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TOX-97: Perfluorohexanoic acid (307-24-4), Perfluorooctanoic acid (335-67-1), Perfluorononanoic acid (375-95-1), Perfluorodecanoic acid (335-76-2), WY-14643 (50892-23-4)

DOI: http://doi.org/10.22427/NTP-OTHER-2

Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to TOX-97: Perfluorohexanoic acid (307-24-4), Perfluorooctanoic acid (335-67-1), Perfluorononanoic acid (375-95-1), Perfluorodecanoic acid (335-76-2), WY-14643 (50892-23-4).
Micronucleus - Rats
View
  • Male: Equivocal
    Female: Negative
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative
View
  • Male: Positive
    Female: Negative

Citation Information


NTP. TOX-97: Perfluorohexanoic acid (307-24-4), Perfluorooctanoic acid (335-67-1), Perfluorononanoic acid (375-95-1), Perfluorodecanoic acid (335-76-2), WY-14643 (50892-23-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2020-10-24. https://manticore.niehs.nih.gov/cebssearch/publication/TOX-97

Publications


TOX-97 NTP Report on the Toxicity Studies of Perfluorinated Compounds: Carboxylates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats

Study Data


Toxicity and Carcinogenicity Studies


28-Day Evaluation of the Toxicity (C04049) of Perfluorononanoic Acid (PFNA) (375-95-1) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
28-Day Evaluation of the Toxicity (C20613) of Perfluorohexanoic acid (PFHXA) (307-24-4) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
28-Day Evaluation of the Toxicity (C20615) of Perfluorodecanoic Acid (PFDA) (335-76-2) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
28-Day Evaluation of the Toxicity (C91069) of Wyeth 14,643 (WY) (50892-23-4) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
28-Day Evaluation of the Toxicity (C91070B) of Perfluorooctanoic Acid (PFOA) (335-67-1) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Perfluorodecanoic Acid (335-76-2) in Micronucleus Study G92006 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Perfluorohexanoic Acid (PFHXA) (307-24-4) in Micronucleus Study G04048 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Perfluorononanoic Acid (375-95-1) in Micronucleus Study G04049 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Perfluorooctanoic Acid (335-67-1) in Micronucleus Study G91070 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Peroxisome Project (WY-14643) (50892-23-4) in Micronucleus Study G91069 in Harlan Sprague-Dawley Rats