COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

Sodium nitrite (7632-00-0)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Equivocal Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to Sodium nitrite (7632-00-0).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Sodium nitrite (7632-00-0).
Micronucleus - Mice
View
  • Male: Negative
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Sodium nitrite (7632-00-0).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. Sodium nitrite (7632-00-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2020-09-18. https://manticore.niehs.nih.gov/cebssearch/test_article/7632-00-0

Related Links

Publications

TR-495 Toxicology and Carcinogenesis Studies of Sodium Nitrite (CASRN 7632-00-0) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141

Study Data

Protocol

Toxicity and Carcinogenicity Studies

3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in F344 Rats Exposed via Dosed Water. NTP Special Study
Pathology Tables
Individual Animal Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in B6C3F1 Mice Exposed via Dosed Water. NTP Special Study
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in F344/N Rats Exposed via Dosed Water
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in F344/N Rats Exposed via Dosed Water
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in B6C3F1 Mice Exposed via Dosed Water
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C88007B) of Sodium Nitrite (7632-00-0) in F344/N Rats Exposed via Dosed Water
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C88007B) of Sodium Nitrite (7632-00-0) in B6C3F1 Mice Exposed via Dosed Water
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Sodium Nitrite (7632-00-0) in Micronucleus Study A10342 in F344 Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Sodium Nitrite (7632-00-0) in Micronucleus Study A17282 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Sodium Nitrite (7632-00-0) in Micronucleus Study A52858 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Sodium Nitrite in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 359703
Summary Data

Other NTP Studies

Toxicokinetic Evaluation (S0548) of Sodium Nitrite (7632-00-0) in F344/N Rats and B6C3F1 Mice Exposed via Intravenous Injection
Data

NTP Data Collections