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TR-495: Sodium nitrite (7632-00-0)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Equivocal Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus study conclusions related to TR-495: Sodium nitrite (7632-00-0).
Micronucleus - Mice
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  • Male: Negative
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Micronucleus study conclusions related to TR-495: Sodium nitrite (7632-00-0).
Micronucleus - Rats
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  • Male: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-495: Sodium nitrite (7632-00-0).
Bacterial Mutagenicity
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  • Positive

Citation Information


NTP. TR-495: Sodium nitrite (7632-00-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2020-01-27. https://manticore.niehs.nih.gov/cebssearch/publication/TR-495

Publications


TR-495 Toxicology and Carcinogenesis Studies of Sodium Nitrite (CASRN 7632-00-0) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in B6C3F1 Mice Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C88007B) of Sodium Nitrite (7632-00-0) in F344/N Rats Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C88007B) of Sodium Nitrite (7632-00-0) in B6C3F1 Mice Exposed via Dosed Water

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Sodium Nitrite (7632-00-0) in Micronucleus Study A10342 in F344 Rats
Genetic Toxicity Evaluation of Sodium Nitrite (7632-00-0) in Micronucleus Study A17282 in B6C3F1 Mice
Genetic Toxicity Evaluation of Sodium Nitrite (7632-00-0) in Micronucleus Study A52858 in B6C3F1 Mice
Genetic Toxicity Evaluation of Sodium Nitrite in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 359703