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Isobutene (115-11-7)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • No Evidence, Female, Rats
  • Some Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus study conclusions related to Isobutene (115-11-7).
Micronucleus - Mice
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  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Isobutene (115-11-7).
Bacterial Mutagenicity
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  • Negative

Citation Information


NTP. Isobutene (115-11-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2018-09-19. https://manticore.niehs.nih.gov/cebssearch/test_article/115-11-7

Publications


TR-487 Toxicology and Carcinogenesis Studies of Isobutene (CASRN 115-11-7) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C88070) of Isobutene (115-11-7) in F344 Rats via Whole Body Respiratory Exposure. NTP Special Study
3-Month Evaluation of the Toxicity (C88070) of Isobutene (115-11-7) in B6C3F1 Mice via Whole Body Respiratory Exposure. NTP Special Study
3-Month Evaluation of the Toxicity (C88070) of Isobutene (115-11-7) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C88070) of Isobutene (115-11-7) in B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C88070) of Isobutene (115-11-7) in F344/N Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C88070) of Isobutene (115-11-7) in B6C3F1 Mice via Whole Body Respiratory Exposure