U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

4-Vinylcyclohexene (100-40-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3021437


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Inadequate Study, Male, Rats
View
  • Inadequate Study, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Inadequate Study, Male, Mice
View
  • Clear Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to 4-Vinylcyclohexene (100-40-3).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 4-Vinylcyclohexene (100-40-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 4-Vinylcyclohexene (100-40-3).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. 4-Vinylcyclohexene (100-40-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-303 Toxicology and Carcinogenesis Studies of 4-Vinylcyclohexene (CASRN 100-40-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of 4-Vinylcyclohexene (100-40-3) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 4-Vinylcyclohexene (100-40-3) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 4-Vinylcyclohexene (100-40-3) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 4-Vinylcyclohexene (100-40-3) in Female B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 4-Vinylcyclohexene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 609542
Summary Data
Genetic Toxicity Evaluation of 4-Vinylcyclohexene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 777152
Summary Data

Other NTP Studies


ADME/TK Evaluation (S0084) of 4-Vinylcyclohexene (100-40-3) in F344 Rats and B6C3F1 Mice Exposed via Gavage and Dermal Administration