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Dichloroacetic acid (79-43-6)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Dichloroacetic acid (79-43-6).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Positive
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Dichloroacetic acid (79-43-6).
Bacterial Mutagenicity
View
  • Positive
View
  • Positive

Citation Information


NTP. Dichloroacetic acid (79-43-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2020-09-18. https://manticore.niehs.nih.gov/cebssearch/test_article/79-43-6

Publications


GMM-11 Toxicology Studies of Dichloroacetic Acid (CASRN 79-43-6) in Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal and Drinking Water Studies) and Carcinogenicity Studies of Dichloroacetic Acid in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Drinking Water Studies)

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C96016) of Water Disinfection Byproducts (Dichloroacetic Acid) (79-43-6) in F344 Rats Exposed via Dosed Water. NTP Special Study
3-Month Evaluation of the Toxicity (C96016) of Water Disinfection Byproducts (Dichloroacetic Acid) (79-43-6) in B6C3F1 Mice Exposed via Dosed Water. NTP Special Study
2-Week Evaluation of the Toxicity (C97013D) of Water Disinfection Model (Dichloroacetic Acid) (79-43-6) in FVB/N Mice Exposed via Topical Application
2-Week Evaluation of the Toxicity (C97013D) of Water Disinfection Model (Dichloroacetic Acid) (79-43-6) in FVB/N Mice Exposed via Topical Application
26-39 Week Evaluation of the Toxicity (C97013I) of Water Disinfection Model (Dichloroacetic Acid) (79-43-6) in P53(C57BL/6) Mice Exposed via Dosed Water
26-Week Evaluation of the Toxicity (C97013C) of Water Disinfection Model (Dichloroacetic Acid) (79-43-6) in P53(C57BL/6) Mice Exposed via Dosed Water
26-39 Week Evaluation of the Toxicity (C97013D) of Water Disinfection Model (Dichloroacetic Acid) (79-43-6) in Tg.AC Mice Exposed via Topical Application
26-39 Week Evaluation of the Toxicity (C97013I) of Water Disinfection Model (Dichloroacetic Acid) (79-43-6) in Tg.AC Mice Exposed via Dosed Water
26-Week Evaluation of the Toxicity (C97013C) of Water Disinfection Model (Dichloroacetic Acid) (79-43-6) in Tg.AC Mice Exposed via Dosed Water
26-Week Evaluation of the Toxicity (C97013D) of Water Disinfection Model (Dichloroacetic Acid) (79-43-6) in Tg.AC Mice Exposed via Topical Application
3-Month Evaluation of the Toxicity (C96016) of Water Disinfection Byproducts (Dichloroacetic Acid) (79-43-6) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C96016) of Water Disinfection Byproducts (Dichloroacetic Acid) (79-43-6) in B6C3F1 Mice Exposed via Dosed Water

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dichloroacetic Acid) (79-43-6) in Micronucleus Study A15985 in Tg.AC (FVB/N) Mice
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dichloroacetic Acid) (79-43-6) in Micronucleus Study A67778 in B6C3F1 Mice
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dichloroacetic Acid) (79-43-6) in Micronucleus Study A72842 in Tg.AC (FVB/N) Mice
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dichloroacetic Acid) (79-43-6) in Micronucleus Study A91472 in P53 +/- (C57BL/6) Mice
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dichloroacetic Acid) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 024933
Summary Data
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dichloroacetic Acid) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A67820
Summary Data

Other NTP Studies


28-Day Immunotoxicity Evaluation (IMM98003) of Water Disinfection Byproducts (Dichloroacetic Acid) (79-43-6) in B6C3F1 Mice via Dosed Water
B6CF1 Mice Individual and Summary Data
Toxicokinetic Evaluation (C96016) of Dichloroacetic Acid (79-43-6) in F344/N Rats and B6C3F1 Mice Exposed via Gavage or Intravenous Injection and Dosed Water (with and without Challenge)