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WY-14643 (50892-23-4)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus study conclusions related to WY-14643 (50892-23-4).
Micronucleus - Rats
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Micronucleus study conclusions related to WY-14643 (50892-23-4).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative

Citation Information


NTP. WY-14643 (50892-23-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2018-12-19. https://manticore.niehs.nih.gov/cebssearch/test_article/50892-23-4

Publications


TOX-62 Toxicity Studies of WY-14,643 (CAS No. 50892-23-4) Administered in Feed to Male Sprague-Dawley Rats, B6C3F1 Mice, and Syrian Hamsters
TOX-96 NTP Report on the Toxicity Studies of Perfluorinated Compounds: Sulfonates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats
TOX-97 NTP Report on the Toxicity Studies of Perfluorinated Compounds: Carboxylates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats

Study Data


Toxicity and Carcinogenicity Studies


28-Day Evaluation of the Toxicity (C91069) of Wyeth 14,643 (WY) (50892-23-4) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C55550E) of Methapyrilene hydrochloride (135-23-9) in F344 Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Sprague-Dawley Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Sprague-Dawley Rats Exposed via Dosed Feed. NTP Special Study
2-Week Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
2-Week Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Syrian Golden Hamsters Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Syrian Golden Hamsters Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Syrian Golden Hamsters Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Syrian Golden Hamsters Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Syrian Golden Hamsters Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Syrian Golden Hamsters Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Peroxisome Project (WY-14643) (50892-23-4) in Micronucleus Study A06279 in Tg.AC (FVB/N) Mice
Genetic Toxicity Evaluation of Peroxisome Project (WY-14643) (50892-23-4) in Micronucleus Study A71798 in Tg.AC (FVB/N) Mice
Genetic Toxicity Evaluation of Peroxisome Project (WY-14643) (50892-23-4) in Micronucleus Study G91069 in Harlan Sprague-Dawley Rats

Other NTP Studies


Toxicokinetic Evaluation (S0583) of Wyeth-14643 (50892-23-4) in Sprague-Dawley Rats, Syrian Golden Hamsters and B6C3F1 Mice Exposed via Dosed Feed
Data
Toxicokinetic Evaluation (S0629) of Wyeth-14643 (50892-23-4) in Wistar Furth Rats, Sprague-Dawley Rats, Syrian Golden Hamsters and B6C3F1 Mice via Dosed Feed, Gavage or Intravenous Injection