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TOX-96: 1-Perfluorobutanesulfonic acid (375-73-5), Potassium perfluorohexanesulfonate (3871-99-6), Perfluorooctane sulfonate (1763-23-1), WY-14643 (50892-23-4)

DOI: http://doi.org/10.22427/NTP-OTHER-1

Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus study conclusions related to TOX-96: 1-Perfluorobutanesulfonic acid (375-73-5), Potassium perfluorohexanesulfonate (3871-99-6), Perfluorooctane sulfonate (1763-23-1), WY-14643 (50892-23-4).
Micronucleus - Rats
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  • Male: Negative
    Female: Positive
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  • Male: Negative
    Female: Negative
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  • Male: Negative
    Female: Negative
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  • Male: Negative
    Female: Negative

Citation Information


NTP. TOX-96: 1-Perfluorobutanesulfonic acid (375-73-5), Potassium perfluorohexanesulfonate (3871-99-6), Perfluorooctane sulfonate (1763-23-1), WY-14643 (50892-23-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2019-12-14. https://manticore.niehs.nih.gov/cebssearch/publication/TOX-96

Publications


TOX-96 NTP Report on the Toxicity Studies of Perfluorinated Compounds: Sulfonates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats

Study Data


Toxicity and Carcinogenicity Studies


28-Day Evaluation of the Toxicity (C06100) of Perfluorohexane sulfonate potassium salt (PFHSKslt) (3871-99-6) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
28-Day Evaluation of the Toxicity (C07040) of Perfluorobutane sulfonate (PFBS) (375-73-5) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
28-Day Evaluation of the Toxicity (C20617) of Perfluorooctane Sulfonate (PFOS) (1763-23-1) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
28-Day Evaluation of the Toxicity (C91069) of Wyeth 14,643 (WY) (50892-23-4) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Perfluorobutane Sulfonate (PFBS) (375-73-5) in Micronucleus Study G04006 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Perfluorohexane Sulfonate Potassium Salt (PFHSKslt) (3871-99-6) in Micronucleus Study G06100 in Harlan Sprague-Dawley Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Perfluorooctane Sulfonate (1763-23-1) in Micronucleus Study G04004 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Peroxisome Project (WY-14643) (50892-23-4) in Micronucleus Study G91069 in Harlan Sprague-Dawley Rats