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Vinpocetine (42971-09-5)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Vinpocetine (42971-09-5).
Micronucleus - Mice
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  • Female: Negative
An overview of Genetic Toxicology In Vivo Alkaline Comet Assay Mice study conclusions related to Vinpocetine (42971-09-5).
In Vivo Alkaline Comet Assay - Mice
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  • Female: Equivocal
An overview of Genetic Toxicology In Vitro Micronucleus study conclusions related to Vinpocetine (42971-09-5).
In Vitro Micronucleus
View
  • Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Vinpocetine (42971-09-5).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Vinpocetine (42971-09-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2020-07-11. https://manticore.niehs.nih.gov/cebssearch/test_article/42971-09-5

Publications


DART-03 Prenatal Developmental Toxicity Studies of Vinpocetine in Sprague Dawley (Hsd:Sprague Dawley SD) Rats and New Zealand White (Hra:NZW SPF) Rabbits (Gavage Studies)
Systemic Exposure of Vinpocetine in Pregnant Sprague Dawley Rats Following Repeated Oral Exposure: An Investigation of Fetal Transfer Suramya Waidyanatha, Heather Toy, Natalie South, Seth Gibbs, Esra Mutlu, Brian Burback, Barry S.McIntyre, and Natasha Catlin.
Toxicology and Applied Pharmacology (2018) DOI: https://doi.org/10.1016/j.taap.2017.11.011 PMID: 29155086

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of Vinpocetine (42971-09-5) in DNA Damage Study G12103D in B6C3F1 Mice
Genetic Toxicity Evaluation of Vinpocetine (42971-09-5) in Micronucleus Study G12103C in B6C3F1 Mice
Genetic Toxicity Evaluation of Vinpocetine (42971-09-5) in Micronucleus Study G12103E in Human TK6 Cells
Genetic Toxicity Evaluation of Vinpocetine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G12103
Summary Data

Other NTP Studies


Prenatal Developmental Toxicity Dose Range Finding Study (R12103) of Vinpocetine (42971-09-5) in Harlan Sprague-Dawley Rats Exposed via Gavage
Prenatal Developmental Toxicity Dose Range Finding Study (R12103D) of Vinpocetine (42971-09-5) in New Zealand White Rabbits Exposed via Gavage
Prenatal Developmental Toxicity Study (R12103B) of Vinpocetine (42971-09-5) in Harlan Sprague-Dawley Rats Exposed via Gavage