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Polysorbate 80 (9005-65-6)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Equivocal Evidence, Male, Rats
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Polysorbate 80 (9005-65-6).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Polysorbate 80 (9005-65-6).
Bacterial Mutagenicity
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  • Negative

Citation Information


NTP. Polysorbate 80 (9005-65-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2019-07-22. https://manticore.niehs.nih.gov/cebssearch/test_article/9005-65-6

Publications


TR-415 Toxicology and Carcinogenesis Studies of Polysorbate 80 (CASRN 9005-65-6) in F344/N Rats and B6C3F1 Mice (Feed Studies)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Final Report on the Developmental Toxicity of Polyoxyethylene Sorbitan Monooleate in Sprague-Dawley Rats

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C60286) of Polysorbate 80 (Glycol) (9005-65-6) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C60286) of Polysorbate 80 (Glycol) (9005-65-6) in B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Polysorbate 80 (Glycol) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 405466

Other NTP Studies


Prenatal Developmental Toxicity Study (TER91009) of Polysorbate 80 (Glycol) (9005-65-6) in Sprague-Dawley Rats Exposed via Gavage