COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

TOX-96: 1-Perfluorobutanesulfonic acid (375-73-5), Potassium perfluorohexanesulfonate (3871-99-6), Perfluorooctane sulfonate (1763-23-1), WY-14643 (50892-23-4)

DOI: http://doi.org/10.22427/NTP-OTHER-1

Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to TOX-96: 1-Perfluorobutanesulfonic acid (375-73-5), Potassium perfluorohexanesulfonate (3871-99-6), Perfluorooctane sulfonate (1763-23-1), WY-14643 (50892-23-4).
Micronucleus - Rats
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Positive

Citation Information


NTP. TOX-96: 1-Perfluorobutanesulfonic acid (375-73-5), Potassium perfluorohexanesulfonate (3871-99-6), Perfluorooctane sulfonate (1763-23-1), WY-14643 (50892-23-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed 2020-09-18. https://manticore.niehs.nih.gov/cebssearch/publication/TOX-96

Publications


TOX-96 NTP Report on the Toxicity Studies of Perfluorinated Compounds: Sulfonates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats

Study Data


Toxicity and Carcinogenicity Studies


28-Day Evaluation of the Toxicity (C06100) of Perfluorohexane sulfonate potassium salt (PFHSKslt) (3871-99-6) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
28-Day Evaluation of the Toxicity (C07040) of Perfluorobutane sulfonate (PFBS) (375-73-5) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
28-Day Evaluation of the Toxicity (C20617) of Perfluorooctane Sulfonate (PFOS) (1763-23-1) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
28-Day Evaluation of the Toxicity (C91069) of Wyeth 14,643 (WY) (50892-23-4) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Perfluorobutane Sulfonate (PFBS) (375-73-5) in Micronucleus Study G04006 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Perfluorohexane Sulfonate Potassium Salt (PFHSKslt) (3871-99-6) in Micronucleus Study G06100 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Perfluorooctane Sulfonate (1763-23-1) in Micronucleus Study G04004 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Peroxisome Project (WY-14643) (50892-23-4) in Micronucleus Study G91069 in Harlan Sprague-Dawley Rats