CIMSTAR 3800 (CIMSTAR3800)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View Equivocal Evidence, Female, Rats Equivocal Evidence, Male, Rats

An overview of chronic evidence from Mice studies.
Mice
View No Evidence, Male, Mice Some Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to CIMSTAR 3800 (CIMSTAR3800).
Micronucleus - Rats
View Male: Negative Female: Negative

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to CIMSTAR 3800 (CIMSTAR3800).
Micronucleus - Mice
View Male: Negative Female: Negative

An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to CIMSTAR 3800 (CIMSTAR3800).
Bacterial Mutagenicity
View Weakly Positive

Citation Information

NTP. CIMSTAR 3800 (CIMSTAR3800). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

TR-586 Toxicology and Carcinogenesis Studies of CIMSTAR® 3800 (CASRN CIMSTAR3800) in Wistar Han Rats and B6C3F1 Mice (Inhalation Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Data

3-Month Evaluation of the Toxicity (C20515) of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in F344/NTac Rats via Whole Body Respiratory Exposure

Study Tables

E03 - Growth Curves (83 kB)
E04 - Mean Body Weights and Survival Table (15 kB)
E05 - Clinical Observations Summary (21 kB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (24 kB)
P04 - Neoplasms by Individual Animal (123 kB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (23 kB)
P09 - Non-Neoplastic Lesions by Individual Animal (151 kB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (85 kB)
P14 - Individual Animal Pathology Data (284 kB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (25 kB)
P40 - Survival Curves (76 kB)

Individual Animal Data

Female Individual Animal Body Weight Data (37 kB)
Female Individual Animal Clinical Observations (31 kB)
Female Individual Animal Non Neoplastic Pathology Data (164 kB)
Female Individual Animal Organ Weight Data (19 kB)
Female Individual Animal Survival Data (11 kB)
Male Individual Animal Body Weight Data (37 kB)
Male Individual Animal Clinical Observations (23 kB)
Male Individual Animal Non Neoplastic Pathology Data (168 kB)
Male Individual Animal Organ Weight Data (19 kB)
Male Individual Animal Survival Data (11 kB)

Data

3-Month Evaluation of the Toxicity (C20515) of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in B6C3F1 Mice via Whole Body Respiratory Exposure

Study Tables

E03 - Growth Curves (87 kB)
E04 - Mean Body Weights and Survival Table (15 kB)
E05 - Clinical Observations Summary (21 kB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (23 kB)
P04 - Neoplasms by Individual Animal (119 kB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (23 kB)
P09 - Non-Neoplastic Lesions by Individual Animal (142 kB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (64 kB)
P14 - Individual Animal Pathology Data (274 kB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (24 kB)
P40 - Survival Curves (76 kB)

Individual Animal Data

Female Individual Animal Body Weight Data (36 kB)
Female Individual Animal Clinical Observations (17 kB)
Female Individual Animal Non Neoplastic Pathology Data (95 kB)
Female Individual Animal Organ Weight Data (19 kB)
Female Individual Animal Survival Data (11 kB)
Male Individual Animal Body Weight Data (36 kB)
Male Individual Animal Clinical Observations (39 kB)
Male Individual Animal Non Neoplastic Pathology Data (91 kB)
Male Individual Animal Organ Weight Data (19 kB)
Male Individual Animal Survival Data (11 kB)

Data

Evaluation of the Chronic Toxicity and Carcinogenicity (C20515) of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in Wistar Han Rats via Whole Body Respiratory Exposure

Study Tables

E03 - Growth Curves (67 kB)
E04 - Mean Body Weights and Survival Table (24 kB)
E05 - Clinical Observations Summary (25 kB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (52 kB)
P04 - Neoplasms by Individual Animal (665 kB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (48 kB)
P08 - Statistical Analysis of Primary Tumors (284 kB)
P09 - Non-Neoplastic Lesions by Individual Animal (784 kB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (327 kB)
P11 - Statistical Analysis of Survival Data (24 kB)
P14 - Individual Animal Pathology Data (1 mB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (616 kB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (54 kB)
P40 - Survival Curves (64 kB)

Individual Animal Data

Female Individual Animal Body Weight Data (358 kB)
Female Individual Animal Clinical Observations (154 kB)
Female Individual Animal Neoplastic Pathology Data (105 kB)
Female Individual Animal Non Neoplastic Pathology Data (634 kB)
Female Individual Animal Organ Weight Data (57 kB)
Female Individual Animal Survival Data (34 kB)
Male Individual Animal Body Weight Data (362 kB)
Male Individual Animal Clinical Observations (153 kB)
Male Individual Animal Neoplastic Pathology Data (93 kB)
Male Individual Animal Non Neoplastic Pathology Data (723 kB)
Male Individual Animal Organ Weight Data (57 kB)
Male Individual Animal Survival Data (34 kB)

Data

Evaluation of the Chronic Toxicity and Carcinogenicity (C20515) of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in B6C3F1 Mice via Whole Body Respiratory Exposure

Study Tables

E03 - Growth Curves (64 kB)
E04 - Mean Body Weights and Survival Table (24 kB)
E05 - Clinical Observations Summary (20 kB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (62 kB)
P04 - Neoplasms by Individual Animal (728 kB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (52 kB)
P08 - Statistical Analysis of Primary Tumors (204 kB)
P09 - Non-Neoplastic Lesions by Individual Animal (885 kB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (375 kB)
P14 - Individual Animal Pathology Data (1 mB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (647 kB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (64 kB)
P40 - Survival Curves (63 kB)

Individual Animal Data

Female Individual Animal Body Weight Data (372 kB)
Female Individual Animal Clinical Observations (62 kB)
Female Individual Animal Neoplastic Pathology Data (242 kB)
Female Individual Animal Non Neoplastic Pathology Data (647 kB)
Female Individual Animal Organ Weight Data (57 kB)
Female Individual Animal Survival Data (34 kB)
Male Individual Animal Body Weight Data (345 kB)
Male Individual Animal Clinical Observations (73 kB)
Male Individual Animal Neoplastic Pathology Data (132 kB)
Male Individual Animal Non Neoplastic Pathology Data (624 kB)
Male Individual Animal Organ Weight Data (57 kB)
Male Individual Animal Survival Data (34 kB)

Protocol

Genetic Toxicology Studies

Data

Genetic Toxicity Evaluation of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in Micronucleus Study F06575 in B6C3F1 Mice

Summary and Individual Animal Data

G04 - In Vivo Micronucleus Summary Data (77 KB)
Individual Animal In Vivo Micronucleus Data (10 KB)

Data

Genetic Toxicity Evaluation of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in Micronucleus Study F64536 in F344/NTac Rats

Summary and Individual Animal Data

G04 - In Vivo Micronucleus Summary Data (77 KB)
Individual Animal In Vivo Micronucleus Data (10 KB)

Data

Genetic Toxicity Evaluation of Metal Working Fluids: CIMSTAR 3800 in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A69652

Summary Data

G06 - Ames Summary Data (76 KB)

CIMSTAR 3800 (CIMSTAR3800)

Study Results

Chronic Bioassay Level of Evidence

Genetic Toxicology

Citation Information

Related Links

Publications

Study Data

Toxicity and Carcinogenicity Studies

3-Month Evaluation of the Toxicity (C20515) of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in F344/NTac Rats via Whole Body Respiratory Exposure

Study Tables

Individual Animal Data

3-Month Evaluation of the Toxicity (C20515) of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in B6C3F1 Mice via Whole Body Respiratory Exposure

Study Tables

Individual Animal Data

Evaluation of the Chronic Toxicity and Carcinogenicity (C20515) of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in Wistar Han Rats via Whole Body Respiratory Exposure

Study Tables

Individual Animal Data

Evaluation of the Chronic Toxicity and Carcinogenicity (C20515) of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in B6C3F1 Mice via Whole Body Respiratory Exposure

Study Tables

Individual Animal Data

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in Micronucleus Study F06575 in B6C3F1 Mice

Summary and Individual Animal Data

Genetic Toxicity Evaluation of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in Micronucleus Study F64536 in F344/NTac Rats

Summary and Individual Animal Data

Genetic Toxicity Evaluation of Metal Working Fluids: CIMSTAR 3800 in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A69652

Summary Data

NTP Data Collections