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1,1-Dichloroethane (75-34-3)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Negative, Male, Rats
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  • Equivocal, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Negative, Male, Mice
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  • Equivocal, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 1,1-Dichloroethane (75-34-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 1,1-Dichloroethane (75-34-3).
Bacterial Mutagenicity
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  • Negative

Citation Information


NTP. 1,1-Dichloroethane (75-34-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2019-07-22. https://manticore.niehs.nih.gov/cebssearch/test_article/75-34-3

Publications


TR-066 Bioassay of 1,1-Dichloroethane for Possible Carcinogenicity (CASRN 75-34-3)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of 1,1-Dichloroethane (75-34-3) in Male Osborne-Mendel Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,1-Dichloroethane (75-34-3) in Female Osborne-Mendel Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,1-Dichloroethane (75-34-3) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,1-Dichloroethane (75-34-3) in Female B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 1,1-Dichloroethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 777132