Trimethoprim (738-70-5)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3023712
Study Results
Genetic Toxicology
Mammalian Cell Cytogenetics | |
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CA | SCE |
Bacterial Mutagenicity |
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Publications
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Galloway, S., Bloom, A., Resnick, M., Margolin, B., Nakamura, F., Archer, P., and Zeiger, E. Development of a standard protocol for in vitro cytogenetic testing with CHO cells: Comparison of results for 22 compounds in two laboratories. Environ. Mutagen. Vol. 7 (1985) 1-52
Study Data
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Trimethoprim in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 615417
Summary Data
- G06 - Ames Summary Data (141 KB)
Other NTP Studies
Toxicokinetic Evaluation (S0609) of 3'-Azido-3'-deoxythymidine (30516-87-1) and 3'-Azido-3'-deoxythymidine + Trimethoprim and Sulfamethoxazole (AZTTMPSMX) in B6C3F1 Mice Exposed via Intravenous Injection or Gavage
Data - AZT + TMP/SMX (Mixture) Combination
- Data Summary (Multiple-Dose Gavage) (125 kB)
- Data Summary (Single-Dose Gavage followed by IV) (123 kB)
- Data Summary (Single-Dose Gavage) (127 kB)
Data - 3'-Azido-3'-deoxythymidine and AZT + TMP/SMX (Mixture) Combination
- Individual Animal Data (713 kB)
Data - 3'-Azido-3'-deoxythymidine (AZT)
- Data Summary (127 kB)