U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

TR-263: 1,2-Dichloropropane (78-87-5)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Male, Rats
View
  • Equivocal Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Some Evidence, Male, Mice
View
  • Some Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-263: 1,2-Dichloropropane (78-87-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-263: 1,2-Dichloropropane (78-87-5).
Bacterial Mutagenicity
View
  • Weakly Positive
View
  • Weakly Positive

Citation Information


NTP. TR-263: 1,2-Dichloropropane (78-87-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-263 Toxicology and Carcinogenesis Studies of 1,2-Dichloropropane (Propylene Dichloride) (CASRN 78-87-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Dichloropropane (Propylene Dichloride) (78-87-5) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Dichloropropane (Propylene Dichloride) (78-87-5) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Dichloropropane (Propylene Dichloride) (78-87-5) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Dichloropropane (Propylene Dichloride) (78-87-5) in Female B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 1,2-Dichloropropane (Propylene Dichloride) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 566847
Summary Data
Genetic Toxicity Evaluation of 1,2-Dichloropropane (Propylene Dichloride) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 627177
Summary Data