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TR-420: Triamterene (396-01-0)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Equivocal Evidence, Male, Rats
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Some Evidence, Female, Mice
  • Some Evidence, Male, Mice
View
  • Some Evidence, Female, Mice
  • Some Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-420: Triamterene (396-01-0).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-420: Triamterene (396-01-0).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. TR-420: Triamterene (396-01-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2020-08-09. https://manticore.niehs.nih.gov/cebssearch/publication/TR-420

Publications


TR-420 Toxicology and Carcinogenesis Studies of Triamterene (CASRN 396-01-0) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C56042B) of Triamterene (396-01-0) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C56042B) of Triamterene (396-01-0) in B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C56042B) of Triamterene (396-01-0) in B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Triamterene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 190695
Summary Data
Genetic Toxicity Evaluation of Triamterene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 303754
Summary Data