COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

N-Methylolacrylamide (924-42-5)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to N-Methylolacrylamide (924-42-5).
Micronucleus - Mice
View
  • Male: Negative
View
  • Male: Negative
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to N-Methylolacrylamide (924-42-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to N-Methylolacrylamide (924-42-5).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. N-Methylolacrylamide (924-42-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-352 Toxicology and Carcinogenesis Studies of N-Methylolacrylamide (CASRN 924-42-5) in F344/N Rats and B6C3F1 Mice
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Witt KL, Hughes L, Burka LT, McFee A, Bishop JB. Mouse bone marrow micronucleus test results do not predict the germ cell mutagenicity of N-hydroxy-methylacrylamide in the mouse dominant lethal assay. Environ. Mol. Mutagen Vol. 41 (2003) 111-120

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C60333) of N-Methylolacrylamide (924-42-5) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C60333) of N-Methylolacrylamide (924-42-5) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of N-Methylolacrylamide (924-42-5) in Micronucleus Study 081496 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of N-Methylolacrylamide (924-42-5) in Micronucleus Study A49398 in C3H Mice
Genetic Toxicity Evaluation of N-Methylolacrylamide (924-42-5) in Micronucleus Study A92682 in B6C3F1 Mice
Genetic Toxicity Evaluation of N-Methylolacrylamide in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 155882
Summary Data

Other NTP Studies


ADME/TK Evaluation (S0817) of N-Methylolacrylamide (924-42-5) in F344/N Rats and B6C3F1 Mice Exposed via Dosed Water, Gavage, or Intraperitoneal Injection
Data Summary