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Pyrene (129-00-0)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Pyrene (129-00-0).
Rodent Cytogenetics
CA
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Pyrene (129-00-0).
Mammalian Cell Mutagenicity
View
  • Positive
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Pyrene (129-00-0).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Pyrene (129-00-0).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. Pyrene (129-00-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


Tice, R.R., Luke, C.A., Miller, V.M., Ormiston, B.G., Wilton, A.C., and Shelby, M.D. Comparative analysis of the induction of sister-chromatid exchanges in bone marrow cells of B6C3F1 mice. In Evaluation of Short-Term Tests for Carcinogens: Report of the IPCS Collaborative Study on In Vivo Assays, Cambridge Univ. Press, Cambridge, UK 1,254-1,259
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
Myhr, B.C., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for sixty-three coded chemicals tested at Litton Bionetics, Inc. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 103-194
Mitchell, A.D., Rudd, C.J., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for 63 coded chemicals tested at SRI International. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 37-102
Luke, C.A., Tice, R.R., Miller, V.M., Ormiston, B.G., Wilton, A.C., and Shelby, M.D. Comparative analysis of the induction of chromosome aberrations in the bone marrow cells of B6C3F1 mice. In Evaluation of Short-term Tests for Carcinogens: Report of the IPCS Collaborative Study on In Vivo Assays, Cambridge Univ. Press, Cambridge, UK Vol. (1988) 1,123-1,131

Study Data


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