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1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)-ethanone (54464-57-2)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus study conclusions related to 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)-ethanone (54464-57-2).
Micronucleus - Mice
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  • Male: Equivocal
    Female: Positive
An overview of Genetic Toxicology Micronucleus study conclusions related to 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)-ethanone (54464-57-2).
Micronucleus - Rats
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  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)-ethanone (54464-57-2).
Bacterial Mutagenicity
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  • Negative
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  • Negative

Citation Information


NTP. 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)-ethanone (54464-57-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2019-04-25. https://manticore.niehs.nih.gov/cebssearch/test_article/54464-57-2

Publications


TOX-92 NTP Technical Report on the Toxicity Studies of Octahydro-tetramethyl-naphthalenyl-ethanone (OTNE) Administered Dermally to F344/NTac Rats and B6C3F1/N Mice

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C20307) of Ethanone, 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-Tetramethyl-2-Naphthalenyl)- (Iso-E Super; OTNE) (54464-57-2) in F344/NTac Rats Exposed via Topical Application
3-Month Evaluation of the Toxicity (C20307) of Ethanone, 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-Tetramethyl-2-Naphthalenyl)- (Iso-E Super; OTNE) (54464-57-2) in B6C3F1 Mice Exposed via Topical Application

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Ethanone, 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-Tetramethyl-2-Naphthalenyl)- (Iso-E Super; OTNE) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A39068
Genetic Toxicity Evaluation of Ethanone, 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-Tetramethyl-2-Naphthalenyl)- (Iso-E Super; OTNE) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99091