Zearalenone (17924-92-4)

Study Results

Chronic Bioassay Level of Evidence

  • Negative, Male, Rats
  • Negative, Female, Rats
  • Positive, Male, Mice
  • Positive, Female, Mice

Genetic Toxicology

Mammalian Cell Mutagenicity
  • Negative
Mammalian Cell Cytogenetics
    • Positive
    • Positive
Drosophila Germ Cell Mutagenicity
    • Negative
Bacterial Mutagenicity
  • Negative

Citation Information

NTP. Zearalenone (17924-92-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2018-03-23. https://manticore.niehs.nih.gov/cebssearch/test_article/17924-92-4



Carcinogenesis Bioassay of Zearalenone (CASRN 17924-92-4) in F344/N Rats and B6C3F1 Mice (Feed Study)

Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119

McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154

Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227

Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data

Toxicity and Carcinogenicity