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D & C yellow no 11 (8003-22-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7024906


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Some Evidence, Female, Rats
  • Some Evidence, Male, Rats

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to D & C yellow no 11 (8003-22-3).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to D & C yellow no 11 (8003-22-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to D & C yellow no 11 (8003-22-3).
Bacterial Mutagenicity
View
  • Weakly Positive
View
  • Equivocal

Citation Information


NTP. D & C yellow no 11 (8003-22-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-463 Toxicology and Carcinogenesis Studies of D&C Yellow No. 11 (CASRN 8003-22-3) in F344 Rats (Feed Studies)
TOX-08 Toxicity Studies of D&C Yellow No. 11 in F344/N Rats and B6C3F1Mice (Feed Studies) (CASRN 8003-22-3)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C61789) of D & C Yellow No. 11 (8003-22-3) in F344/N Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C61789) of D & C Yellow No. 11 (8003-22-3) in B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C61789B) of D & C Yellow No. 11 (8003-22-3) in F344/N Rats Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of D & C Yellow No. 11 (8003-22-3) in Micronucleus Study A51491 in B6C3F1 Mice
Genetic Toxicity Evaluation of D & C Yellow No. 11 in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 231115
Summary Data
Genetic Toxicity Evaluation of D & C Yellow No. 11 in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 686247
Summary Data

Other NTP Studies


ADME/TK Evaluation (S0085) of D&C Yellow No. 11 (8003-22-3) in F344 Rats Exposed via Dosed Feed or Intravenous Injection