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1,1,1,2-Tetrachloroethane (630-20-6)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to 1,1,1,2-Tetrachloroethane (630-20-6).
Rodent Cytogenetics
CA
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 1,1,1,2-Tetrachloroethane (630-20-6).
Micronucleus - Mice
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to 1,1,1,2-Tetrachloroethane (630-20-6).
Mammalian Cell Mutagenicity
View
  • Positive
View
  • Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 1,1,1,2-Tetrachloroethane (630-20-6).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to 1,1,1,2-Tetrachloroethane (630-20-6).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 1,1,1,2-Tetrachloroethane (630-20-6).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. 1,1,1,2-Tetrachloroethane (630-20-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2020-07-11. https://manticore.niehs.nih.gov/cebssearch/test_article/630-20-6

Publications


Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Myhr, B. and Caspary, W. Chemical mutagenesis at the TK locus in L5178Y mouse lymphoma cells. I. Results for 31 coded compounds in the National Toxicology Program. Environ. Molec. Mutagen. Vol. 18 (1991) 51-83
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of 1,1,1,2-Tetrachloroethane (630-20-6) in Micronucleus Study 299785 in B6C3F1 Mice
Genetic Toxicity Evaluation of 1,1,1,2-Tetrachloroethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 466226
Summary Data
Genetic Toxicity Evaluation of 1,1,1,2-Tetrachloroethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 806178
Summary Data