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Trimethylphosphate (512-56-1)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Positive, Male, Rats
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  • Negative, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Negative, Male, Mice
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  • Positive, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Trimethylphosphate (512-56-1).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Trimethylphosphate (512-56-1).
Bacterial Mutagenicity
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  • Positive

Citation Information


NTP. Trimethylphosphate (512-56-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2019-09-22. https://manticore.niehs.nih.gov/cebssearch/test_article/512-56-1

Publications


TR-081 Bioassay of Trimethylphosphate for Possible Carcinogenicity (CASRN 512-56-1)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Trimethylphosphate (512-56-1) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Trimethylphosphate (512-56-1) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Trimethylphosphate (512-56-1) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Trimethylphosphate (512-56-1) in Female B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Trimethylphosphate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 623229