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Diethylphthalate (84-66-2)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Equivocal Evidence, Female, Mice
  • Equivocal Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Diethylphthalate (84-66-2).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Diethylphthalate (84-66-2).
Bacterial Mutagenicity
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  • Negative
View
  • Negative

Citation Information


NTP. Diethylphthalate (84-66-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2019-07-22. https://manticore.niehs.nih.gov/cebssearch/test_article/84-66-2

Publications


TR-429 Toxicology and Carcinogenesis Studies of Diethylphthalate (CASRN 84-66-2) in F344/N Rats and B6C3F1 Mice (Dermal Studies) with Dermal Initiation/Promotion Study of Diethylphthalate and Dimethylphthalate (CASRN 131-11-3) in Male Swiss (CD-1®) Mice
Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. Mutagenicity testing of Di(2-ethylhexyl)phthalate and related chemicals in Salmonella Environ. Mutagen. Vol. 7 (1985) 213-232
Developmental Toxicity Evaluation of Diethyl Phthalate Administered to CD Rats on Gestational Days 6 through 15

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C60048B) of Diethyl Phthalate (84-66-2) in F344/N Rats Exposed via Topical Application
Evaluation of the Chronic Toxicity and Carcinogenicity (C60048B) of Diethyl Phthalate (84-66-2) in B6C3F1 Mice Exposed via Topical Application

Other NTP Studies


Prenatal Developmental Toxicity Study (TER88065) of Diethyl Phthalate (84-66-2) in Sprague-Dawley Rats Exposed via Dosed Feed