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Colchicine (64-86-8)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5024845


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Colchicine (64-86-8).
Rodent Cytogenetics
CA SCE
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    • Negative (Nonstandard Protocol)
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    • Negative
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    • Equivocal
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    • Negative
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    • Negative (Nonstandard Protocol)
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    • Positive
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    • Not a Valid Test
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    • Negative (Nonstandard Protocol)
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    • Positive
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    • Equivocal
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    • Positive
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    • Negative
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    • Equivocal
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    • Negative
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    • Negative (Nonstandard Protocol)
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    • Positive
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    • Negative
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    • Negative (Nonstandard Protocol)
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    • Positive
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    • Negative
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    • Negative (Nonstandard Protocol)
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    • Positive (Nonstandard Protocol)
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    • Negative
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    • Positive
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    • Negative (Nonstandard Protocol)
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    • Positive
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    • Positive (Nonstandard Protocol)
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    • Negative
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    • Positive
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    • Negative (Nonstandard Protocol)
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    • Negative
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    • Positive (Nonstandard Protocol)
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    • Positive (Nonstandard Protocol)
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    • Negative
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    • Negative
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    • Positive
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    • Positive (Nonstandard Protocol)
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    • Equivocal
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    • Negative (Nonstandard Protocol)
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    • Negative
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    • Negative (Nonstandard Protocol)
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    • Positive
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    • Negative
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    • Negative (Nonstandard Protocol)
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    • Positive (Nonstandard Protocol)
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    • Negative (Nonstandard Protocol)
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    • Not a Valid Test
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    • Positive
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    • Equivocal
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    • Negative
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    • Negative (Nonstandard Protocol)
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    • Not a Valid Test
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    • Positive
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    • Negative (Nonstandard Protocol)
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    • Equivocal
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    • Positive
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    • Negative (Nonstandard Protocol)
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    • Equivocal
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    • Negative (Nonstandard Protocol)
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    • Negative
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    • Negative (Nonstandard Protocol)
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    • Positive
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    • Positive (Nonstandard Protocol)
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    • Positive (Nonstandard Protocol)
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    • Negative (Nonstandard Protocol)
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    • Positive
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    • Negative
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    • Positive
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    • Negative
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    • Positive
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    • Positive (Nonstandard Protocol)
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    • Positive
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    • Positive (Nonstandard Protocol)
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    • Negative
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    • Positive (Nonstandard Protocol)
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    • Positive (Nonstandard Protocol)
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    • Negative (Nonstandard Protocol)
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An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Colchicine (64-86-8).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Colchicine (64-86-8).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Colchicine (64-86-8).
Bacterial Mutagenicity
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  • Negative

Citation Information


NTP. Colchicine (64-86-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TOX-45 Renal Toxicity Studies of Selected Halogenated Ethanes Administered by Gavage to F344/N Rats
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of Colchicine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 628962
Summary Data

Other NTP Studies


Screen for Developmental Toxicity in Zebrafish- Study 1
Results