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Dibutyl phthalate (84-74-2)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus study conclusions related to Dibutyl phthalate (84-74-2).
Micronucleus - Mice
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  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Dibutyl phthalate (84-74-2).
Mammalian Cell Mutagenicity
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  • Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Dibutyl phthalate (84-74-2).
Bacterial Mutagenicity
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  • Negative

Citation Information


NTP. Dibutyl phthalate (84-74-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2019-08-22. https://manticore.niehs.nih.gov/cebssearch/test_article/84-74-2

Publications


TOX-30 Toxicity Studies of Dibutyl Phthalate (CASRN 84-74-2) Administered in Feed to F344/N Rats and B6C3F1Mice
Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. Mutagenicity testing of Di(2-ethylhexyl)phthalate and related chemicals in Salmonella Environ. Mutagen. Vol. 7 (1985) 213-232

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Sprague-Dawley Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Sprague-Dawley Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
2-Week Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Syrian Golden Hamsters Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Syrian Golden Hamsters Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Syrian Golden Hamsters Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Syrian Golden Hamsters Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Syrian Golden Hamsters Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Syrian Golden Hamsters Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Micronucleus Study A17278 in B6C3F1 Mice
Genetic Toxicity Evaluation of Peroxisome Project (Dibutyl Phthalate) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 077089

Other NTP Studies


Toxicokinetic Evaluation (S0545) of Di-n-Butyl Phthalate (84-74-2) in Sprague-Dawley Rats, Syrian Golden Hamsters, and B6C3F1 Mice Exposed via Dosed Feed, Intravenous Injection or Gavage
Toxicokinetic Evaluation (S0580) of Di-n-Butyl Phthalate (84-74-2) in Sprague-Dawley Rats, Syrian Golden Hamsters, and B6C3F1 Mice Exposed via Dosed Feed
Data