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3,3',4,4'-Tetrachloroazoxybenzene (21232-47-3)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus study conclusions related to 3,3',4,4'-Tetrachloroazoxybenzene (21232-47-3).
Micronucleus - Mice
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  • Male: Negative
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  • Male: Positive
    Female: Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 3,3',4,4'-Tetrachloroazoxybenzene (21232-47-3).
Bacterial Mutagenicity
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  • Negative

Citation Information


NTP. 3,3',4,4'-Tetrachloroazoxybenzene (21232-47-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2019-06-17. https://manticore.niehs.nih.gov/cebssearch/test_article/21232-47-3

Publications


TOX-66 Toxicity Studies of 3,3',4,4'-Tetrachloroazoxybenzene Administered by Gavage to F344/N Rats and B6C3F1Mice (CASRN 21232-47-3)
Witt, K.L., Zeiger, E., Tice, R.R., and van Birgelen, A.P.J.M. The genetic toxicity of 3,3',4,4'-tetrachloroazobenzene and 3,3',4,4'-tetrachloroazoxybenzene: discordance between acute mouse bone marrow and subchronic mouse peripheral blood micronucleus test results. Mutation Res. Vol. 472 (2000) 147-154

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C88149) of 3,3',4,4'-Tetrachloroazoxybenzene (21232-47-3) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C88149) of 3,3',4,4'-Tetrachloroazoxybenzene (21232-47-3) in F344 Rats Exposed via Gavage. NTP Special Study
2-Week Evaluation of the Toxicity (C88149) of 3,3',4,4'-Tetrachloroazoxybenzene (21232-47-3) in B6C3F1 Mice Exposed via Gavage
3-Month Evaluation of the Toxicity (C88149) of 3,3',4,4'-Tetrachloroazoxybenzene (21232-47-3) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C88149) of 3,3',4,4'-Tetrachloroazoxybenzene (21232-47-3) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C88149) of 3,3',4,4'-Tetrachloroazoxybenzene (21232-47-3) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 3,3',4,4'-Tetrachloroazoxybenzene (21232-47-3) in Micronucleus Study A27535 in B6C3F1 Mice
Genetic Toxicity Evaluation of 3,3',4,4'-Tetrachloroazoxybenzene (21232-47-3) in Micronucleus Study A78292 in B6C3F1 Mice
Genetic Toxicity Evaluation of 3,3',4,4'-Tetrachloroazoxybenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A88322