,3-propanediol Rats Female Dosed-Feed Esophagus Clear Evidence SQUAMOUS CELL PAPILLOMA 0/50 0/51 1/53 10/52 Neoplastic Lesions