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p-Chloro-a,a,a-trifluorotoluene (98-56-6)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to p-Chloro-a,a,a-trifluorotoluene (98-56-6).
Micronucleus - Rats
View
  • Male: Equivocal
    Female: Negative
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to p-Chloro-a,a,a-trifluorotoluene (98-56-6).
Micronucleus - Mice
View
  • Male: Positive
    Female: Equivocal
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to p-Chloro-a,a,a-trifluorotoluene (98-56-6).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. p-Chloro-a,a,a-trifluorotoluene (98-56-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2020-08-09. https://manticore.niehs.nih.gov/cebssearch/test_article/98-56-6

Publications


TR-594 Toxicology and Carcinogenesis Studies of p-Chloro-α,α,α-trifluorotoluene (CAS No. 98-56-6) in Sprague Dawley Rats (Hsd: Sprague Dawley SD) and B6C3F1/N Mice (Inhalation Studies)
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C10472) of p-Chloro-a,a,a-trifluorotoluene (98-56-6) in Harlan Sprague-Dawley Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C10472) of p-Chloro-a,a,a-trifluorotoluene (98-56-6) in B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C10472B) of p-Chloro-a,a,a-trifluorotoluene (98-56-6 ) in Harlan Sprague-Dawley Rats Exposed via Whole Body Respiratory Exposure
Study Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C10472B) of p-Chloro-a,a,a-trifluorotoluene (98-56-6 ) in B6C3F1 Mice Exposed via Whole Body Respiratory Exposure
Study Tables
Individual Animal Data

Genetic Toxicology Studies


Genetic Toxicity Evaluation of p-Chloro-a,a,a-trifluorotoluene (98-56-6) in Micronucleus Study G10472 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of p-Chloro-a,a,a-trifluorotoluene (98-56-6) in Micronucleus Study G10472B in B6C3F1 Mice
Genetic Toxicity Evaluation of p-Chloro-a,a,a-trifluorotoluene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 176994
Summary Data
Genetic Toxicity Evaluation of p-Chloro-a,a,a-trifluorotoluene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10472C
Summary Data