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Sodium nitrite (7632-00-0)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Equivocal Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus study conclusions related to Sodium nitrite (7632-00-0).
Micronucleus - Mice
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  • Male: Negative
    Female: Negative
View
  • Male: Negative
An overview of Genetic Toxicology Micronucleus study conclusions related to Sodium nitrite (7632-00-0).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Sodium nitrite (7632-00-0).
Bacterial Mutagenicity
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  • Positive

Citation Information


NTP. Sodium nitrite (7632-00-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2019-08-22. https://manticore.niehs.nih.gov/cebssearch/test_article/7632-00-0

Publications


TR-495 Toxicology and Carcinogenesis Studies of Sodium Nitrite (CASRN 7632-00-0) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in F344 Rats Exposed via Dosed Water. NTP Special Study
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in B6C3F1 Mice Exposed via Dosed Water. NTP Special Study
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in B6C3F1 Mice Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C88007B) of Sodium Nitrite (7632-00-0) in F344/N Rats Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C88007B) of Sodium Nitrite (7632-00-0) in B6C3F1 Mice Exposed via Dosed Water

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Sodium Nitrite (7632-00-0) in Micronucleus Study A10342 in F344 Rats
Genetic Toxicity Evaluation of Sodium Nitrite (7632-00-0) in Micronucleus Study A17282 in B6C3F1 Mice
Genetic Toxicity Evaluation of Sodium Nitrite (7632-00-0) in Micronucleus Study A52858 in B6C3F1 Mice
Genetic Toxicity Evaluation of Sodium Nitrite in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 359703

Other NTP Studies


Toxicokinetic Evaluation (S0548) of Sodium Nitrite (7632-00-0) in F344/N Rats and B6C3F1 Mice Exposed via Intravenous Injection