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Pentabromodiphenyl oxide (32534-81-9)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus study conclusions related to Pentabromodiphenyl oxide (32534-81-9).
Micronucleus - Mice
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  • Male: Negative
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  • Male: Negative
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  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Pentabromodiphenyl oxide (32534-81-9).
Bacterial Mutagenicity
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  • Negative
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  • Negative
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  • Negative

Citation Information


NTP. Pentabromodiphenyl oxide (32534-81-9). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2019-09-22. https://manticore.niehs.nih.gov/cebssearch/test_article/32534-81-9

Publications


TR-589 Toxicology Studies of a Pentabromodiphenyl Ether Mixture [DE-71 (Technical Grade)] (CASRN 32534-81-9) in F344/N Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of a Pentabromodiphenyl Ether Mixture [DE-71 (Technical Grade)] in Wistar Han [Crl:WI(Han)] Rats and B6C3F1/N Mice (Gavage Studies)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
Witt KL, Livanos E, Kissling GE, Torous DK, Caspary W, Tice RR, Recio L. Comparison of flow cytometry- and microscopy-based methods for measuring micronucleated reticulocyte frequencies in rodents treated with nongenotoxic and genotoxic chemicals. Mutat Res. 2008 Jan 8;649(1-2):101-13. Epub 2007 Aug 11.

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C20209) of Pentabromodiphenyl Oxide (Technical) (DE 71) (32534-81-9) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20209) of Pentabromodiphenyl Oxide (Technical) (DE 71) (32534-81-9) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20209) of Pentabromodiphenyl Oxide (Technical) (DE 71) (32534-81-9) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20209) of Pentabromodiphenyl Oxide (Technical) (DE 71) (32534-81-9) in Wistar Han Rats Exposed via Gavage
Study Tables
Interim of Chronic Study at 3-Months
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C20209) of Pentabromodiphenyl Oxide (Technical) (DE 71) (32534-81-9) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Pentabromodiphenyl Oxide (Technical) (DE 71) (32534-81-9) in Micronucleus Study A27878 in B6C3F1 Mice
Genetic Toxicity Evaluation of Pentabromodiphenyl Oxide (Technical) (DE 71) (32534-81-9) in Micronucleus Study A34110 in B6C3F1 Mice
Genetic Toxicity Evaluation of Pentabromodiphenyl Oxide (Technical) (DE 71) (32534-81-9) in Micronucleus Study F34110 in B6C3F1 Mice
Genetic Toxicity Evaluation of Pentabromodiphenyl Oxide (Technical) (DE 71) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 873255
Genetic Toxicity Evaluation of Pentabromodiphenyl Oxide (Technical) (DE 71) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A82572
Genetic Toxicity Evaluation of Pentabromodiphenyl Oxide (Technical) (DE 71) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A83261