Trimethylsilyldiazomethane (18107-18-1)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID8074653
Publications
TOX-101
NTP Technical Report on the Toxicity Studies of Trimethylsilyldiazomethane (CASRN 18107-18-1) Administered by Nose-only Inhalation to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6C3F1/N Mice
Study Data
Toxicity and Carcinogenicity Studies
One-Day and Five-Day Evaluation of the Toxicity (C11049-01) of Trimethylsilyldiazomethane (18107-18-1) in Harlan Sprague Dawley Rats Exposed via Nose-Only Respiratory Exposure
Study Tables
- Growth Curves (146 kB)
- I01 - Animal Removal Summary (57 kB)
- I02 - Animal Removals (503 kB)
- I04 – Mean Body Weight Summary (204 kB)
- I04G – Mean Body Weight Gain (108 kB)
- I05 - Clinical Observations Summary (88 kB)
- PA02 - Neoplastic Lesion Summary with Percent Incidence (436 kB)
- PA03 - Non-Neoplastic Lesion Summary with Percent Incidence 6- (424 kB)
- PA05 - Incidence Rates of Neoplastic Lesions with Systemic Lesions Abridged (437 kB)
- PA08 - Statistical Analysis of Neoplastic Lesions (358 kB)
- PA10 - Statistical Analysis of Non-Neoplastic Lesions (439 kB)
- PA14 - Individual Animal Pathology Data (2 mB)
- PA18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grade (424 kB)
Individual Animal Data
One-Day and Five-Day Evaluation (C11049-02) of the Toxicity of Trimethylsilyldiazomethane (18107-18-1) in B6C3F1/N Mice via Nose-Only Respiratory Exposure
Study Tables
- Growth Curves (139 kB)
- I01 - Animal Removal Summary (69 kB)
- I02 - Animal Removals (503 kB)
- I04 – Mean Body Weight Summary (202 kB)
- I04G – Mean Body Weight Gain (108 kB)
- I05 - Clinical Observations Summary (108 kB)
- PA02 - Neoplastic Lesion Summary with Percent Incidence (437 kB)
- PA03 - Non-Neoplastic Lesion Summary with Percent Incidence (418 kB)
- PA05 - Incidence Rates of Neoplastic Lesions with Systemic Lesions Abridged (438 kB)
- PA08 - Statistical Analysis of Neoplastic Lesions (356 kB)
- PA10 - Statistical Analysis of Non-Neoplastic Lesions (431 kB)
- PA14 - Individual Animal Pathology Data (2 mB)
- PA18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grad (419 kB)
Individual Animal Data
- Individual_Animal_Body_Weight_Data.xlsx (33 kB)
- Individual_Animal_Clinical_Observations_Data.xlsx (80 kB)
- Individual_Animal_Gross_Pathology_Data.xlsx (267 kB)
- Individual_Animal_Histopathology_Data.xlsx (65 kB)
- Individual_Animal_Organ_Weight_Data.xlsx (16 kB)
- Individual_Animal_Removal_Reasons_Data.xlsx (8 kB)