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Ziram (137-30-4)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Positive, Male, Rats
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  • Negative, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Negative, Male, Mice
View
  • Equivocal, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Ziram (137-30-4).
Rodent Cytogenetics
CA SCE
  • View
    • Negative (Nonstandard Protocol)
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Ziram (137-30-4).
Mammalian Cell Mutagenicity
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  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Ziram (137-30-4).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Ziram (137-30-4).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Ziram (137-30-4).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. Ziram (137-30-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2018-12-19. https://manticore.niehs.nih.gov/cebssearch/test_article/137-30-4

Publications


TR-238 Carcinogenesis Bioassay of Ziram (CASRN 137-30-4) in F344/N Rats and B6C3F1 Mice (Feed Study)
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III: Results with 27 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 133-193

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Ziram (137-30-4) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Ziram (137-30-4) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Ziram (137-30-4) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Ziram (137-30-4) in Female B6C3F1 Mice Exposed via Dosed Feed