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Chlordane (57-74-9)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Negative, Male, Rats
View
  • Negative, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Positive, Male, Mice
View
  • Positive, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Chlordane (57-74-9).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Chlordane (57-74-9).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Chlordane (57-74-9). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-008 Bioassay of Chlordane for Possible Carcinogenicity (CASRN 57-74-9)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Chlordane (Analytical Grade) (57-74-9) in Male Osborne-Mendel Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Chlordane (Analytical Grade) (57-74-9) in Female Osborne-Mendel Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Chlordane (Analytical Grade) (57-74-9) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Chlordane (Analytical Grade) (57-74-9) in Female B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Chlordane (Analytical Grade) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 779361
Summary Data